Peptidylarginine deiminase 2 is required for tumor necrosis factor alpha-induced citrullination and arthritis, but not neutrophil extracellular trap formation M Bawadekar, D Shim, CJ Johnson, TF Warner, R Rebernick, ... Journal of autoimmunity 80, 39-47, 2017 | 91 | 2017 |
Demonstration of extracellular peptidylarginine deiminase (PAD) activity in synovial fluid of patients with rheumatoid arthritis using a novel assay for citrullination of … D Damgaard, L Senolt, MF Nielsen, GJ Pruijn, CH Nielsen Arthritis research & therapy 16, 1-7, 2014 | 90 | 2014 |
Reduced glutathione as a physiological co-activator in the activation of peptidylarginine deiminase D Damgaard, ME Bjørn, MA Steffensen, GJM Pruijn, CH Nielsen Arthritis research & therapy 18, 1-7, 2016 | 63 | 2016 |
Increased levels of peptidylarginine deiminase 2 in synovial fluid from anti-CCP-positive rheumatoid arthritis patients: Association with disease activity and inflammatory markers D Damgaard, L Senolt, CH Nielsen Rheumatology 55 (5), 918-927, 2016 | 57 | 2016 |
Smoking is associated with increased levels of extracellular peptidylarginine deiminase 2 (PAD2) in the lungs D Damgaard, MFB Nielsen, MQ Gaunsbaek, Y Palarasah, ... Clin Exp Rheumatol 33 (3), 405-408, 2015 | 51 | 2015 |
Calgizzarin (S100A11): a novel inflammatory mediator associated with disease activity of rheumatoid arthritis L Andrés Cerezo, B Šumová, K Prajzlerová, D Veigl, D Damgaard, ... Arthritis research & therapy 19, 1-10, 2017 | 45 | 2017 |
Reactive oxygen species inhibit catalytic activity of peptidylarginine deiminase D Damgaard, ME Bjørn, PØ Jensen, CH Nielsen Journal of Enzyme Inhibition and Medicinal Chemistry 32 (1), 1203-1208, 2017 | 38 | 2017 |
Relative efficiencies of peptidylarginine deiminase 2 and 4 in generating target sites for anti-citrullinated protein antibodies in fibrinogen, alpha-enolase and histone H3 D Damgaard, M Bawadekar, L Senolt, A Stensballe, MA Shelef, ... PLoS One 13 (8), e0203214, 2018 | 37 | 2018 |
Citrullination of fibrinogen by peptidylarginine deiminase 2 impairs fibrin clot structure T Damiana, D Damgaard, JJ Sidelmann, CH Nielsen, MPM de Maat, ... Clinica chimica acta 501, 6-11, 2020 | 32 | 2020 |
Friberg Bruun Nielsen M, Quisgaard Gaunsbaek M, Palarasah Y, Svane-Knudsen V, Nielsen CH. Smoking is associated with increased levels of extracellular peptidylarginine … D Damgaard Clin Exp Rheumatol 33 (3), 405-8, 2015 | 29 | 2015 |
Applicability of small-molecule inhibitors in the study of peptidyl arginine deiminase 2 (PAD2) and PAD4 MT Martín Monreal, AS Rebak, L Massarenti, S Mondal, L Šenolt, N Ødum, ... Frontiers in Immunology 12, 716250, 2021 | 24 | 2021 |
S100A11 (calgizzarin) is released via NETosis in rheumatoid arthritis (RA) and stimulates IL-6 and TNF secretion by neutrophils A Navrátilová, V Bečvář, J Baloun, D Damgaard, CH Nielsen, D Veigl, ... Scientific reports 11 (1), 6063, 2021 | 24 | 2021 |
Peptidylarginine deiminase-4 gene polymorphisms are associated with systemic lupus erythematosus and lupus nephritis L Massarenti, C Enevold, D Damgaard, N Ødum, CH Nielsen, S Jacobsen Scandinavian journal of rheumatology 48 (2), 133-140, 2019 | 23 | 2019 |
Expanding the citrullinome of synovial fibrinogen from rheumatoid arthritis patients M Sharma, D Damgaard, L Senolt, B Svensson, AC Bay-Jensen, ... Journal of proteomics 208, 103484, 2019 | 22 | 2019 |
Identification of novel native autoantigens in rheumatoid arthritis TBG Poulsen, D Damgaard, MM Jørgensen, L Senolt, JM Blackburn, ... Biomedicines 8 (6), 141, 2020 | 19 | 2020 |
PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking L Massarenti, C Enevold, D Damgaard, N Ødum, P Garred, M Frisch, ... Frontiers in immunology 12, 707690, 2021 | 13 | 2021 |
Release of active peptidylarginine deiminase into the circulation during acute inflammation induced by coronary artery bypass surgery A Vejlstrup, AM Møller, CH Nielsen, D Damgaard Journal of Inflammation Research, 137-144, 2019 | 12 | 2019 |
Generation of monoclonal antibodies against peptidylarginine deiminase 2 (PAD2) and development of a PAD2-specific enzyme-linked immunosorbent assay D Damgaard, Y Palarasah, K Skjødt, AI Catrina, SMM Hensen, GJM Pruijn, ... Journal of Immunological Methods 405, 15-22, 2014 | 12 | 2014 |
Identification of potential autoantigens in anti-CCP-positive and anti-CCP-negative rheumatoid arthritis using citrulline-specific protein arrays TBG Poulsen, D Damgaard, MM Jørgensen, L Senolt, JM Blackburn, ... Scientific Reports 11 (1), 17300, 2021 | 8 | 2021 |
Anti-pad2 antibodies and treatment of autoimmune diseases CH Nielsen, D Damgaard US Patent App. 14/649,100, 2015 | 5 | 2015 |