A complex secretory program orchestrated by the inflammasome controls paracrine senescence JC Acosta, A Banito, T Wuestefeld, A Georgilis, P Janich, JP Morton, ... Nature cell biology 15 (8), 978-990, 2013 | 2005 | 2013 |
Chemokine signaling via the CXCR2 receptor reinforces senescence JC Acosta, A O'Loghlen, A Banito, MV Guijarro, A Augert, S Raguz, ... cell 133 (6), 1006-1018, 2008 | 1893 | 2008 |
Senescence impairs successful reprogramming to pluripotent stem cells A Banito, ST Rashid, JC Acosta, SD Li, CF Pereira, I Geti, S Pinho, ... Genes & development 23 (18), 2134-2139, 2009 | 722 | 2009 |
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype N Herranz, S Gallage, M Mellone, T Wuestefeld, S Klotz, CJ Hanley, ... Nature cell biology 17 (9), 1205-1217, 2015 | 680 | 2015 |
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS M Barradas, E Anderton, JC Acosta, SD Li, A Banito, ... Genes & development 23 (10), 1177-1182, 2009 | 394 | 2009 |
Senescence: a new weapon for cancer therapy JC Acosta, J Gil Trends in cell biology 22 (4), 211-219, 2012 | 277 | 2012 |
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration S Ferreira-Gonzalez, WY Lu, A Raven, B Dwyer, TY Man, E O’Duibhir, ... Nature Communications 9 (1), 1020, 2018 | 139 | 2018 |
The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype P Hari, FR Millar, N Tarrats, J Birch, A Quintanilla, CJ Rink, ... Science advances 5 (6), eaaw0254, 2019 | 130 | 2019 |
p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells MJ Muñoz-Alonso, JC Acosta, C Richard, MD Delgado, J Sedivy, J León Journal of Biological Chemistry 280 (18), 18120-18129, 2005 | 126 | 2005 |
SKP2 oncogene is a direct MYC target gene and MYC down-regulates p27KIP1 through SKP2 in human leukemia cells G Bretones, JC Acosta, JM Caraballo, N Ferrándiz, MT Gómez-Casares, ... Journal of Biological Chemistry 286 (11), 9815-9825, 2011 | 117 | 2011 |
Control of senescence by CXCR2 and its ligands JC Acosta, A Loghlen, A Banito, S Raguz, J Gil Cell cycle 7 (19), 2956-2959, 2008 | 111 | 2008 |
Suppression of autophagy impedes glioblastoma development and induces senescence N Gammoh, J Fraser, C Puente, HM Syred, H Kang, T Ozawa, D Lam, ... Autophagy 12 (9), 1431-1439, 2016 | 107 | 2016 |
A role for CXCR2 in senescence, but what about in cancer? JC Acosta, J Gil Cancer research 69 (6), 2167-2170, 2009 | 105 | 2009 |
Notch signaling mediates secondary senescence YV Teo, N Rattanavirotkul, N Olova, A Salzano, A Quintanilla, N Tarrats, ... Cell reports 27 (4), 997-1007. e5, 2019 | 97 | 2019 |
An adaptive signaling network in melanoma inflammatory niches confers tolerance to MAPK signaling inhibition HL Young, EJ Rowling, M Bugatti, E Giurisato, N Luheshi, I Arozarena, ... Journal of Experimental Medicine 214 (6), 1691-1710, 2017 | 92 | 2017 |
Inhibition of cell differentiation: a critical mechanism for MYC-mediated carcinogenesis? J Leon, N Ferrandiz, JC Acosta, MD Delgado Cell cycle 8 (8), 1148-1157, 2009 | 89 | 2009 |
Nuclear pore density controls heterochromatin reorganization during senescence C Boumendil, P Hari, KCF Olsen, JC Acosta, WA Bickmore Genes & Development 33 (3-4), 144-149, 2019 | 83 | 2019 |
Myc inhibits p27-induced erythroid differentiation of leukemia cells by repressing erythroid master genes without reversing p27-mediated cell cycle arrest JC Acosta, N Ferrándiz, G Bretones, V Torrano, R Blanco, C Richard, ... Molecular and cellular biology, 2008 | 81 | 2008 |
MYC in chronic myeloid leukemia: induction of aberrant DNA synthesis and association with poor response to imatinib M Albajar, MT Gómez-Casares, J Llorca, I Mauleon, JP Vaqué, JC Acosta, ... Molecular Cancer Research 9 (5), 564-576, 2011 | 77 | 2011 |
PHD3 regulates p53 protein stability by hydroxylating proline 359 J Rodriguez, A Herrero, S Li, N Rauch, A Quintanilla, K Wynne, A Krstic, ... Cell reports 24 (5), 1316-1329, 2018 | 70 | 2018 |