Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal D Sun, M Luo, M Jeong, B Rodriguez, Z Xia, R Hannah, H Wang, T Le, ... Cell Stem Cell 14 (5), 673-688, 2014 | 633 | 2014 |
The polygenic and monogenic basis of blood traits and diseases D Vuckovic, EL Bao, P Akbari, CA Lareau, A Mousas, T Jiang, MH Chen, ... MedRxiv, 2020 | 461 | 2020 |
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype K Gabrusiewicz, B Rodriguez, J Wei, Y Hashimoto, LM Healy, SN Maiti, ... JCI Insight 1 (2), 2016 | 431 | 2016 |
Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations MH Chen, LM Raffield, A Mousas, S Sakaue, JE Huffman, A Moscati, ... Cell 182 (5), 1198-1213. e14, 2020 | 426 | 2020 |
Dnmt3a and dnmt3b have overlapping and distinct functions in hematopoietic stem cells GA Challen, D Sun, A Mayle, M Jeong, M Luo, B Rodriguez, C Mallaney, ... Cell stem cell 15 (3), 350-364, 2014 | 372 | 2014 |
Broad H3K4me3 is associated with increased transcription elongation and enhancer activity at tumor-suppressor genes K Chen, Z Chen, D Wu, L Zhang, X Lin, J Su, B Rodriguez, Y Xi, Z Xia, ... Nature Genetics, 2015 | 327 | 2015 |
Large conserved domains of low DNA methylation maintained by Dnmt3a M Jeong, D Sun, M Luo, Y Huang, GA Challen, B Rodriguez, X Zhang, ... Nature genetics 46 (1), 17-23, 2014 | 320 | 2014 |
MOABS: model based analysis of bisulfite sequencing data D Sun, Y Xi, B Rodriguez, HJ Park, P Tong, M Meong, MA Goodell, W Li Genome Biol 15 (2), R38, 2014 | 289 | 2014 |
Dnmt3a loss predisposes murine hematopoietic stem cells to malignant transformation A Mayle, L Yang, B Rodriguez, T Zhou, E Chang, CV Curry, GA Challen, ... Blood 125 (4), 629-638, 2015 | 279 | 2015 |
Loss of Dnmt3a immortalizes hematopoietic stem cells in vivo M Jeong, HJ Park, H Celik, EL Ostrander, JM Reyes, A Guzman, ... Cell reports 23 (1), 1, 2018 | 203 | 2018 |
Long Non-Coding RNAs Control Hematopoietic Stem Cell Function M Luo, M Jeong, D Sun, HJ Park, BAT Rodriguez, Z Xia, L Yang, X Zhang, ... Cell stem cell 16 (4), 426-438, 2015 | 179 | 2015 |
DNMT3A loss drives enhancer hypomethylation in FLT3-ITD-associated leukemias L Yang, B Rodriguez, A Mayle, HJ Park, X Lin, M Luo, M Jeong, CV Curry, ... Elsevier (Cell Press), 2016 | 161 | 2016 |
Epithelial progeny of estrogen-exposed breast progenitor cells display a cancer-like methylome ASL Cheng, AC Culhane, MWY Chan, CR Venkataramu, M Ehrich, ... Cancer research 68 (6), 1786-1796, 2008 | 158 | 2008 |
Epigenetic influences of low-dose bisphenol A in primary human breast epithelial cells YI Weng, PY Hsu, S Liyanarachchi, J Liu, DE Deatherage, YW Huang, ... Toxicology and applied pharmacology 248 (2), 111-121, 2010 | 157 | 2010 |
Xenoestrogen-induced epigenetic repression of microRNA-9-3 in breast epithelial cells PY Hsu, DE Deatherage, BAT Rodriguez, S Liyanarachchi, YI Weng, ... Cancer research 69 (14), 5936-5945, 2009 | 156 | 2009 |
3′ UTR shortening represses tumor-suppressor genes in trans by disrupting ceRNA crosstalk HJ Park, P Ji, S Kim, Z Xia, B Rodriguez, L Li, J Su, K Chen, CP Masamha, ... Nature genetics, 1, 2018 | 147 | 2018 |
DOT1L as a therapeutic target for the treatment of DNMT3A-mutant acute myeloid leukemia RE Rau, BA Rodriguez, M Luo, M Jeong, A Rosen, JH Rogers, ... Blood 128 (7), 971-981, 2016 | 130 | 2016 |
Short-read, high-throughput sequencing technology for STR genotyping DM Bornman, ME Hester, JM Schuetter, MD Kasoji, A Minard-Smith, ... BioTechniques. Rapid dispatches 2012, 1, 2012 | 129 | 2012 |
Estrogen-mediated epigenetic repression of large chromosomal regions through DNA looping PY Hsu, HK Hsu, GAC Singer, PS Yan, BAT Rodriguez, JC Liu, YI Weng, ... Genome research 20 (6), 733-744, 2010 | 114 | 2010 |
Genome-wide methylation profiling in decitabine-treated patients with acute myeloid leukemia P Yan, D Frankhouser, M Murphy, HH Tam, B Rodriguez, J Curfman, ... Blood 120 (12), 2466-2474, 2012 | 106 | 2012 |