The whole-genome landscape of Burkitt lymphoma subtypes RI Panea, CL Love, JR Shingleton, A Reddy, JA Bailey, AM Moormann, ... Blood, The Journal of the American Society of Hematology 134 (19), 1598-1607, 2019 | 152 | 2019 |
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell M Puray-Chavez, KM LaPak, TP Schrank, JL Elliott, DP Bhatt, ... Cell Reports 36 (2), 2021 | 136 | 2021 |
WNT activates the AAK1 kinase to promote clathrin-mediated endocytosis of LRP6 and establish a negative feedback loop MJ Agajanian, MP Walker, AD Axtman, RR Ruela-de-Sousa, DS Serafin, ... Cell reports 26 (1), 79-93. e8, 2019 | 79 | 2019 |
PEAK1 acts as a molecular switch to regulate context-dependent TGFβ responses in breast cancer M Agajanian, A Campeau, M Hoover, A Hou, D Brambilla, SL Kim, ... PLoS One 10 (8), e0135748, 2015 | 53 | 2015 |
Identification of a PEAK1/ZEB1 signaling axis during TGFβ/fibronectin-induced EMT in breast cancer M Agajanian, F Runa, JA Kelber Biochemical and biophysical research communications 465 (3), 606-612, 2015 | 48 | 2015 |
Gain-of-function genetic screen of the kinome reveals BRSK2 as an inhibitor of the NRF2 transcription factor TY Tamir, BM Bowman, MJ Agajanian, D Goldfarb, TP Schrank, T Stohrer, ... Journal of cell science 133 (14), jcs241356, 2020 | 25 | 2020 |
A SNAI2-PEAK1-INHBA stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting subpopulations of tumor cells positive for … S Hamalian, R Güth, F Runa, F Sanchez, E Vickers, M Agajanian, ... Oncogene 40 (33), 5224-5235, 2021 | 15 | 2021 |
Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell. Cell Rep 36: 109364 M Puray-Chavez, KM LaPak, TP Schrank, JL Elliott, DP Bhatt, ... | 12 | 2021 |
Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signaling MJ Agajanian, FM Potjewyd, BM Bowman, S Solomon, KM LaPak, ... Journal of Biological Chemistry 298 (6), 2022 | 6 | 2022 |
DHPS-dependent hypusination of eIF5A1/2 is necessary for TGFβ/fibronectin-induced breast cancer metastasis and associates with prognostically unfavorable genomic alterations in … R Güth, Y Adamian, C Geller, J Molnar, J Maddela, L Kutscher, K Bhakta, ... Biochemical and biophysical research communications 519 (4), 838-845, 2019 | 6 | 2019 |
PEAK1 kinase acts as a molecular switch to mediate TGFbeta-induced EMT in breast cancer M Agajanian, A Campeau, D Brambilla, M Hoover, R Klemke, J Kelber MOLECULAR BIOLOGY OF THE CELL 25, 2014 | 1 | 2014 |
Kinase Regulation of WNT Signaling MJ Agajanian The University of North Carolina at Chapel Hill, 2021 | | 2021 |
A SNAI2-PEAK1 stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting a cytokine expression profile that converges on PI3K/Akt … S Hamalian, R Güth, F Runa, J Molnar, E Vickers, M Agajanian, ... bioRxiv, 2020.05. 15.098772, 2020 | | 2020 |
Mesenchymal stromal cells expressing a PEAK1/Cripto axis sustain pro-survival NF-κB signaling in adjacent tumor cells to promote disease progression and therapy resistance S Hamalian, R Güth, I Zervantonakis, E Duell, JR Lin, P Shisgal, J Molnar, ... Cancer Research 78 (13_Supplement), 2140-2140, 2018 | | 2018 |
AAK1 inhibits WNT signaling by promoting clathrin-mediated endocytosis of LRP6 MJ Agajanian, MP Walker, AD Axtman, RR Ruela-de-Sousa, ... bioRxiv, 258632, 2018 | | 2018 |
A Transcription-uncoupled Negative Feedback Loop for the 1 WNT Pathway: WNT Activates the AAK1 Kinase to Promote Clathrin-mediated Endocytosis of LRP6 MJ Agajanian, MP Walker, AD Axtman, RR Ruela-de-Sousa, ... | | 2018 |
The PEAK1/ZEB1/ITGA1 pathway mediates survival, stemness and TGFbeta-induced EMT in pancreatic cancer A Gharibi, SL Kim, D Brambilla, Y Adamian, M Hoover, J Lin, M Agajanian, ... Cancer Research 76 (14_Supplement), 4426-4426, 2016 | | 2016 |
ITGA1 is a novel biomarker and therapeutic target for blocking stemness in pancreatic cancer. S Kim, A Gharibi, DC Brambilla, Y Adamian, M Hoover, J Lin, M Agajanian, ... MOLECULAR BIOLOGY OF THE CELL 27, 2016 | | 2016 |
Identification of a PEAK1/ZEB1 signaling axis during TGFβ/fibronectin-induced EMT in breast cancer M Agajanian, JA Kelberauthor | | 2015 |
TGF beta-induced EMT and motility phenotypes in mammary epithelial cells M Agajanian, M Hoover, JA Kelber MOLECULAR BIOLOGY OF THE CELL 24, 2013 | | 2013 |