Extensive exometabolome analysis reveals extended overflow metabolism in various microorganisms N Paczia, A Nilgen, T Lehmann, J Gätgens, W Wiechert, S Noack Microbial cell factories 11, 1-14, 2012 | 308 | 2012 |
A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level A Grünberger, N Paczia, C Probst, G Schendzielorz, L Eggeling, S Noack, ... Lab on a Chip 12 (11), 2060-2068, 2012 | 134 | 2012 |
Millifluidic culture improves human midbrain organoid vitality and differentiation E Berger, C Magliaro, N Paczia, AS Monzel, P Antony, CL Linster, ... Lab on a Chip 18 (20), 3172-3183, 2018 | 132 | 2018 |
Beyond growth rate 0.6: What drives Corynebacterium glutamicum to higher growth rates in defined medium S Unthan, A Grünberger, J van Ooyen, J Gätgens, J Heinrich, N Paczia, ... Biotechnology and bioengineering 111 (2), 359-371, 2014 | 131 | 2014 |
Failure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency M Veiga-da-Cunha, N Chevalier, X Stephenne, JP Defour, N Paczia, ... Proceedings of the National Academy of Sciences 116 (4), 1241-1250, 2019 | 130 | 2019 |
Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments A Grünberger, J van Ooyen, N Paczia, P Rohe, G Schiendzielorz, ... Biotechnology and bioengineering 110 (1), 220-228, 2013 | 83 | 2013 |
Saccharomyces cerevisiae Forms d-2-Hydroxyglutarate and Couples Its Degradation to d-Lactate Formation via a Cytosolic Transhydrogenase*♦ J Becker-Kettern, N Paczia, JF Conrotte, DP Kay, C Guignard, PP Jung, ... Journal of Biological Chemistry 291 (12), 6036-6058, 2016 | 64 | 2016 |
NAD (P) HX dehydratase (NAXD) deficiency: a novel neurodegenerative disorder exacerbated by febrile illnesses NJ Van Bergen, Y Guo, J Rankin, N Paczia, J Becker-Kettern, LS Kremer, ... Brain 142 (1), 50-58, 2019 | 58 | 2019 |
A versatile active learning workflow for optimization of genetic and metabolic networks A Pandi, C Diehl, A Yazdizadeh Kharrazi, SA Scholz, E Bobkova, L Faure, ... Nature Communications 13 (1), 3876, 2022 | 50 | 2022 |
A synthetic C4 shuttle via the β-hydroxyaspartate cycle in C3 plants MS Roell, L Schada von Borzyskowski, P Westhoff, A Plett, N Paczia, ... Proceedings of the National Academy of Sciences 118 (21), e2022307118, 2021 | 47 | 2021 |
A Modular In Vitro Platform for the Production of Terpenes and Polyketides from CO2 S Sundaram, C Diehl, NS Cortina, J Bamberger, N Paczia, TJ Erb Angewandte Chemie International Edition 60 (30), 16420-16425, 2021 | 41 | 2021 |
Nit1 is a metabolite repair enzyme that hydrolyzes deaminated glutathione A Peracchi, M Veiga-da-Cunha, T Kuhara, KW Ellens, N Paczia, ... Proceedings of the National Academy of Sciences 114 (16), E3233-E3242, 2017 | 40 | 2017 |
Bioelectrocatalytic Cofactor Regeneration Coupled to CO2 Fixation in a Redox‐Active Hydrogel for Stereoselective C−C Bond Formation L Castañeda‐Losada, D Adam, N Paczia, D Buesen, F Steffler, V Sieber, ... Angewandte Chemie International Edition 60 (38), 21056-21061, 2021 | 36 | 2021 |
NAD (P) HX repair deficiency causes central metabolic perturbations in yeast and human cells J Becker‐Kettern, N Paczia, JF Conrotte, C Zhu, O Fiehn, PP Jung, ... The FEBS journal 285 (18), 3376-3401, 2018 | 35 | 2018 |
Engineering a highly efficient carboligase for synthetic one-carbon metabolism M Nattermann, S Burgener, P Pfister, A Chou, L Schulz, SH Lee, N Paczia, ... ACS catalysis 11 (9), 5396-5404, 2021 | 33 | 2021 |
Hydrogen utilization by Methylocystis sp. strain SC2 expands the known metabolic versatility of type IIa methanotrophs A Hakobyan, J Zhu, T Glatter, N Paczia, W Liesack Metabolic Engineering 61, 181-196, 2020 | 33 | 2020 |
Error propagation analysis for quantitative intracellular metabolomics J Tillack, N Paczia, K Nöh, W Wiechert, S Noack Metabolites 2 (4), 1012-1030, 2012 | 32 | 2012 |
Life After Secretion—Yersinia enterocolitica Rapidly Toggles Effector Secretion and Can Resume Cell Division in Response to Changing External Conditions B Milne-Davies, C Helbig, S Wimmi, DWC Cheng, N Paczia, A Diepold Frontiers in microbiology 10, 2128, 2019 | 28 | 2019 |
Natural variation of chronological aging in the Saccharomyces cerevisiae species reveals diet-dependent mechanisms of life span control PP Jung, Z Zhang, N Paczia, C Jaeger, T Ignac, P May, CL Linster npj Aging and Mechanisms of Disease 4 (1), 3, 2018 | 27 | 2018 |
PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing E Danileviciute, N Zeng, CM Capelle, N Paczia, MA Gillespie, ... Nature metabolism 4 (5), 589-607, 2022 | 24 | 2022 |