TRIM32 protein modulates type I interferon induction and cellular antiviral response by targeting MITA/STING protein for K63-linked ubiquitination J Zhang, MM Hu, YY Wang, HB Shu Journal of Biological Chemistry 287 (34), 28646-28655, 2012 | 379 | 2012 |
Sumoylation promotes the stability of the DNA sensor cGAS and the adaptor STING to regulate the kinetics of response to DNA virus MM Hu, Q Yang, XQ Xie, CY Liao, H Lin, TT Liu, L Yin, HB Shu Immunity 45 (3), 555-569, 2016 | 305 | 2016 |
RNF26 temporally regulates virus-triggered type I interferon induction by two distinct mechanisms Y Qin, MT Zhou, MM Hu, YH Hu, J Zhang, L Guo, B Zhong, HB Shu PLoS pathogens 10 (9), e1004358, 2014 | 196 | 2014 |
Human cytomegalovirus tegument protein UL82 inhibits STING-mediated signaling to evade antiviral immunity YZ Fu, S Su, YQ Gao, PP Wang, ZF Huang, MM Hu, WW Luo, S Li, ... Cell host & microbe 21 (2), 231-243, 2017 | 193 | 2017 |
TRIM4 modulates type I interferon induction and cellular antiviral response by targeting RIG-I for K63-linked ubiquitination J Yan, Q Li, AP Mao, MM Hu, HB Shu Journal of molecular cell biology 6 (2), 154-163, 2014 | 187 | 2014 |
TRIM38 inhibits TNFα-and IL-1β–triggered NF-κB activation by mediating lysosome-dependent degradation of TAB2/3 MM Hu, Q Yang, J Zhang, SM Liu, Y Zhang, H Lin, ZF Huang, YY Wang, ... Proceedings of the National Academy of Sciences 111 (4), 1509-1514, 2014 | 131 | 2014 |
Innate immunity to RNA virus is regulated by temporal and reversible sumoylation of RIG-I and MDA5 MM Hu, CY Liao, Q Yang, XQ Xie, HB Shu Journal of Experimental Medicine 214 (4), 973-989, 2017 | 121 | 2017 |
The zinc-finger protein ZCCHC3 binds RNA and facilitates viral RNA sensing and activation of the RIG-I-like receptors H Lian, R Zang, J Wei, W Ye, MM Hu, YD Chen, XN Zhang, Y Guo, CQ Lei, ... Immunity 49 (3), 438-448. e5, 2018 | 111 | 2018 |
ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response H Lian, J Wei, R Zang, W Ye, Q Yang, XN Zhang, YD Chen, YZ Fu, MM Hu, ... Nature communications 9 (1), 3349, 2018 | 111 | 2018 |
TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses Q Yang, TT Liu, H Lin, M Zhang, J Wei, WW Luo, YH Hu, B Zhong, MM Hu, ... PLoS pathogens 13 (9), e1006600, 2017 | 108 | 2017 |
Innate immune response to cytoplasmic DNA: mechanisms and diseases MM Hu, HB Shu Annual review of immunology 38 (1), 79-98, 2020 | 101 | 2020 |
Phosphorylation of cGAS by CDK1 impairs self-DNA sensing in mitosis L Zhong, MM Hu, LJ Bian, Y Liu, Q Chen, HB Shu Cell discovery 6 (1), 26, 2020 | 98 | 2020 |
Virus-induced accumulation of intracellular bile acids activates the TGR5-β-arrestin-SRC axis to enable innate antiviral immunity MM Hu, WR He, P Gao, Q Yang, K He, LB Cao, S Li, YQ Feng, HB Shu Cell research 29 (3), 193-205, 2019 | 86 | 2019 |
Cytoplasmic mechanisms of recognition and defense of microbial nucleic acids MM Hu, HB Shu Annual review of cell and developmental biology 34 (1), 357-379, 2018 | 86 | 2018 |
TRIM38 negatively regulates TLR3/4-mediated innate immune and inflammatory responses by two sequential and distinct mechanisms MM Hu, XQ Xie, Q Yang, CY Liao, W Ye, H Lin, HB Shu The Journal of Immunology 195 (9), 4415-4425, 2015 | 84 | 2015 |
TRIM8 negatively regulates TLR3/4-mediated innate immune response by blocking TRIF–TBK1 interaction W Ye, MM Hu, CQ Lei, Q Zhou, H Lin, MS Sun, HB Shu The Journal of Immunology 199 (5), 1856-1864, 2017 | 73 | 2017 |
Multifaceted roles of TRIM38 in innate immune and inflammatory responses MM Hu, HB Shu Cellular & molecular immunology 14 (4), 331-338, 2017 | 71 | 2017 |
KAT5 acetylates cGAS to promote innate immune response to DNA virus ZM Song, H Lin, XM Yi, W Guo, MM Hu, HB Shu Proceedings of the National Academy of Sciences 117 (35), 21568-21575, 2020 | 70 | 2020 |
MARCH3 attenuates IL-1β–triggered inflammation by mediating K48-linked polyubiquitination and degradation of IL-1RI H Lin, D Gao, MM Hu, M Zhang, XX Wu, L Feng, WH Xu, Q Yang, X Zhong, ... Proceedings of the National Academy of Sciences 115 (49), 12483-12488, 2018 | 37 | 2018 |
SNX8 modulates innate immune response to DNA virus by mediating trafficking and activation of MITA J Wei, H Lian, W Guo, YD Chen, XN Zhang, R Zang, L Zhong, Q Yang, ... PLoS Pathogens 14 (10), e1007336, 2018 | 37 | 2018 |