ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF TG Boulton, SH Nye, DJ Robbins, NY Ip, E Radzlejewska, ... Cell 65 (4), 663-675, 1991 | 2533 | 1991 |
Atomic structure of the MAP kinase ERK2 at 2.3 Å resolution F Zhang, A Strand, D Robbins, MH Cobb, EJ Goldsmith Nature 367 (6465), 704-711, 1994 | 783 | 1994 |
The interaction of SV40 small tumor antigen with protein phosphatase 2A stimulates the map kinase pathway and induces cell proliferation E Sontag, S Fedorov, C Kamibayashi, D Robbins, M Cobb, M Mumby Cell 75 (5), 887-897, 1993 | 680 | 1993 |
Extracellular signal-regulated kinases: ERKs in progress. MH Cobb, TG Boulton, DJ Robbins Cell regulation 2 (12), 965-978, 1991 | 661 | 1991 |
Regulation and properties of extracellular signal-regulated protein kinases 1 and 2 in vitro. DJ Robbins, E Zhen, H Owaki, CA Vanderbilt, D Ebert, TD Geppert, ... Journal of Biological Chemistry 268 (7), 5097-5106, 1993 | 613 | 1993 |
A freely diffusible form of Sonic hedgehog mediates long-range signalling X Zeng, JA Goetz, LM Suber, WJ Scott, CM Schreiner, DJ Robbins Nature 411 (6838), 716-720, 2001 | 558 | 2001 |
The Hedgehog signal transduction network DJ Robbins, DL Fei, NA Riobo Science signaling 5 (246), re6-re6, 2012 | 483 | 2012 |
Hedgehog elicits signal transduction by means of a large complex containing the kinesin-related protein costal2 DJ Robbins, KE Nybakken, R Kobayashi, JC Sisson, JM Bishop, ... Cell 90 (2), 225-234, 1997 | 455 | 1997 |
Evidence for a Ras-dependent extracellular signal-regulated protein kinase (ERK) cascade DJ Robbins, M Cheng, E Zhen, CA Vanderbilt, LA Feig, MH Cobb Proceedings of the National Academy of Sciences 89 (15), 6924-6928, 1992 | 256 | 1992 |
G protein Gα i functions immediately downstream of Smoothened in Hedgehog signalling SK Ogden, DL Fei, NS Schilling, YF Ahmed, J Hwa, DJ Robbins Nature 456 (7224), 967-970, 2008 | 250 | 2008 |
TGFβ2 mediates the effects of Hedgehog on hypertrophic differentiation and PTHrP expression J Alvarez, P Sohn, X Zeng, T Doetschman, DJ Robbins, R Serra Development 129 (8), 1913-1924, 2002 | 218 | 2002 |
Frequent requirement of hedgehog signaling in non-small cell lung carcinoma Z Yuan, JA Goetz, S Singh, SK Ogden, WJ Petty, CC Black, VA Memoli, ... Oncogene 26 (7), 1046-1055, 2007 | 214 | 2007 |
MEKK1 phosphorylates MEK1 and MEK2 but does not cause activation of mitogen-activated protein kinase S Xu, D Robbins, J Frost, A Dang, C Lange-Carter, MH Cobb Proceedings of the National Academy of Sciences 92 (15), 6808-6812, 1995 | 213 | 1995 |
Shk1, a homolog of the Saccharomyces cerevisiae Ste20 and mammalian p65PAK protein kinases, is a component of a Ras/Cdc42 signaling module in the fission yeast … S Marcus, A Polverino, E Chang, D Robbins, MH Cobb, MH Wigler Proceedings of the National Academy of Sciences 92 (13), 6180-6184, 1995 | 208 | 1995 |
The mitogen-activated protein kinases, ERK1 and ERK2. MH Cobb, JE Hepler, M Cheng, D Robbins Seminars in cancer biology 5 (4), 261-268, 1994 | 193 | 1994 |
Characterization of a high-molecular-weight Notch complex in the nucleus of Notchic-transformed RKE cells and in a human T-cell leukemia cell line S Jeffries, DJ Robbins, AJ Capobianco Molecular and cellular biology 22 (11), 3927-3941, 2002 | 190 | 2002 |
Cloning of rat MEK kinase 1 cDNA reveals an endogenous membrane-associated 195-kDa protein with a large regulatory domain S Xu, DJ Robbins, LB Christerson, JM English, CA Vanderbilt, MH Cobb Proceedings of the National Academy of Sciences 93 (11), 5291-5295, 1996 | 180 | 1996 |
ERKs, extracellular signal-regulated MAP-2 kinases MH Cobb, DJ Robbins, TG Boulton Current opinion in cell biology 3 (6), 1025-1032, 1991 | 179 | 1991 |
A highly conserved amino-terminal region of sonic hedgehog is required for the formation of its freely diffusible multimeric form JA Goetz, S Singh, LM Suber, FJ Kull, DJ Robbins Journal of Biological Chemistry 281 (7), 4087-4093, 2006 | 164 | 2006 |
Regulation of Hedgehog signaling: a complex story SK Ogden, M Ascano Jr, MA Stegman, DJ Robbins Biochemical pharmacology 67 (5), 805-814, 2004 | 149 | 2004 |