Structural insights into binding of the antifungal drug fluconazole to Saccharomyces cerevisiae lanosterol 14α-demethylase AA Sagatova, MV Keniya, RK Wilson, BC Monk, JDA Tyndall Antimicrobial agents and chemotherapy 59 (8), 4982-4989, 2015 | 184 | 2015 |
Crystal structures of full-length lanosterol 14α-demethylases of prominent fungal pathogens Candida albicans and Candida glabrata provide tools for antifungal discovery MV Keniya, M Sabherwal, RK Wilson, MA Woods, AA Sagatova, ... Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 01134-18, 2018 | 116 | 2018 |
Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14α-demethylase AA Sagatova, MV Keniya, RK Wilson, M Sabherwal, JDA Tyndall, ... Scientific reports 6 (1), 26213, 2016 | 106 | 2016 |
Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design BC Monk, AA Sagatova, P Hosseini, YN Ruma, RK Wilson, MV Keniya Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1868 (3), 140206, 2020 | 99 | 2020 |
[Fe2L3]4+ Cylinders Derived from Bis(bidentate) 2-Pyridyl-1,2,3-triazole “Click” Ligands: Synthesis, Structures and Exploration of Biological Activity SK Vellas, JEM Lewis, M Shankar, A Sagatova, JDA Tyndall, BC Monk, ... Molecules 18 (6), 6383-6407, 2013 | 73 | 2013 |
Structural and functional elucidation of yeast lanosterol 14α-demethylase in complex with agrochemical antifungals JDA Tyndall, M Sabherwal, AA Sagatova, MV Keniya, J Negroni, ... PLoS One 11 (12), e0167485, 2016 | 56 | 2016 |
Impact of homologous resistance mutations from pathogenic yeast on Saccharomyces cerevisiae lanosterol 14α-demethylase AA Sagatova, MV Keniya, JDA Tyndall, BC Monk Antimicrobial agents and chemotherapy 62 (3), 10.1128/aac. 02242-17, 2018 | 24 | 2018 |
Strategies to better target fungal squalene monooxygenase AA Sagatova Journal of Fungi 7 (1), 49, 2021 | 18 | 2021 |
Triazole resistance mediated by mutations of a conserved active site tyrosine in fungal lanosterol 14alpha-demethylase. Sci Rep 6: 26213 AA Sagatova, MV Keniya, RK Wilson, M Sabherwal, JD Tyndall, BC Monk | 7 | 2016 |
The new epoch of structural insights into radical SAM enzymology J Lachowicz, J Lee, A Sagatova, K Jew, TL Grove Current Opinion in Structural Biology 83, 102720, 2023 | 1 | 2023 |
Investigating resistance mutations in the drug target of triazole drugs A Sagatova University of Otago, 2016 | 1 | 2016 |
Strategies to Better Target Fungal Squalene Monooxygenase. J. Fungi 2021, 7, 49 AA Sagatova s Note: MDPI stays neu-tral with regard to jurisdictional clai-ms in …, 2021 | | 2021 |