Euler‐Lagrange computational fluid dynamics for (bio) reactor scale down: an analysis of organism lifelines C Haringa, W Tang, AT Deshmukh, J Xia, M Reuss, JJ Heijnen, ... Engineering in life sciences 16 (7), 652-663, 2016 | 135 | 2016 |
Computational fluid dynamics simulation of an industrial P. chrysogenum fermentation with a coupled 9-pool metabolic model: Towards rational scale-down and design optimization C Haringa, W Tang, G Wang, AT Deshmukh, WA van Winden, J Chu, ... Chemical Engineering Science 175, 12-24, 2018 | 119 | 2018 |
Euler-Lagrange analysis towards representative down-scaling of a 22 m3 aerobic S. cerevisiae fermentation C Haringa, AT Deshmukh, RF Mudde, HJ Noorman Chemical Engineering Science 170, 653-669, 2017 | 108 | 2017 |
Scale‐down of penicillin production in Penicillium chrysogenum LP de Jonge, NAA Buijs, A ten Pierick, A Deshmukh, Z Zhao, JAKW Kiel, ... Biotechnology journal 6 (8), 944-958, 2011 | 96 | 2011 |
Quantitative analysis of intracellular coenzymes in Saccharomyces cerevisiae using ion pair reversed phase ultra high performance liquid chromatography tandem mass spectrometry RM Seifar, C Ras, AT Deshmukh, KM Bekers, CA Suarez-Mendez, ... Journal of chromatography A 1311, 115-120, 2013 | 66 | 2013 |
A 9‐pool metabolic structured kinetic model describing days to seconds dynamics of growth and product formation by Penicillium chrysogenum W Tang, AT Deshmukh, C Haringa, G Wang, W van Gulik, W van Winden, ... Biotechnology and Bioengineering 114 (8), 1733-1743, 2017 | 61 | 2017 |
Cell physiology rather than enzyme kinetics can determine the efficiency of cytochrome P450-catalyzed C–H-oxyfunctionalization S Cornelissen, S Liu, AT Deshmukh, A Schmid, B Bühler Journal of Industrial Microbiology and Biotechnology 38 (9), 1359-1370, 2011 | 39 | 2011 |
Comparative performance of different scale‐down simulators of substrate gradients in Penicillium chrysogenum cultures: the need of a biological systems response … G Wang, J Zhao, C Haringa, W Tang, J Xia, J Chu, Y Zhuang, S Zhang, ... Microbial Biotechnology 11 (3), 486-497, 2018 | 35 | 2018 |
Novel insights in transport mechanisms and kinetics of phenylacetic acid and penicillin‐G in Penicillium chrysogenum RD Douma, AT Deshmukh, LP de Jonge, BW de Jong, RM Seifar, ... Biotechnology progress 28 (2), 337-348, 2012 | 26 | 2012 |
Power input effects on degeneration in prolonged penicillin chemostat cultures: A systems analysis at flux, residual glucose, metabolite, and transcript levels G Wang, B Wu, J Zhao, C Haringa, J Xia, J Chu, Y Zhuang, S Zhang, ... Biotechnology and Bioengineering 115 (1), 114-125, 2018 | 24 | 2018 |
In vivo kinetic analysis of the penicillin biosynthesis pathway using PAA stimulus response experiments AT Deshmukh, PJT Verheijen, RM Seifar, JJ Heijnen, WM van Gulik Metabolic Engineering 32, 155-173, 2015 | 17 | 2015 |
Determination of δ‐[L‐α‐aminoadipyl]‐L‐cysteinyl‐D‐valine in cell extracts of Penicillium chrysogenum using ion pair‐RP‐UPLC‐MS/MS RM Seifar, AT Deshmukh, JJ Heijnen, WM Van Gulik Journal of separation science 35 (2), 225-230, 2012 | 6 | 2012 |
Monitoring Intracellular Metabolite Dynamics in Saccharomyces cerevisiae during Industrially Relevant Famine Stimuli S Minden, M Aniolek, C Sarkizi Shams Hajian, A Teleki, T Zerrer, ... Metabolites 12 (3), 263, 2022 | 5 | 2022 |
Elucidation and modeling of the in-vivo kinetics of enzymes and membrane transporters associated with β-lactam and non-ribosomal peptide production in Penicillium chrysogenum AT Deshmukh | 1 | 2013 |
Towards rational design and scale up of aerobic industrial fermentations: P. chrysogenum as model organism A Deshmukh, W van Winden, H Noorman, C Haringa, R Mudde, ... 2016 SIMB Annual Meeting and Exhibition, 2016 | | 2016 |
Elucidation and modeling of the in-vivo kinetics of enzymes and membrane transporters associated with b-lactam and non-ribosomal ppetide production in Penicillium chrysogenum AT Deshmukh | | 2013 |
Resolving Phenylalanine Metabolism Sheds Light on Natural Synthesis of Penicillin G in Penicillium chrysogenum (vol 11, pg 238, 2012) T Veiga, D Solis-Escalante, G Romagnoli, A ten Pierick, M Hanemaaijer, ... EUKARYOTIC CELL 12 (1), 151-151, 2013 | | 2013 |
La-aminoadipate is not the limiting precursor aminoacid in the penicillin biosynthetic pathway in a high producing P. chrysogenum strain AT Deshmukh, C van der Hoek, RM Seifar, A ten Pierick, JJ Heijnen, ... Poster: Proces Technology Symposium, 2012 | | 2012 |
Unraveling in vivo kinetics of penicillin biosyntheses pathway AT Deshmukh, PJT Verheijen, RM Seifar, JJ Heijnen, WM van Gulik Poster: Metabolic Engineering IX, 2012 | | 2012 |
Understanding in-vivo kinetics and transport through stimulus response experiments Penicillium chrysogenum as host strain A Deshmukh | | 2012 |