Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell- and patient-derived tumor organoids. L Huang, A Holtzinger, I Jagan, M BeGora, I Lohse, N Ngai, C Nostro, ... Nat Med 21 (11), 1364-71, 2015 | 733 | 2015 |
Stage-specific signaling through TGFβ family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells MC Nostro, F Sarangi, S Ogawa, A Holtzinger, B Corneo, X Li, SJ Micallef, ... Development 138 (5), 861-871, 2011 | 487 | 2011 |
Generation of anterior foregut endoderm from human embryonic and induced pluripotent stem cells MD Green, A Chen, MC Nostro, SL d'Souza, C Schaniel, IR Lemischka, ... Nature biotechnology 29 (3), 267-272, 2011 | 449 | 2011 |
Wnt, activin, and BMP signaling regulate distinct stages in the developmental pathway from embryonic stem cells to blood MC Nostro, X Cheng, GM Keller, P Gadue Cell stem cell 2 (1), 60-71, 2008 | 394 | 2008 |
Efficient generation of NKX6-1+ pancreatic progenitors from multiple human pluripotent stem cell lines MC Nostro, F Sarangi, C Yang, A Holland, AG Elefanty, EG Stanley, ... Stem cell reports 4 (4), 591-604, 2015 | 334 | 2015 |
Self-renewing endodermal progenitor lines generated from human pluripotent stem cells X Cheng, L Ying, L Lu, AM Galvão, JA Mills, HC Lin, DN Kotton, SS Shen, ... Cell stem cell 10 (4), 371-384, 2012 | 300 | 2012 |
Germ layer induction from embryonic stem cells P Gadue, TL Huber, MC Nostro, S Kattman, GM Keller Experimental hematology 33 (9), 955-964, 2005 | 190 | 2005 |
The functional and molecular characterisation of human embryonic stem cell-derived insulin-positive cells compared with adult pancreatic beta cells CL Basford, KJ Prentice, AB Hardy, F Sarangi, SJ Micallef, X Li, Q Guo, ... Diabetologia 55, 358-371, 2012 | 160 | 2012 |
INS GFP/w human embryonic stem cells facilitate isolation of in vitro derived insulin-producing cells SJ Micallef, X Li, JV Schiesser, CE Hirst, QC Yu, SM Lim, MC Nostro, ... Diabetologia 55, 694-706, 2012 | 152 | 2012 |
Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors KF Cogger, A Sinha, F Sarangi, EC McGaugh, D Saunders, C Dorrell, ... Nature communications 8 (1), 331, 2017 | 130 | 2017 |
Generation of beta cells from human pluripotent stem cells: potential for regenerative medicine MC Nostro, G Keller Seminars in cell & developmental biology 23 (6), 701-710, 2012 | 123 | 2012 |
Directed differentiation of pluripotent stem cells: from developmental biology to therapeutic applications S Irion, MC Nostro, SJ Kattman, GM Keller Cold Spring Harbor symposia on quantitative biology 73, 101-110, 2008 | 116 | 2008 |
Bcl-w expression in colorectal adenocarcinoma. J Wilson, MC Nostro, M Balzi, P Faraoni, F Cianchi, A Becciolini, C Potten 2000 82 (1), 178-85, 2000 | 93 | 2000 |
Cell therapy for type 1 diabetes: current and future strategies Y Aghazadeh, MC Nostro Current diabetes reports 17, 1-9, 2017 | 83 | 2017 |
Report of the key opinion leaders meeting on stem cell-derived beta cells J Odorico, J Markmann, D Melton, J Greenstein, A Hwa, C Nostro, ... Transplantation 102 (8), 1223-1229, 2018 | 80 | 2018 |
Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models Y Aghazadeh, F Poon, F Sarangi, FTM Wong, ST Khan, X Sun, R Hatkar, ... Cell Stem Cell 28 (11), 1936-1949. e8, 2021 | 64 | 2021 |
Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics MD Ungrin, G Clarke, T Yin, S Niebrugge, MC Nostro, F Sarangi, G Wood, ... Biotechnology and Bioengineering 109 (4), 853-866, 2012 | 61 | 2012 |
Notch Signaling Induces Apoptosis in Primary Human CD34+ Hematopoietic Progenitor Cells N Chadwick, MC Nostro, M Baron, R Mottram, G Brady, AM Buckle Stem Cells 25 (1), 203-210, 2007 | 60 | 2007 |
A systems biology approach to Down syndrome: identification of Notch/Wnt dysregulation in a model of stem cells aging CJ Cairney, G Sanguinetti, E Ranghini, AD Chantry, MC Nostro, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1792 (4), 353-363, 2009 | 57 | 2009 |
Human pluripotent stem cell-derived insulin-producing cells: A regenerative medicine perspective A Migliorini, MC Nostro, JB Sneddon Cell metabolism 33 (4), 721-731, 2021 | 51 | 2021 |