Advanced chronic kidney disease populations have elevated trimethylamine N-oxide levels associated with increased cardiovascular events RB Kim, BL Morse, O Djurdjev, M Tang, N Muirhead, B Barrett, DT Holmes, ... Kidney international 89 (5), 1144-1152, 2016 | 177 | 2016 |
Diagnosis and management of testosterone deficiency syndrome in men: clinical practice guideline A Morales, RA Bebb, P Manjoo, P Assimakopoulos, J Axler, C Collier, ... Cmaj 187 (18), 1369-1377, 2015 | 148 | 2015 |
Plasma renin activity predicts cardiovascular mortality in the Heart Outcomes Prevention Evaluation (HOPE) study S Verma, M Gupta, DT Holmes, L Xu, H Teoh, S Gupta, S Yusuf, EM Lonn European heart journal 32 (17), 2135-2142, 2011 | 108 | 2011 |
Lipoprotein (a) is an independent risk factor for cardiovascular disease in heterozygous familial hypercholesterolemia DT Holmes, BA Schick, KH Humphries, J Frohlich Clinical chemistry 51 (11), 2067-2073, 2005 | 100 | 2005 |
Reduced magnitude and durability of humoral immune responses to COVID-19 mRNA vaccines among older adults MA Brockman, F Mwimanzi, HR Lapointe, Y Sang, O Agafitei, PK Cheung, ... The Journal of infectious diseases 225 (7), 1129-1140, 2022 | 93 | 2022 |
Laboratory challenges in primary aldosteronism screening and diagnosis M Rehan, JE Raizman, E Cavalier, AC Don-Wauchope, DT Holmes Clinical biochemistry 48 (6), 377-387, 2015 | 88 | 2015 |
Towards the development of an immuno MALDI (iMALDI) mass spectrometry assay for the diagnosis of hypertension JD Reid, DT Holmes, DR Mason, B Shah, CH Borchers Journal of the American Society for Mass Spectrometry 21, 1680-1686, 2010 | 86 | 2010 |
Humoral immune responses to COVID-19 vaccination in people living with HIV receiving suppressive antiretroviral therapy ZL Brumme, F Mwimanzi, HR Lapointe, PK Cheung, Y Sang, MC Duncan, ... npj Vaccines 7 (1), 28, 2022 | 78 | 2022 |
Recurrent hypoglycemia from insulin autoimmune syndrome SL Wong, A Priestman, DT Holmes Journal of general internal medicine 29, 250-254, 2014 | 77 | 2014 |
Cohort profile: Canadian study of prediction of death, dialysis and interim cardiovascular events (CanPREDDICT) A Levin, C Rigatto, B Brendan, F Madore, N Muirhead, D Holmes, ... BMC nephrology 14, 1-11, 2013 | 75 | 2013 |
Concentrations of trace elements and clinical outcomes in hemodialysis patients: a prospective cohort study M Tonelli, N Wiebe, A Bello, CJ Field, JS Gill, BR Hemmelgarn, ... Clinical Journal of the American Society of Nephrology 13 (6), 907-915, 2018 | 74 | 2018 |
Steroid profiling reveals widespread local regulation of glucocorticoid levels during mouse development MD Taves, AW Plumb, BA Sandkam, C Ma, JG Van Der Gugten, ... Endocrinology 156 (2), 511-522, 2015 | 69 | 2015 |
Clinical validation for the aldosterone-to-renin ratio and aldosterone suppression testing using simultaneous fully automated chemiluminescence immunoassays J Manolopoulou, E Fischer, A Dietz, S Diederich, D Holmes, R Junnila, ... Journal of hypertension 33 (12), 2500-2511, 2015 | 66 | 2015 |
The concept of precision extended to the atherogenic index of plasma DT Holmes, J Frohlich, KA Buhr Clinical biochemistry 41 (7-8), 631-635, 2008 | 63 | 2008 |
Biomarkers of inflammation, fibrosis, cardiac stretch and injury predict death but not renal replacement therapy at 1 year in a Canadian chronic kidney disease cohort A Levin, C Rigatto, B Barrett, F Madore, N Muirhead, D Holmes, CM Clase, ... Nephrology Dialysis Transplantation 29 (5), 1037-1047, 2014 | 62 | 2014 |
Determination of serum aldosterone by liquid chromatography and tandem mass spectrometry: a liquid–liquid extraction method for the ABSCIEX API-5000 mass spectrometry system JG Van Der Gugten, J Dubland, HF Liu, A Wang, C Joseph, DT Holmes Journal of clinical pathology 65 (5), 457-462, 2012 | 60 | 2012 |
Asymptomatic hypothyroidism and statin-induced myopathy SL Bar, DT Holmes, J Frohlich Canadian family physician 53 (3), 428-431, 2007 | 58 | 2007 |
Your results may vary: the imprecision of medical measurements JP McCormack, DT Holmes Bmj 368, 2020 | 48 | 2020 |
Clinical translation of MS-based, quantitative plasma proteomics: status, challenges, requirements, and potential AJ Percy, S Byrns, SR Pennington, DT Holmes, NL Anderson, TM Agreste, ... Expert review of proteomics 13 (7), 673-684, 2016 | 47 | 2016 |
Rivaroxaban and apixaban induce clotting factor Xa fibrinolytic activity RLR Carter, K Talbot, WS Hur, SC Meixner, JG Van Der Gugten, ... Journal of Thrombosis and Haemostasis 16 (11), 2276-2288, 2018 | 46 | 2018 |