| TRPM2 contributes to inflammatory and neuropathic pain through the aggravation of pronociceptive inflammatory responses in mice K Haraguchi, A Kawamoto, K Isami, S Maeda, A Kusano, K Asakura, ... Journal of Neuroscience 32 (11), 3931-3941, 2012 | 225 | 2012 |
| Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice M Zhao, K Isami, S Nakamura, H Shirakawa, T Nakagawa, S Kaneko Molecular pain 8, 1744-8069-8-55, 2012 | 217 | 2012 |
| TRPM2 channel aggravates CNS inflammation and cognitive impairment via activation of microglia in chronic cerebral hypoperfusion J Miyanohara, M Kakae, K Nagayasu, T Nakagawa, Y Mori, K Arai, ... Journal of Neuroscience 38 (14), 3520-3533, 2018 | 128 | 2018 |
| Endogenous D-serine is involved in induction of neuronal death by N-methyl-D-aspartate and simulated ischemia in rat cerebrocortical slices H Katsuki, M Nonaka, H Shirakawa, T Kume, A Akaike Journal of Pharmacology and Experimental Therapeutics 311 (2), 836-844, 2004 | 128 | 2004 |
| Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS T Miyake, S Nakamura, M Zhao, K So, K Inoue, T Numata, N Takahashi, ... Nature communications 7 (1), 12840, 2016 | 120 | 2016 |
| Activation of mitochondrial transient receptor potential vanilloid 1 channel contributes to microglial migration T Miyake, H Shirakawa, T Nakagawa, S Kaneko Glia 63 (10), 1870-1882, 2015 | 118 | 2015 |
| Gene transfer of GLT-1, a glial glutamate transporter, into the spinal cord by recombinant adenovirus attenuates inflammatory and neuropathic pain in rats S Maeda, A Kawamoto, Y Yatani, H Shirakawa, T Nakagawa, S Kaneko Molecular pain 4, 1744-8069-4-65, 2008 | 109 | 2008 |
| Transient receptor potential canonical 3 (TRPC3) mediates thrombin-induced astrocyte activation and upregulates its own expression in cortical astrocytes H Shirakawa, S Sakimoto, K Nakao, A Sugishita, M Konno, S Iida, ... Journal of Neuroscience 30 (39), 13116-13129, 2010 | 102 | 2010 |
| Manipulation of dorsal raphe serotonergic neurons modulates active coping to inescapable stress and anxiety-related behaviors in mice and rats N Nishitani, K Nagayasu, N Asaoka, M Yamashiro, C Andoh, Y Nagai, ... Neuropsychopharmacology 44 (4), 721-732, 2019 | 97 | 2019 |
| Raphe AMPA receptors and nicotinic acetylcholine receptors mediate ketamine-induced serotonin release in the rat prefrontal cortex N Nishitani, K Nagayasu, N Asaoka, M Yamashiro, H Shirakawa, ... International Journal of Neuropsychopharmacology 17 (8), 1321-1326, 2014 | 94 | 2014 |
| TRPV1 stimulation triggers apoptotic cell death of rat cortical neurons H Shirakawa, T Yamaoka, K Sanpei, H Sasaoka, T Nakagawa, S Kaneko Biochemical and biophysical research communications 377 (4), 1211-1215, 2008 | 93 | 2008 |
| Stimulation of transient receptor potential vanilloid 4 channel suppresses abnormal activation of microglia induced by lipopolysaccharide M Konno, H Shirakawa, S Iida, S Sakimoto, I Matsutani, T Miyake, ... Glia 60 (5), 761-770, 2012 | 92 | 2012 |
| TRPM2 contributes to LPS/IFNγ-induced production of nitric oxide via the p38/JNK pathway in microglia T Miyake, H Shirakawa, A Kusano, S Sakimoto, M Konno, T Nakagawa, ... Biochemical and biophysical research communications 444 (2), 212-217, 2014 | 81 | 2014 |
| TRP Channels in the Brain S Sawamura, H Shirakawa, T Nakagawa, Y Mori, S Kaneko Neurobiology of TRP channels, 2017 | 79 | 2017 |
| Prevention of antipsychotic-induced hyperglycaemia by vitamin D: a data mining prediction followed by experimental exploration of the molecular mechanism T Nagashima, H Shirakawa, T Nakagawa, S Kaneko Scientific reports 6 (1), 26375, 2016 | 77 | 2016 |
| Transient receptor potential canonical 3 inhibitor Pyr3 improves outcomes and attenuates astrogliosis after intracerebral hemorrhage in mice M Munakata, H Shirakawa, K Nagayasu, J Miyanohara, T Miyake, ... Stroke 44 (7), 1981-1987, 2013 | 77 | 2013 |
| Prediction of pharmacological activities from chemical structures with graph convolutional neural networks M Sakai, K Nagayasu, N Shibui, C Andoh, K Takayama, H Shirakawa, ... Scientific reports 11 (1), 525, 2021 | 76 | 2021 |
| Isolation of a diterpenoid substance with potent neuroprotective activity from fetal calf serum T Kume, N Asai, H Nishikawa, N Mano, T Terauchi, R Taguchi, ... Proceedings of the National Academy of Sciences 99 (5), 3288-3293, 2002 | 66 | 2002 |
| Involvement of TRPM2 in peripheral nerve injury-induced infiltration of peripheral immune cells into the spinal cord in mouse neuropathic pain model K Isami, K Haraguchi, K So, K Asakura, H Shirakawa, Y Mori, T Nakagawa, ... PloS one 8 (7), e66410, 2013 | 63 | 2013 |
| Hypoxia-induced sensitisation of TRPA1 in painful dysesthesia evoked by transient hindlimb ischemia/reperfusion in mice K So, Y Tei, M Zhao, T Miyake, H Hiyama, H Shirakawa, S Imai, Y Mori, ... Scientific reports 6 (1), 23261, 2016 | 61 | 2016 |
