Super-enhancers in the control of cell identity and disease D Hnisz, BJ Abraham, TI Lee, A Lau, V Saint-André, AA Sigova, HA Hoke, ... Cell 155 (4), 934-947, 2013 | 3600 | 2013 |
A distinct small RNA pathway silences selfish genetic elements in the germline VV Vagin, A Sigova, C Li, H Seitz, V Gvozdev, PD Zamore Science 313 (5785), 320-324, 2006 | 1551 | 2006 |
Activation of proto-oncogenes by disruption of chromosome neighborhoods D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak, CH Li, J Goldmann, ... Science 351 (6280), 1454-1458, 2016 | 1079 | 2016 |
YY1 is a structural regulator of enhancer-promoter loops AS Weintraub, CH Li, AV Zamudio, AA Sigova, NM Hannett, DS Day, ... Cell 171 (7), 1573-1588. e28, 2017 | 899 | 2017 |
Revisiting global gene expression analysis J Lovén, DA Orlando, AA Sigova, CY Lin, PB Rahl, CB Burge, DL Levens, ... Cell 151 (3), 476-482, 2012 | 712 | 2012 |
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells AA Sigova, AC Mullen, B Molinie, S Gupta, DA Orlando, MG Guenther, ... Proceedings of the National Academy of Sciences 110 (8), 2876-2881, 2013 | 511 | 2013 |
Transcription factor trapping by RNA in gene regulatory elements AA Sigova, BJ Abraham, X Ji, B Molinie, NM Hannett, YE Guo, M Jangi, ... Science 350 (6263), 978-981, 2015 | 470 | 2015 |
A single Argonaute protein mediates both transcriptional and posttranscriptional silencing in Schizosaccharomyces pombe A Sigova, N Rhind, PD Zamore Genes & development 18 (19), 2359-2367, 2004 | 193 | 2004 |
Genome-wide localization of small molecules L Anders, MG Guenther, J Qi, ZP Fan, JJ Marineau, PB Rahl, J Loven, ... Nature biotechnology 32 (1), 92-96, 2014 | 190 | 2014 |
Mechanism of action of calcium ionophores on intact cells: ionophore-resistant cells EN Dedkova, AA Sigova, VP Zinchenko Membr cell biol 13 (3), 357-368, 2000 | 114 | 2000 |
The rate of protein synthesis in hematopoietic stem cells is limited partly by 4E-BPs RAJ Signer, L Qi, Z Zhao, D Thompson, AA Sigova, ZP Fan, ... Genes & development 30 (15), 1698-1703, 2016 | 98 | 2016 |
Cytoskeletal regulation of the L-arginine/NO pathway in pulmonary artery endothelial cells SI Zharikov, AA Sigova, S Chen, MR Bubb, ER Block American Journal of Physiology-Lung Cellular and Molecular Physiology 280 (3 …, 2001 | 75 | 2001 |
DIGIT is a conserved long noncoding RNA that regulates GSC expression to control definitive endoderm differentiation of embryonic stem cells K Daneshvar, JV Pondick, BM Kim, C Zhou, SR York, JA Macklin, ... Cell reports 17 (2), 353-365, 2016 | 72 | 2016 |
Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH Settings BE Schwartz, V Rajagopal, C Smith, E Cohick, G Whissell, M Gamboa, ... Cells 9 (10), 2247, 2020 | 34 | 2020 |
A comparative study of the calcium system in memory T cells and naive T cells A Sigova, E Dedkova, V Zinchenko, I Litvinov FEBS letters 447 (1), 34-38, 1999 | 28 | 1999 |
Measuring the rates of transcriptional elongation in the female Drosophila melanogaster germ line by nuclear run-on A Sigova, V Vagin, PD Zamore Cold Spring Harbor Symposia on Quantitative Biology 71, 335-341, 2006 | 10 | 2006 |
Reduction of Ca2+-transporting systems in memory T cells. AA Sigova, EN Dedkova, VP Zinchenko, IS Litvinov Membrane & Cell Biology 14 (1), 97-107, 2000 | 6 | 2000 |
Small RNA silencing pathways A Sigova, PD Zamore Antisense Drug Technology, 93-106, 2007 | 5 | 2007 |
Identification and targeted modulation of gene signaling networks Y Liu, A Sigova, CW O'donnell, C Smith, G Whissell, B Chevalier, ... US Patent App. 16/610,899, 2021 | 4 | 2021 |
Methods of altering gene expression by perturbing transcription factor multimers that structure regulatory loops RA Young, AS Weintraub, CH Li, AA Sigova US Patent 11,873,496, 2024 | 3 | 2024 |