Cancer metabolic reprogramming: importance, main features, and potentials for precise targeted anti-cancer therapies LM Phan, SCJ Yeung, MH Lee Cancer biology & medicine 11 (1), 1, 2014 | 586 | 2014 |
Obesity-associated NLRC4 inflammasome activation drives breast cancer progression R Kolb, L Phan, N Borcherding, Y Liu, F Yuan, AM Janowski, Q Xie, ... Nature communications 7 (1), 13007, 2016 | 223 | 2016 |
Aurora B kinase phosphorylates and instigates degradation of p53 CP Gully, G Velazquez-Torres, JH Shin, E Fuentes-Mattei, E Wang, ... Proceedings of the National Academy of Sciences 109 (24), E1513-E1522, 2012 | 194 | 2012 |
Roles of COP9 signalosome in cancer MH Lee, R Zhao, L Phan, SCJ Yeung Cell cycle 10 (18), 3057-3066, 2011 | 162 | 2011 |
Analysis of genomes and transcriptomes of hepatocellular carcinomas identifies mutations and gene expression changes in the transforming growth factor-β pathway J Chen, S Zaidi, S Rao, JS Chen, L Phan, P Farci, X Su, K Shetty, J White, ... Gastroenterology 154 (1), 195-210, 2018 | 127 | 2018 |
Effects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor–positive breast cancer E Fuentes-Mattei, G Velazquez-Torres, L Phan, F Zhang, PC Chou, ... JNCI: Journal of the National Cancer Institute 106 (7), dju158, 2014 | 122 | 2014 |
A hypoxia-responsive TRAF6–ATM–H2AX signalling axis promotes HIF1α activation, tumorigenesis and metastasis AH Rezaeian, CF Li, CY Wu, X Zhang, J Delacerda, MJ You, F Han, Z Cai, ... Nature Cell Biology, 2016 | 103 | 2016 |
Kinetic modeling and constrained reconstruction of hyperpolarized [1-13C]-pyruvate offers improved metabolic imaging of tumors CM Walker, MS Ramirez, W Stefan, D Fuentes, ME Merritt, J Lee, ... Cancer Research, 2015 | 103 | 2015 |
CSN6 drives carcinogenesis by positively regulating Myc stability J Chen, JH Shin, R Zhao, L Phan, H Wang, Y Xue, SM Post, H Ho Choi, ... Nature communications 5 (1), 5384, 2014 | 74 | 2014 |
p53 negatively regulates Aurora A via both transcriptional and posttranslational regulation CC Wu, TY Yang, CTR Yu, L Phan, C Ivan, AK Sood, SL Hsu, MH Lee Cell cycle 11 (18), 3433-3442, 2012 | 74 | 2012 |
The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming L Phan, PC Chou, G Velazquez-Torres, I Samudio, K Parreno, Y Huang, ... Nature communications 6 (1), 7530, 2015 | 73 | 2015 |
COP9 signalosome subunit 6 stabilizes COP1, which functions as an E3 ubiquitin ligase for 14-3-3σ HH Choi, C Gully, CH Su, G Velazquez-Torres, PC Chou, C Tseng, ... Oncogene 30 (48), 4791-4801, 2011 | 73 | 2011 |
14-3-3σ exerts tumor-suppressor activity mediated by regulation of COP1 stability CH Su, R Zhao, F Zhang, C Qu, B Chen, YH Feng, L Phan, J Chen, ... Cancer research 71 (3), 884-894, 2011 | 68 | 2011 |
Hepatocyte growth factor/cMET pathway activation enhances cancer hallmarks in adrenocortical carcinoma LM Phan, E Fuentes-Mattei, W Wu, G Velazquez-Torres, K Sircar, ... Cancer Research, 2015 | 57 | 2015 |
FBXW7 is involved in Aurora B degradation CL Teng, YC Hsieh, L Phan, J Shin, C Gully, G Velazquez-Torres, S Skerl, ... Cell cycle 11 (21), 4059-4068, 2012 | 57 | 2012 |
TRIM24 links glucose metabolism with transformation of human mammary epithelial cells TN Pathiraja, KN Thakkar, S Jiang, S Stratton, Z Liu, M Gagea, X Shi, ... Oncogene 34 (22), 2836-2845, 2015 | 56 | 2015 |
COP1 enhances ubiquitin-mediated degradation of p27Kip1 to promote cancer cell growth HH Choi, L Phan, PC Chou, CH Su, SCJ Yeung, JS Chen, MH Lee Oncotarget 6 (23), 19721, 2015 | 55 | 2015 |
CDK inhibitor p57Kip2 is downregulated by Akt during HER2-mediated tumorigenicity R Zhao, HY Yang, J Shin, L Phan, L Fang, TF Che, CH Su, SCJ Yeung, ... Cell cycle 12 (6), 935-943, 2013 | 48 | 2013 |
CDK inhibitor p57Kip2 is negatively regulated by COP9 signalosome subunit 6 B Chen, R Zhao, CH Su, M Linan, C Tseng, L Phan, L Fang, HY Yang, ... Cell cycle 11 (24), 4633-4641, 2012 | 47 | 2012 |
ATM: Main Features, Signaling Pathways, and Its Diverse Roles in DNA Damage Response, Tumor Suppression, and Cancer Development LM Phan, AH Rezaeian Genes 12 (6), 845, 2021 | 46 | 2021 |