A multifunctional bispecific antibody protects against Pseudomonas aeruginosa A DiGiandomenico, AE Keller, C Gao, GJ Rainey, P Warrener, ... Science translational medicine 6 (262), 262ra155-262ra155, 2014 | 285 | 2014 |
Patrolling alveolar macrophages conceal bacteria from the immune system to maintain homeostasis AS Neupane, M Willson, AK Chojnacki, FVES Castanheira, C Morehouse, ... Cell 183 (1), 110-125. e11, 2020 | 210 | 2020 |
Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening A Digiandomenico, P Warrener, M Hamilton, S Guillard, P Ravn, R Minter, ... Journal of Experimental Medicine 209 (7), 1273-1287, 2012 | 195 | 2012 |
Neutrophil extracellular traps confine Pseudomonas aeruginosa ocular biofilms and restrict brain invasion A Thanabalasuriar, BNV Scott, M Peiseler, ME Willson, Z Zeng, ... Cell host & microbe 25 (4), 526-536. e4, 2019 | 157 | 2019 |
A novel anti-PcrV antibody providing enhanced protection against Pseudomonas aeruginosa in multiple animal infection models P Warrener, R Varkey, JC Bonnell, A DiGiandomenico, M Camara, ... Antimicrobial agents and chemotherapy 58 (8), 4384-4391, 2014 | 130 | 2014 |
Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections TS Cohen, JJ Hilliard, O Jones-Nelson, AE Keller, T O’Day, C Tkaczyk, ... Science Translational Medicine 8 (329), 329ra31-329ra31, 2016 | 116 | 2016 |
Phase 1 study of MEDI3902, an investigational anti–Pseudomonas aeruginosa PcrV and Psl bispecific human monoclonal antibody, in healthy adults SO Ali, XQ Yu, GJ Robbie, Y Wu, K Shoemaker, L Yu, A DiGiandomenico, ... Clinical microbiology and infection 25 (5), 629. e1-629. e6, 2019 | 114 | 2019 |
Glycosylation of Pseudomonas aeruginosa 1244 pilin: glycan substrate specificity A DiGiandomenico, MJ Matewish, A Bisaillon, JR Stehle, JS Lam, ... Molecular microbiology 46 (2), 519-530, 2002 | 111 | 2002 |
Antibacterial monoclonal antibodies: the next generation? A DiGiandomenico, BR Sellman Current opinion in microbiology 27, 78-85, 2015 | 108 | 2015 |
Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature A Thanabalasuriar, BGJ Surewaard, ME Willson, AS Neupane, CK Stover, ... The Journal of clinical investigation 127 (6), 2249-2261, 2017 | 90 | 2017 |
Intranasal immunization with heterologously expressed polysaccharide protects against multiple Pseudomonas aeruginosa infections A DiGiandomenico, J Rao, K Harcher, TS Zaidi, J Gardner, AN Neely, ... Proceedings of the National Academy of Sciences 104 (11), 4624-4629, 2007 | 89 | 2007 |
Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae ME Pennini, A De Marco, M Pelletier, J Bonnell, R Cvitkovic, ... Nature communications 8 (1), 1991, 2017 | 82 | 2017 |
Suppression of acute lung inflammation by intracellular peptide delivery of a nuclear import inhibitor D Liu, J Zienkiewicz, A DiGiandomenico, J Hawiger Molecular Therapy 17 (5), 796-802, 2009 | 82 | 2009 |
Oral Vaccination of BALB/c Mice with Salmonella enterica Serovar Typhimurium Expressing Pseudomonas aeruginosa O Antigen Promotes Increased Survival in … A DiGiandomenico, J Rao, JB Goldberg Infection and immunity 72 (12), 7012-7021, 2004 | 81 | 2004 |
An engineered bispecific DNA-encoded IgG antibody protects against Pseudomonas aeruginosa in a pneumonia challenge model A Patel, A DiGiandomenico, AE Keller, TRF Smith, DH Park, S Ramos, ... Nature communications 8 (1), 637, 2017 | 61 | 2017 |
Lipopolysaccharide O-Antigen Chain Length Regulation in Pseudomonas aeruginosa Serogroup O11 Strain PA103 E Kintz, JM Scarff, A DiGiandomenico, JB Goldberg Journal of bacteriology 190 (8), 2709-2716, 2008 | 55 | 2008 |
Pseudomonas aeruginosa PcrV and Psl, the Molecular Targets of Bispecific Antibody MEDI3902, Are Conserved Among Diverse Global Clinical Isolates DE Tabor, V Oganesyan, AE Keller, L Yu, RE McLaughlin, E Song, ... The Journal of Infectious Diseases 218 (12), 1983-1994, 2018 | 54 | 2018 |
Anti-Psl Targeting of Pseudomonas aeruginosa Biofilms for Neutrophil-Mediated Disruption VA Ray, PJ Hill, CK Stover, S Roy, CK Sen, L Yu, DJ Wozniak, ... Scientific reports 7 (1), 16065, 2017 | 47 | 2017 |
Synthetic Enterobacterial Common Antigen (ECA) for the Development of a Universal Immunotherapy for Drug‐Resistant Enterobacteriaceae L Liu, J Zha, A DiGiandomenico, D McAllister, CK Stover, Q Wang, ... Angewandte Chemie 127 (37), 11103-11107, 2015 | 44 | 2015 |
Comparisons of Two Proteomic Analyses of Non-Mucoid and Mucoid Pseudomonas aeruginosa Clinical Isolates from a Cystic Fibrosis Patient J Rao, FH Damron, M Basler, A DiGiandomenico, NE Sherman, JW Fox, ... Frontiers in microbiology 2, 162, 2011 | 44 | 2011 |