| The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron S Ichikawa, HA Flaxman, W Xu, N Vallavoju, HC Lloyd, B Wang, D Shen, ... Nature 610 (7933), 775-782, 2022 | 94 | 2022 |
| A binding site hotspot map of the FKBP12–rapamycin–FRB ternary complex by photoaffinity labeling and mass spectrometry-based proteomics HA Flaxman, CF Chang, HY Wu, CH Nakamoto, CM Woo Journal of the American Chemical Society 141 (30), 11759-11764, 2019 | 48 | 2019 |
| Development of photolenalidomide for cellular target identification Z Lin, Y Amako, F Kabir, HA Flaxman, B Budnik, CM Woo Journal of the American Chemical Society 144 (1), 606-614, 2022 | 32 | 2022 |
| Biochemical and functional evaluation of the intramolecular disulfide bonds in the zinc-chelating antimicrobial protein human S100A7 (psoriasin) LS Cunden, MB Brophy, GE Rodriguez, HA Flaxman, EM Nolan Biochemistry 56 (43), 5726-5738, 2017 | 31 | 2017 |
| Mapping the small molecule interactome by mass spectrometry HA Flaxman, CM Woo Biochemistry 57 (2), 186-193, 2018 | 30 | 2018 |
| Discovery of a celecoxib binding site on prostaglandin E synthase (PTGES) with a cleavable chelation-assisted biotin probe DK Miyamoto, HA Flaxman, HY Wu, J Gao, CM Woo ACS Chemical Biology 14 (12), 2527-2532, 2019 | 27 | 2019 |
| Small Molecule Interactome Mapping by Photo‐Affinity Labeling (SIM‐PAL) to Identify Binding Sites of Small Molecules on a Proteome‐Wide Scale HA Flaxman, DK Miyamoto, CM Woo Current protocols in chemical biology 11 (4), e75, 2019 | 26 | 2019 |
| Enantioselective synthesis and biological evaluation of sanglifehrin A and B and analogs CF Chang, HA Flaxman, CM Woo Angewandte Chemie 133 (31), 17182-17189, 2021 | 15 | 2021 |
| The Cyclimids: Degron-inspired cereblon binders for targeted protein degradation S Ichikawa, NC Payne, W Xu, CF Chang, N Vallavoju, S Frome, ... Cell Chemical Biology, 2024 | 8 | 2024 |
| Sanglifehrin A mitigates multi-organ fibrosis in vivo by inducing secretion of the collagen chaperone cyclophilin B HA Flaxman, MA Chrysovergi, H Han, F Kabir, RT Lister, CF Chang, ... bioRxiv, 2023.03. 09.531890, 2023 | 3 | 2023 |
| E3 ligase binders and uses thereof CM Woo, S Ichikawa, HA Flaxman, W Xu US Patent App. 18/286,740, 2024 | | 2024 |
| Sanglifehrin A mitigates multi-organ fibrosis by targeting the collagen chaperone cyclophilin B HA Flaxman, MA Chrysovergi, H Han, F Kabir, RT Lister, CF Chang, ... JCI Insight, 2024 | | 2024 |
| Structural and mechanistic studies of molecular glues and their targets HA Flaxman Harvard University, 2022 | | 2022 |
| Discovery of a celecoxib binding site on PTGES with a cleavable chelation-assisted biotin probe DK Miyamoto, HA Flaxman, HY Wu, J Gao, CM Woo bioRxiv, 782532, 2019 | | 2019 |
| Structural characterization of protein-small molecule interactions in ternary complexes using photo-affinity labelling and mass spectrometry: Studies with the macrocyclic … H Flaxman, CF Chang, C Woo ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
