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Alia Sagatova
Alia Sagatova
Albert Einstein College of Medicine
在 tcd.ie 的电子邮件经过验证
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引用次数
引用次数
年份
Structural insights into binding of the antifungal drug fluconazole to Saccharomyces cerevisiae lanosterol 14α-demethylase
AA Sagatova, MV Keniya, RK Wilson, BC Monk, JDA Tyndall
Antimicrobial agents and chemotherapy 59 (8), 4982-4989, 2015
1842015
Crystal structures of full-length lanosterol 14α-demethylases of prominent fungal pathogens Candida albicans and Candida glabrata provide tools for antifungal discovery
MV Keniya, M Sabherwal, RK Wilson, MA Woods, AA Sagatova, ...
Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 01134-18, 2018
1162018
Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase
AA Sagatova, MV Keniya, RK Wilson, M Sabherwal, JDA Tyndall, ...
Scientific reports 6 (1), 26213, 2016
1062016
Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design
BC Monk, AA Sagatova, P Hosseini, YN Ruma, RK Wilson, MV Keniya
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1868 (3), 140206, 2020
992020
[Fe2L3]4+ Cylinders Derived from Bis(bidentate) 2-Pyridyl-1,2,3-triazole “Click” Ligands: Synthesis, Structures and Exploration of Biological Activity
SK Vellas, JEM Lewis, M Shankar, A Sagatova, JDA Tyndall, BC Monk, ...
Molecules 18 (6), 6383-6407, 2013
732013
Structural and functional elucidation of yeast lanosterol 14α-demethylase in complex with agrochemical antifungals
JDA Tyndall, M Sabherwal, AA Sagatova, MV Keniya, J Negroni, ...
PLoS One 11 (12), e0167485, 2016
562016
Impact of homologous resistance mutations from pathogenic yeast on Saccharomyces cerevisiae lanosterol 14α-demethylase
AA Sagatova, MV Keniya, JDA Tyndall, BC Monk
Antimicrobial agents and chemotherapy 62 (3), 10.1128/aac. 02242-17, 2018
242018
Strategies to better target fungal squalene monooxygenase
AA Sagatova
Journal of Fungi 7 (1), 49, 2021
182021
Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14alpha-demethylase. Sci Rep 6: 26213
AA Sagatova, MV Keniya, RK Wilson, M Sabherwal, JD Tyndall, BC Monk
72016
The new epoch of structural insights into radical SAM enzymology
J Lachowicz, J Lee, A Sagatova, K Jew, TL Grove
Current Opinion in Structural Biology 83, 102720, 2023
12023
Investigating resistance mutations in the drug target of triazole drugs
A Sagatova
University of Otago, 2016
12016
Strategies to Better Target Fungal Squalene Monooxygenase. J. Fungi 2021, 7, 49
AA Sagatova
s Note: MDPI stays neu-tral with regard to jurisdictional clai-ms in …, 2021
2021
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