Adult enteric nervous system in health is maintained by a dynamic balance between neuronal apoptosis and neurogenesis S Kulkarni, MA Micci, J Leser, C Shin, SC Tang, YY Fu, L Liu, Q Li, ... Proceedings of the National Academy of Sciences 114 (18), E3709-E3718, 2017 | 508* | 2017 |
Acute colitis during chronic experimental traumatic brain injury in mice induces dysautonomia and persistent extraintestinal, systemic, and CNS inflammation with exacerbated … M Hanscom, DJ Loane, T Aubretch, J Leser, K Molesworth, N Hedgekar, ... Journal of neuroinflammation 18, 1-31, 2021 | 40 | 2021 |
The cytoskeleton and connected elements in bone cell mechano-transduction NR Gould, OM Torre, JM Leser, JP Stains Bone 149, 115971, 2021 | 35 | 2021 |
Disparate bone anabolic cues activate bone formation by regulating the rapid lysosomal degradation of sclerostin protein NR Gould, KM Williams, HC Joca, OM Torre, JS Lyons, JM Leser, ... Elife 10, e64393, 2021 | 28 | 2021 |
TRPV4 calcium influx controls sclerostin protein loss independent of purinergic calcium oscillations KM Williams, JM Leser, NR Gould, HC Joca, JS Lyons, RJ Khairallah, ... Bone 136, 115356, 2020 | 28 | 2020 |
Homotransfer FRET reporters for live cell imaging NE Snell, VP Rao, KM Seckinger, J Liang, J Leser, AE Mancini, MA Rizzo Biosensors 8 (4), 89, 2018 | 20 | 2018 |
Connexin43 regulates osteoprotegerin expression via ERK1/2-dependent recruitment of Sp1 A Gupta, JM Leser, NR Gould, AM Buo, MC Moorer, JP Stains Biochemical and biophysical research communications 509 (3), 728-733, 2019 | 12 | 2019 |
Aging, osteo-sarcopenia, and musculoskeletal mechano-transduction JM Leser, A Harriot, HV Buck, CW Ward, JP Stains Frontiers in rehabilitation sciences 2, 782848, 2021 | 8 | 2021 |
Age-associated changes in lineage composition of the enteric nervous system regulate gut health and disease S Kulkarni, M Saha, J Slosberg, A Singh, S Nagaraj, L Becker, C Zhang, ... Elife 12, RP88051, 2023 | 7 | 2023 |
In vitro fluid shear stress induced sclerostin degradation and CaMKII activation in osteocytes NR Gould, JM Leser, OM Torre, RJ Khairallah, CW Ward, JP Stains Bio-protocol 11 (23), e4251-e4251, 2021 | 7 | 2021 |
Neural crest-derived neurons are replaced by a newly identified mesodermal lineage in the post-natal and aging enteric nervous system S Kulkarni, M Saha, L Becker, Z Wang, G Liu, J Leser, M Kumar, ... BioRxiv, 1-16, 2020 | 6 | 2020 |
Osteoblast-lineage calcium/calmodulin-dependent kinase 2 delta and gamma regulates bone mass and quality JM Leser, OM Torre, NR Gould, Q Guo, HV Buck, J Kodama, S Otsuru, ... Proceedings of the National Academy of Sciences 120 (47), e2304492120, 2023 | 3 | 2023 |
751 Collagen IV-Pten Signaling Regulates Adult Enteric Neurogenesis In Vitro and In Vivo S Kulkarni, J Leser, M Saha, MA Micci, H Song, PJ Pasricha Gastroenterology 148 (4), S-142, 2015 | 1 | 2015 |
Nitric Oxide Contributes to Rapid Sclerostin Protein Loss Following Mechanical Load HV Buck, OM Torre, JM Leser, NR Gould, CW Ward, JP Stains Biochemical and Biophysical Research Communications, 150315, 2024 | | 2024 |
Deciphering the Role of Microtubule Posttranslational Modifications and Calcium/Calmodulin-Dependent Kinase 2 Delta and Gamma on Osteocyte Function JM Leser University of Maryland, Baltimore, 2023 | | 2023 |
Deciphering the Role of Aging Microtubules on Osteocyte Mechano-Transduction J Leser, R Khairallah, C Ward, J Stains JOURNAL OF BONE AND MINERAL RESEARCH 37, 290-290, 2022 | | 2022 |
Colchicine improves muscle function, enhances bone formation, and reduces white adipose tissue in aged mice but not young mice J Leser, N Gould, G Shi, N Spita, M Mull, R Riddle, C Ward, J Stains JOURNAL OF BONE AND MINERAL RESEARCH 35, 156-156, 2020 | | 2020 |
Microtubule Remodeling Contributes to the Loss of Force and Power in Aging Skeletal Muscle HC Joca, A Harriot, J Leser, A Coleman, G Shi, JP Stains, CW Ward Biophysical Journal 118 (3), 495a, 2020 | | 2020 |
Contribution of Gastrointestinal Microbiota in the Enteric Nervous System of the Small Intestine in Health and Irritable Bowel Syndrome J Leser, S Kulkarni, J Guo, Q Li, PJ Pasricha Gastroenterology 152 (5), S726, 2017 | | 2017 |
135 The Use of Diphtheria Toxin in Transgenic Mice for Regionally Targeted and Cell-Specific Ablation to Recapitulate Putative Models of Motility Disorder J Leser, S Kulkarni, L Liu, D Bigge, N Bessler, M Kumar, A Hasche, ... Gastroenterology 150 (4), S32, 2016 | | 2016 |