| CNVkit: genome-wide copy number detection and visualization from targeted DNA sequencing E Talevich, AH Shain, T Botton, BC Bastian PLoS computational biology 12 (4), e1004873, 2016 | 1571 | 2016 |
| Kinase fusions are frequent in Spitz tumours and spitzoid melanomas T Wiesner, J He, R Yelensky, R Esteve-Puig, T Botton, I Yeh, D Lipson, ... Nature communications 5 (1), 3116, 2014 | 612 | 2014 |
| Metformin inhibits melanoma development through autophagy and apoptosis mechanisms T Tomic, T Botton, M Cerezo, G Robert, F Luciano, A Puissant, P Gounon, ... Cell death & disease 2 (9), e199-e199, 2011 | 345 | 2011 |
| Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway AH Shain, M Garrido, T Botton, E Talevich, I Yeh, JZ Sanborn, J Chung, ... Nature genetics 47 (10), 1194-1199, 2015 | 261 | 2015 |
| Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny Y Cheli, S Guiliano, T Botton, S Rocchi, V Hofman, P Hofman, ... Oncogene 30 (20), 2307-2318, 2011 | 252 | 2011 |
| Activating MET kinase rearrangements in melanoma and Spitz tumours I Yeh, T Botton, E Talevich, AH Shain, AJ Sparatta, A De La Fouchardiere, ... Nature communications 6 (1), 7174, 2015 | 247 | 2015 |
| Compounds triggering ER stress exert anti-melanoma effects and overcome BRAF inhibitor resistance M Cerezo, A Lehraiki, A Millet, F Rouaud, M Plaisant, E Jaune, T Botton, ... Cancer cell 29 (6), 805-819, 2016 | 244 | 2016 |
| NTRK3 kinase fusions in Spitz tumours I Yeh, MK Tee, T Botton, AH Shain, AJ Sparatta, A Gagnon, SS Vemula, ... The Journal of pathology 240 (3), 282-290, 2016 | 149 | 2016 |
| Bi-allelic loss of CDKN2A initiates melanoma invasion via BRN2 activation H Zeng, A Jorapur, AH Shain, UE Lang, R Torres, Y Zhang, AS McNeal, ... Cancer cell 34 (1), 56-68. e9, 2018 | 129 | 2018 |
| Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy T Botton, I Yeh, T Nelson, SS Vemula, A Sparatta, MC Garrido, M Allegra, ... Pigment cell & melanoma research 26 (6), 845-851, 2013 | 129 | 2013 |
| Genetic heterogeneity of BRAF fusion kinases in melanoma affects drug responses T Botton, E Talevich, VK Mishra, T Zhang, AH Shain, C Berquet, ... Cell reports 29 (3), 573-588. e7, 2019 | 76 | 2019 |
| Clinical activity of the MEK inhibitor trametinib in metastatic melanoma containing BRAF kinase fusion AM Menzies, I Yeh, T Botton, BC Bastian, RA Scolyer, GV Long Pigment cell & melanoma research 28 (5), 607, 2015 | 76 | 2015 |
| In vitro and in vivo anti-melanoma effects of ciglitazone T Botton, A Puissant, P Bahadoran, JS Annicotte, L Fajas, JP Ortonne, ... Journal of Investigative Dermatology 129 (5), 1208-1218, 2009 | 72 | 2009 |
| Ciglitazone negatively regulates CXCL1 signaling through MITF to suppress melanoma growth T Botton, A Puissant, Y Cheli, T Tomic, S Giuliano, L Fajas, M Deckert, ... Cell Death & Differentiation 18 (1), 109-121, 2011 | 44 | 2011 |
| CNVkit: Copy number detection and visualization for targeted sequencing using off-target reads E Talevich, AH Shain, T Botton, BC Bastian BioRxiv, 010876, 2014 | 24 | 2014 |
| Discovery of a new molecule inducing melanoma cell death: dual AMPK/MELK targeting for novel melanoma therapies E Jaune, E Cavazza, C Ronco, O Grytsai, P Abbe, N Tekaya, M Zerhouni, ... Cell Death & Disease 12 (1), 64, 2021 | 19 | 2021 |
| Rac1 dynamics in the human opportunistic fungal pathogen Candida albicans R Vauchelles, D Stalder, T Botton, RA Arkowitz, M Bassilana PLoS One 5 (10), e15400, 2010 | 17 | 2010 |
| Melanoma BRAF fusions T Botton, I Yeh, BC Bastian Clinical Cancer Research 20 (24), 6631-6631, 2014 | 6 | 2014 |
| Hybrid Capture‐Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1‐Mutant Cholangiocarcinoma Harboring a … HC Lim, M Montesion, T Botton, EA Collisson, SE Umetsu, SC Behr, ... The Oncologist 23 (9), 998-1003, 2018 | 2 | 2018 |
| Dual targeting of GPX4 and TXNRD1 triggers eradication of AML cells through induction of apoptosis and ferroptosis C Favreau, C Savy, M Bourgoin, T Botton, S Bailly, F Granger, C Birck, ... bioRxiv, 2024.04. 03.584800, 2024 | 1 | 2024 |
