Sorafenib kills liver cancer cells by disrupting SCD1‐mediated synthesis of monounsaturated fatty acids via the ATP‐AMPK‐mTOR‐SREBP1 signaling pathway G Liu, S Kuang, R Cao, J Wang, Q Peng, C Sun The FASEB Journal 33 (9), 10089-10103, 2019 | 104 | 2019 |
Whole exome sequencing identified a homozygous novel variant in CEP290 gene causes Meckel syndrome R Zhang, S Chen, P Han, F Chen, S Kuang, Z Meng, J Liu, R Sun, Z Wang, ... Journal of Cellular and Molecular Medicine 24 (2), 1906-1916, 2020 | 76 | 2020 |
Identification and functional characterization of mutations in LPL gene causing severe hypertriglyceridaemia and acute pancreatitis P Han, G Wei, K Cai, X Xiang, WP Deng, YB Li, S Kuang, Z Dong, ... Journal of Cellular and Molecular Medicine 24 (2), 1286-1299, 2020 | 75 | 2020 |
A novel polysaccharide from Sargassum integerrimum induces apoptosis in A549 cells and prevents angiogensis in vitro and in vivo G Liu, S Kuang, S Wu, W Jin, C Sun Scientific reports 6 (1), 26722, 2016 | 65 | 2016 |
Antagonistic activity and mode of action of phenazine-1-carboxylic acid, produced by marine bacterium Pseudomonas aeruginosa PA31x, against Vibrio anguillarum in vitro and in a … L Zhang, X Tian, S Kuang, G Liu, C Zhang, C Sun Frontiers in microbiology 8, 289, 2017 | 60 | 2017 |
The natural compound GL22, isolated from Ganoderma mushrooms, suppresses tumor growth by altering lipid metabolism and triggering cell death G Liu, K Wang, S Kuang, R Cao, L Bao, R Liu, H Liu, C Sun Cell Death & Disease 9 (6), 689, 2018 | 44 | 2018 |
Wedelolactone, a naturally occurring coumestan, enhances interferon-γ signaling through inhibiting STAT1 protein dephosphorylation Z Chen, X Sun, S Shen, H Zhang, X Ma, J Liu, S Kuang, Q Yu Journal of Biological Chemistry 288 (20), 14417-14427, 2013 | 43 | 2013 |
Cucurbitacin I inhibits STAT3, but enhances STAT1 signaling in human cancer cells in vitro through disrupting actin filaments H Guo, S Kuang, Q Song, M Liu, X Sun, Q Yu Acta Pharmacologica Sinica 39 (3), 425-437, 2018 | 40 | 2018 |
A novel sulfonamide agent, MPSP-001, exhibits potent activity against human cancer cells in vitro through disruption of microtubule Z Liu, W Tian, Y Wang, S Kuang, X Luo, Q Yu Acta Pharmacologica Sinica 33 (2), 261-270, 2012 | 38 | 2012 |
Bigelovin inhibits STAT3 signaling by inactivating JAK2 and induces apoptosis in human cancer cells H Zhang, S Kuang, Y Wang, X Sun, Y Gu, L Hu, Q Yu Acta Pharmacologica Sinica 36 (4), 507-516, 2015 | 31 | 2015 |
Marine bacterial polysaccharide EPS11 inhibits cancer cell growth via blocking cell adhesion and stimulating anoikis R Cao, W Jin, Y Shan, J Wang, G Liu, S Kuang, C Sun Marine Drugs 16 (3), 85, 2018 | 28 | 2018 |
Small-molecule STAT3 signaling pathway modulators from Polygonum cuspidatum J Liu, Q Zhang, K Chen, J Liu, S Kuang, W Chen, Q Yu Planta medica 78 (14), 1568-1570, 2012 | 28 | 2012 |
2‐Methoxystypandrone inhibits signal transducer and activator of transcription 3 and nuclear factor‐κB signaling by inhibiting Janus kinase 2 and IκB kinase S Kuang, C Qi, J Liu, X Sun, Q Zhang, Z Sima, J Liu, W Li, Q Yu Cancer Science 105 (4), 473-480, 2014 | 26 | 2014 |
Mansouramycin C kills cancer cells through reactive oxygen species production mediated by opening of mitochondrial permeability transition pore S Kuang, G Liu, R Cao, L Zhang, Q Yu, C Sun Oncotarget 8 (61), 104057, 2017 | 16 | 2017 |
Comparative analysis of clonal evolution among patients with right-and left-sided colon and rectal cancer S Banerjee, X Zhang, S Kuang, J Wang, L Li, G Fan, Y Luo, S Sun, P Han, ... Iscience 24 (7), 2021 | 13 | 2021 |
Family-based whole genome sequencing identified novel variants in ABCA5 gene in a patient with idiopathic ventricular tachycardia Z Du, S Kuang, Y Li, P Han, J Liu, Z Wang, Y Huang, Y Guan, X Xu, X Liu, ... Pediatric Cardiology 41, 1783-1794, 2020 | 6 | 2020 |
Synthesis of biotinylated 2-methoxystypandrone and identification of JAK2 and IKK as its targets S Kuang, Z Sima, J Liu, W Li, Q Song, Q Zhang, Q Yu Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2018 | 5 | 2018 |
Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function MM Swamynathan, S Kuang, KE Watrud, MR Doherty, C Gineste, ... Science 386 (6720), eadk9167, 2024 | 2 | 2024 |