Identification, characterization, and inhibition of Plasmodium falciparum β-hydroxyacyl-acyl carrier protein dehydratase (FabZ) SK Sharma, M Kapoor, TNC Ramya, S Kumar, G Kumar, R Modak, ... Journal of Biological Chemistry 278 (46), 45661, 2003 | 130 | 2003 |
Discovery of a rhodanine class of compounds as inhibitors of Plasmodium falciparum enoyl-acyl carrier protein reductase G Kumar, P Parasuraman, SK Sharma, T Banerjee, K Karmodiya, ... Journal of medicinal chemistry 50 (11), 2665-2675, 2007 | 119 | 2007 |
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Anti-Tumor Efficacy. S Banerjee, KE Arnst, Y Wang, G Kumar, S Deng, L Yang, GB Li, J Yang, ... Journal of Medicinal Chemistry 61, 1704-1718, 2018 | 103 | 2018 |
Novel diphenyl ethers: design, docking studies, synthesis and inhibition of enoyl ACP reductase of Plasmodium falciparum and Escherichia coli M Chhibber, G Kumar, P Parasuraman, TNC Ramya, N Surolia, A Surolia Bioorganic & medicinal chemistry 14 (23), 8086-8098, 2006 | 91 | 2006 |
The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations in Staphylococcus aureus Dihydropteroate Synthase E Griffith, M Wallace, Y Wu, G Kumar, S Gajewski, P Jackson, Z Zheng, ... Front. Microbiol. - Antimicrobials, Resistance and Chemotherapy 9, 2018 | 76 | 2018 |
Structure-Guided Design, Synthesis, and Biological Evaluation of (2-(1H-Indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethoxyphenyl) Methanone (ABI-231) Analogues Targeting the … Q Wang, K Arnst, Y Wang, G Kumar, D Ma, SW White, DD Miller, W Li, ... Journal of Medicinal Chemistry, 2019 | 73 | 2019 |
Stable Analogues of OSB‐AMP: Potent Inhibitors of MenE, the o‐Succinylbenzoate‐CoA Synthetase from Bacterial Menaquinone Biosynthesis X Lu, R Zhou, I Sharma, X Li, G Kumar, S Swaminathan, PJ Tonge, ... ChemBioChem 13 (1), 129-136, 2012 | 72 | 2012 |
Green tea catechins potentiate triclosan binding to enoyl-ACP reductase from Plasmodium falciparum (PfENR) SK Sharma, P Parasuraman, G Kumar, N Surolia, A Surolia Journal of medicinal chemistry 50 (4), 765-775, 2007 | 71 | 2007 |
Identification of the I38T PA Substitution as a Resistance Marker for Next-Generation Influenza Virus Endonuclease Inhibitors J Jones, G Kumar, S Barman, I Najera, S White, R Webby, E Govorkova MBio 9 (2), doi:10.1128/mBio.00430-18, 2018 | 67 | 2018 |
NMR and molecular modelling studies on the interaction of fluconazole with β-cyclodextrin SK Upadhyay, G Kumar Chemistry Central Journal 3, 1-9, 2009 | 67 | 2009 |
A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer R Robertson, J Yao, S Gajewski, G Kumar, E Martin, C Rock, S White Nature Structural & Molecular Biology 24, 666-671, 2017 | 65 | 2017 |
Unfolding studies on soybean agglutinin and concanavalin a tetramers: a comparative account S Sinha, N Mitra, G Kumar, K Bajaj, A Surolia Biophysical journal 88 (2), 1300-1310, 2005 | 63 | 2005 |
N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes M Carcelli, D Rogolino, A Gatti, L De Luca, M Sechi, G Kumar, S White, ... Scientific Reports 6 (31500), 1-14, 2016 | 59 | 2016 |
Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor MS Song, G Kumar, WR Shadrick, W Zhou, T Jeevan, Z Li, PJ Slavish, ... Proceedings of the National Academy of Sciences 113 (13), 3669-3674, 2016 | 57 | 2016 |
Functional characterization of β-ketoacyl-ACP reductase (FabG) from Plasmodium falciparum S Pillai, C Rajagopal, M Kapoor, G Kumar, A Gupta, N Surolia Biochemical and biophysical research communications 303 (1), 387-392, 2003 | 50 | 2003 |
Structural modification of the 3, 4, 5-trimethoxyphenyl moiety in the tubulin inhibitor VERU-111 leads to improved antiproliferative activities Q Wang, KE Arnst, Y Wang, G Kumar, D Ma, H Chen, Z Wu, J Yang, ... Journal of medicinal chemistry 61 (17), 7877-7891, 2018 | 47 | 2018 |
Unique determinants of neuraminidase inhibitor resistance among N3, N7, and N9 avian influenza viruses MS Song, BM Marathe, G Kumar, SS Wong, A Rubrum, M Zanin, YK Choi, ... Journal of virology 89 (21), 10891-10900, 2015 | 45 | 2015 |
Recent Advances in Computer-Aided Drug Design as Applied to Anti-Influenza Drug Discovery PL Mallipeddi, G Kumar, SW White, TR Webb Current Topics in Medicinal Chemistry 14 (16), 1875-1889, 2014 | 43 | 2014 |
Structure–Activity Relationship Study of Novel 6-Aryl-2-benzoyl-pyridines as Tubulin Polymerization Inhibitors with Potent Antiproliferative Properties H Chen, S Deng, Y Wang, N Albadari, G Kumar, D Ma, W Li, SW White, ... Journal of Medicinal Chemistry 63 (2), 827-846, 2020 | 41 | 2020 |
Combined effect of epigallocatechin gallate and triclosan on enoyl-ACP reductase of Mycobacterium tuberculosis SK Sharma, G Kumar, M Kapoor, A Surolia Biochemical and biophysical research communications 368 (1), 12-17, 2008 | 37 | 2008 |