| Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death JM Hildebrand, MC Tanzer, IS Lucet, SN Young, SK Spall, P Sharma, ... Proceedings of the National Academy of Sciences 111 (42), 15072-15077, 2014 | 568 | 2014 |
| DSB proteins and bacterial pathogenicity B Heras, SR Shouldice, M Totsika, MJ Scanlon, MA Schembri, JL Martin Nature Reviews Microbiology 7 (3), 215-225, 2009 | 340 | 2009 |
| Isolation, Solution Structure, and Insecticidal Activity of Kalata B2, a Circular Protein with a Twist: Do Möbius Strips Exist in Nature?, CV Jennings, KJ Rosengren, NL Daly, M Plan, J Stevens, MJ Scanlon, ... Biochemistry 44 (3), 851-860, 2005 | 284 | 2005 |
| Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor. NL Daly, MJ Scanlon, JT Djordjevic, PA Kroon, R Smith Proceedings of the National Academy of Sciences 92 (14), 6334-6338, 1995 | 224 | 1995 |
| Conformational selection of inhibitors and substrates by proteolytic enzymes: implications for drug design and polypeptide processing DP Fairlie, JDA Tyndall, RC Reid, AK Wong, G Abbenante, MJ Scanlon, ... Journal of Medicinal Chemistry 43 (7), 1271-1281, 2000 | 216 | 2000 |
| Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief DD Jensen, TM Lieu, ML Halls, NA Veldhuis, WL Imlach, QN Mai, ... Science Translational Medicine 9 (392), eaal3447, 2017 | 198 | 2017 |
| Targeting virulence not viability in the search for future antibacterials B Heras, MJ Scanlon, JL Martin British journal of clinical pharmacology 79 (2), 208-215, 2015 | 193 | 2015 |
| The three-dimensional solution structure of NaD1, a new floral defensin from Nicotiana alata and its application to a homology model of the crop defense protein alfAFP FT Lay, HJ Schirra, MJ Scanlon, MA Anderson, DJ Craik Journal of Molecular Biology 325 (1), 175-188, 2003 | 175 | 2003 |
| The cysteine-rich secretory protein domain of Tpx-1 is related to ion channel toxins and regulates ryanodine receptor Ca2+ signaling GM Gibbs, MJ Scanlon, J Swarbrick, S Curtis, E Gallant, AF Dulhunty, ... Journal of Biological Chemistry 281 (7), 4156-4163, 2006 | 162 | 2006 |
| Fatty acid-binding protein 5 facilitates the blood–brain barrier transport of docosahexaenoic acid Y Pan, MJ Scanlon, Y Owada, Y Yamamoto, CJH Porter, JA Nicolazzo Molecular pharmaceutics 12 (12), 4375-4385, 2015 | 120 | 2015 |
| Solution structure and proposed binding mechanism of a novel potassium channel toxin κ-conotoxin PVIIA MJ Scanlon, D Naranjo, L Thomas, PF Alewood, RJ Lewis, DJ Craik Structure 5 (12), 1585-1597, 1997 | 112 | 1997 |
| A Backbone Linker for BOC-Based Peptide Synthesis and On-Resin Cyclization: Synthesis of Stylostatin 1, GT Bourne, WDF Meutermans, PF Alewood, RP McGeary, M Scanlon, ... The Journal of Organic Chemistry 64 (9), 3095-3101, 1999 | 108 | 1999 |
| Difficult macrocyclizations: New strategies for synthesizing highly strained cyclic tetrapeptides WDF Meutermans, GT Bourne, SW Golding, DA Horton, MR Campitelli, ... Organic Letters 5 (15), 2711-2714, 2003 | 107 | 2003 |
| The ways and means of fragment-based drug design BC Doak, RS Norton, MJ Scanlon Pharmacology & therapeutics 167, 28-37, 2016 | 98 | 2016 |
| Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation AL Robertson, SJ Headey, HM Saunders, H Ecroyd, MJ Scanlon, ... Proceedings of the National Academy of Sciences 107 (23), 10424-10429, 2010 | 94 | 2010 |
| Promiscuous 2-aminothiazoles (PrATs): a frequent hitting scaffold SM Devine, MD Mulcair, CO Debono, EWW Leung, JWM Nissink, SS Lim, ... Journal of medicinal chemistry 58 (3), 1205-1214, 2015 | 93 | 2015 |
| Structural and functional analysis of the Josephin domain of the polyglutamine protein ataxin-3 MKM Chow, JP Mackay, JC Whisstock, MJ Scanlon, SP Bottomley Biochemical and biophysical research communications 322 (2), 387-394, 2004 | 93 | 2004 |
| Characterization of the drug binding specificity of rat liver fatty acid binding protein S Chuang, T Velkov, J Horne, CJH Porter, MJ Scanlon Journal of medicinal chemistry 51 (13), 3755-3764, 2008 | 88 | 2008 |
| The structure of the bacterial oxidoreductase enzyme DsbA in complex with a peptide reveals a basis for substrate specificity in the catalytic cycle of DsbA enzymes JJ Paxman, NA Borg, J Horne, PE Thompson, Y Chin, P Sharma, ... Journal of biological chemistry 284 (26), 17835-17845, 2009 | 83 | 2009 |
| Parallel screening of low molecular weight fragment libraries: do differences in methodology affect hit identification? J Wielens, SJ Headey, DI Rhodes, RJ Mulder, O Dolezal, JJ Deadman, ... Journal of Biomolecular Screening 18 (2), 147-159, 2013 | 81 | 2013 |
Chris PorterDirector, Monash Institute of Pharmaceutical Sciences, Monash University在 monash.edu 的电子邮件经过验证
