Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice F Meng, K Wang, T Aoyama, SI Grivennikov, YH Paik, D Scholten, ... Gastroenterology 143 (3), 765-776. e3, 2012 | 718 | 2012 |
Origin of myofibroblasts in the fibrotic liver in mice K Iwaisako, C Jiang, M Zhang, M Cong, TJ Moore-Morris, TJ Park, X Liu, ... Proceedings of the National Academy of Sciences 111 (32), E3297-E3305, 2014 | 549 | 2014 |
Fructose stimulated de novo lipogenesis is promoted by inflammation J Todoric, G Di Caro, S Reibe, DC Henstridge, CR Green, A Vrbanac, ... Nature metabolism 2 (10), 1034-1045, 2020 | 229 | 2020 |
The types of hepatic myofibroblasts contributing to liver fibrosis of different etiologies J Xu, X Liu, Y Koyama, P Wang, T Lan, IG Kim, IH Kim, HY Ma, ... Frontiers in pharmacology 5, 167, 2014 | 152 | 2014 |
Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis MF Bustamante, PG Oliveira, R Garcia-Carbonell, AP Croft, JM Smith, ... Annals of the rheumatic diseases 77 (11), 1636-1643, 2018 | 143 | 2018 |
IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease HY Ma, G Yamamoto, J Xu, X Liu, D Karin, JY Kim, LB Alexandrov, ... Journal of hepatology 72 (5), 946-959, 2020 | 140 | 2020 |
Identification of lineage-specific transcription factors that prevent activation of hepatic stellate cells and promote fibrosis resolution X Liu, J Xu, S Rosenthal, L Zhang, R McCubbin, N Meshgin, L Shang, ... Gastroenterology 158 (6), 1728-1744. e14, 2020 | 139 | 2020 |
New developments on the treatment of liver fibrosis Y Koyama, J Xu, X Liu, DA Brenner Digestive diseases 34 (5), 589-596, 2016 | 132 | 2016 |
Human hepatic stellate cell isolation and characterization L Shang, M Hosseini, X Liu, T Kisseleva, DA Brenner Journal of gastroenterology 53, 6-17, 2018 | 118 | 2018 |
Reversibility of liver fibrosis and inactivation of fibrogenic myofibroblasts X Liu, J Xu, DA Brenner, T Kisseleva Current pathobiology reports 1, 209-214, 2013 | 116 | 2013 |
Activated hepatic stellate cells and portal fibroblasts contribute to cholestatic liver fibrosis in MDR2 knockout mice T Nishio, R Hu, Y Koyama, S Liang, SB Rosenthal, G Yamamoto, D Karin, ... Journal of Hepatology 71 (3), 573-585, 2019 | 106 | 2019 |
Promising therapy candidates for liver fibrosis P Wang, Y Koyama, X Liu, J Xu, HY Ma, S Liang, IH Kim, DA Brenner, ... Frontiers in physiology 7, 164585, 2016 | 92 | 2016 |
Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis Y Koyama, P Wang, S Liang, K Iwaisako, X Liu, J Xu, M Zhang, M Sun, ... The Journal of clinical investigation 127 (4), 1254-1270, 2017 | 89 | 2017 |
NADPH oxidase 1 in liver macrophages promotes inflammation and tumor development in mice S Liang, HY Ma, Z Zhong, D Dhar, X Liu, J Xu, Y Koyama, T Nishio, ... Gastroenterology 156 (4), 1156-1172. e6, 2019 | 85 | 2019 |
Heterogeneity of HSC s in a Mouse Model of NASH SB Rosenthal, X Liu, S Ganguly, D Dhar, MP Pasillas, E Ricciardelli, RZ Li, ... Hepatology 74 (2), 667-685, 2021 | 81 | 2021 |
Aging increases the susceptibility of hepatic inflammation, liver fibrosis and aging in response to high-fat diet in mice IH Kim, J Xu, X Liu, Y Koyama, HY Ma, K Diggle, YH You, JM Schilling, ... Age 38, 291-302, 2016 | 75 | 2016 |
Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis H Gao, Z Jin, G Bandyopadhyay, G Wang, D Zhang, KC e Rocha, X Liu, ... Cell metabolism 34 (8), 1201-1213. e5, 2022 | 71 | 2022 |
An autocrine signaling circuit in hepatic stellate cells underlies advanced fibrosis in nonalcoholic steatohepatitis S Wang, K Li, E Pickholz, R Dobie, KP Matchett, NC Henderson, ... Science translational medicine 15 (677), eadd3949, 2023 | 66 | 2023 |
Coordinated regulation of transcription factor Bcl11b activity in thymocytes by the mitogen-activated protein kinase (MAPK) pathways and protein sumoylation L Zhang, WK Vogel, X Liu, A Topark-Ngarm, BL Arbogast, CS Maier, ... Journal of Biological Chemistry 287 (32), 26971-26988, 2012 | 66 | 2012 |
MiR-690 treatment causes decreased fibrosis and steatosis and restores specific Kupffer cell functions in NASH H Gao, Z Jin, G Bandyopadhyay, KC e Rocha, X Liu, H Zhao, D Zhang, ... Cell metabolism 34 (7), 978-990. e4, 2022 | 54 | 2022 |