The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers BM Baker, AO Gee, RB Metter, AS Nathan, RA Marklein, JA Burdick, ... Biomaterials 29 (15), 2348-2358, 2008 | 761 | 2008 |
Spatially controlled hydrogel mechanics to modulate stem cell interactions RA Marklein, JA Burdick Soft Matter 6 (1), 136-143, 2010 | 325 | 2010 |
Controlling stem cell fate with material design RA Marklein, JA Burdick Advanced materials 22 (2), 175-189, 2010 | 294 | 2010 |
Morphological features of IFN-γ–stimulated mesenchymal stromal cells predict overall immunosuppressive capacity MW Klinker, RA Marklein, JL Lo Surdo, CH Wei, SR Bauer Proceedings of the National Academy of Sciences 114 (13), E2598-E2607, 2017 | 187 | 2017 |
Homogeneous and organized differentiation within embryoid bodies induced by microsphere-mediated delivery of small molecules RL Carpenedo, AM Bratt-Leal, RA Marklein, SA Seaman, NJ Bowen, ... Biomaterials 30 (13), 2507-2515, 2009 | 175 | 2009 |
High content imaging of early morphological signatures predicts long term mineralization capacity of human mesenchymal stem cells upon osteogenic induction RA Marklein, JL Lo Surdo, IH Bellayr, SA Godil, RK Puri, SR Bauer Stem Cells 34 (4), 935-947, 2016 | 90 | 2016 |
Morphological profiling using machine learning reveals emergent subpopulations of interferon-γ–stimulated mesenchymal stromal cells that predict immunosuppression RA Marklein, MW Klinker, KA Drake, HG Polikowsky, EC Lessey-Morillon, ... Cytotherapy 21 (1), 17-31, 2019 | 72 | 2019 |
Magnitude and presentation of mechanical signals influence adult stem cell behavior in 3-dimensional macroporous hydrogels RA Marklein, DE Soranno, JA Burdick Soft Matter 8 (31), 8113-8120, 2012 | 64 | 2012 |
Functionally-relevant morphological profiling: a tool to assess cellular heterogeneity RA Marklein, J Lam, M Guvendiren, KE Sung, SR Bauer Trends in biotechnology 36 (1), 105-118, 2018 | 58 | 2018 |
Photocleavable side groups to spatially alter hydrogel properties and cellular interactions VV Ramanan, JS Katz, M Guvendiren, ER Cohen, RA Marklein, ... Journal of Materials Chemistry 20 (40), 8920-8926, 2010 | 46 | 2010 |
Functional profiling of chondrogenically induced multipotent stromal cell aggregates reveals transcriptomic and emergent morphological phenotypes predictive of differentiation … J Lam, IH Bellayr, RA Marklein, SR Bauer, RK Puri, KE Sung Stem cells translational medicine 7 (9), 664-675, 2018 | 31 | 2018 |
Priming of MSCs with inflammation-relevant signals affects extracellular vesicle biogenesis, surface markers, and modulation of T cell subsets S Andrews, T Maughon, R Marklein, S Stice Journal of immunology and regenerative medicine 13, 100036, 2021 | 25 | 2021 |
Identification of predictive gene markers for multipotent stromal cell proliferation IH Bellayr, RA Marklein, JL Lo Surdo, SR Bauer, RK Puri Stem Cells and Development 25 (11), 861-873, 2016 | 22 | 2016 |
Metabolomics and cytokine profiling of mesenchymal stromal cells identify markers predictive of T-cell suppression TS Maughon, X Shen, D Huang, AOA Michael, WA Shockey, SH Andrews, ... Cytotherapy 24 (2), 137-148, 2022 | 17 | 2022 |
Morphological landscapes from high content imaging reveal cytokine priming strategies that enhance mesenchymal stromal cell immunosuppression SH Andrews, MW Klinker, SR Bauer, RA Marklein Biotechnology and bioengineering 119 (2), 361-375, 2022 | 13 | 2022 |
Adaptation of a simple microfluidic platform for high-dimensional quantitative morphological analysis of human mesenchymal stromal cells on polystyrene-based substrates J Lam, RA Marklein, JA Jimenez-Torres, DJ Beebe, SR Bauer, KE Sung SLAS TECHNOLOGY: Translating Life Sciences Innovation 22 (6), 646-661, 2017 | 13 | 2017 |
Cross-linked polymer network formed by sequential cross-linking JA Burdick, SK Khetan, RA Marklein US Patent App. 13/059,125, 2011 | 9 | 2011 |
Human pluripotent stem cell-derived functional sympathetic neurons express ACE2 and RAAS components: a framework for studying the effect of COVID-19 on sympathetic responsiveness HF Wu, CW Huang, KR Daga, RA Marklein, N Ivanova, N Zeltner Clinical Autonomic Research 32 (1), 59-63, 2022 | 5 | 2022 |
Engineering the 3D microenvironment of embryonic stem cells undergoing differentiation TC McDevitt, RL Carpenedo, CY Sargent, GY Berguig, RA Marklein, ... Bio-Medical Materials and Engineering 18 (4), 179, 2008 | 3 | 2008 |
Development of a robust consensus modeling approach for identifying cellular and media metabolites predictive of mesenchymal stromal cell potency A Van Grouw, MB Colonna, TS Maughon, X Shen, AM Larey, SG Moore, ... Stem Cells 41 (8), 792-808, 2023 | 2 | 2023 |