| Selectivity determinants of GPCR–G-protein binding T Flock, AS Hauser, N Lund, DE Gloriam, S Balaji, MM Babu Nature 545 (7654), 317-322, 2017 | 378 | 2017 |
| Universal allosteric mechanism for Gα activation by GPCRs T Flock, CNJ Ravarani, D Sun, AJ Venkatakrishnan, M Kayikci, CG Tate, ... Nature 524 (7564), 173-179, 2015 | 374 | 2015 |
| Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region AJ Venkatakrishnan, X Deupi, G Lebon, FM Heydenreich, T Flock, ... Nature 536 (7617), 484-487, 2016 | 321 | 2016 |
| Controlling entropy to tune the functions of intrinsically disordered regions T Flock, RJ Weatheritt, NS Latysheva, MM Babu Current opinion in structural biology 26, 62-72, 2014 | 156 | 2014 |
| An online resource for GPCR structure determination and analysis C Munk, E Mutt, V Isberg, LF Nikolajsen, JM Bibbe, T Flock, MA Hanson, ... Nature methods 16 (2), 151-162, 2019 | 128 | 2019 |
| General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH S Brinkmann-Chen, T Flock, JKB Cahn, CD Snow, EM Brustad, ... Proceedings of the National Academy of Sciences 110 (27), 10946-10951, 2013 | 126 | 2013 |
| Visualization and analysis of non-covalent contacts using the Protein Contacts Atlas M Kayikci, AJ Venkatakrishnan, J Scott-Brown, CNJ Ravarani, T Flock, ... Nature structural & molecular biology 25 (2), 185-194, 2018 | 113 | 2018 |
| Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation D Mayer, FF Damberger, M Samarasimhareddy, M Feldmueller, ... Nature communications 10 (1), 1261, 2019 | 110 | 2019 |
| Molecular mechanism of modulating arrestin conformation by GPCR phosphorylation A Sente, R Peer, A Srivastava, M Baidya, AM Lesk, S Balaji, AK Shukla, ... Nature structural & molecular biology 25 (6), 538-545, 2018 | 108 | 2018 |
| Structured and disordered facets of the GPCR fold AJ Venkatakrishnan, T Flock, DE Prado, ME Oates, J Gough, MM Babu Current Opinion in Structural Biology 27, 129-137, 2014 | 85 | 2014 |
| Crystal structure of rhodopsin in complex with a mini-Go sheds light on the principles of G protein selectivity CJ Tsai, F Pamula, R Nehmé, J Mühle, T Weinert, T Flock, P Nogly, ... Science advances 4 (9), eaat7052, 2018 | 79 | 2018 |
| Probing Gαi1 protein activation at single–amino acid resolution D Sun, T Flock, X Deupi, S Maeda, M Matkovic, S Mendieta, D Mayer, ... Nature structural & molecular biology 22 (9), 686-694, 2015 | 76 | 2015 |
| Molecular principles of gene fusion mediated rewiring of protein interaction networks in cancer NS Latysheva, ME Oates, L Maddox, T Flock, J Gough, M Buljan, ... Molecular cell 63 (4), 579-592, 2016 | 63 | 2016 |
| Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit CJ Tsai, J Marino, R Adaixo, F Pamula, J Muehle, S Maeda, T Flock, ... Elife 8, e46041, 2019 | 57 | 2019 |
| How do disordered regions achieve comparable functions to structured domains? NS Latysheva, T Flock, RJ Weatheritt, S Chavali, MM Babu Protein Science 24 (6), 909-922, 2015 | 54 | 2015 |
| Exploiting sequence and stability information for directing nanobody stability engineering P Kunz, T Flock, N Soler, M Zaiss, C Vincke, Y Sterckx, D Kastelic, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1861 (9), 2196-2205, 2017 | 53 | 2017 |
| Cotranslational protein assembly imposes evolutionary constraints on homomeric proteins E Natan, T Endoh, L Haim-Vilmovsky, T Flock, G Chalancon, JTS Hopper, ... Nature structural & molecular biology 25 (3), 279-288, 2018 | 42 | 2018 |
| Convergent evolution of tertiary structure in rhodopsin visual proteins from vertebrates and box jellyfish E Gerrard, E Mutt, T Nagata, M Koyanagi, T Flock, E Lesca, GFX Schertler, ... Proceedings of the National Academy of Sciences 115 (24), 6201-6206, 2018 | 23 | 2018 |
| Molecular determinants underlying functional innovations of TBP and their impact on transcription initiation CNJ Ravarani, T Flock, S Chavali, M Anandapadamanaban, MM Babu, ... Nature Communications 11 (1), 2384, 2020 | 22 | 2020 |
| Deciphering membrane protein structures from protein sequences T Flock, AJ Venkatakrishnan, KR Vinothkumar, MM Babu Genome biology 13, 1-4, 2012 | 8 | 2012 |
