| Oxidized DNA fragments exit mitochondria via mPTP-and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling H Xian, K Watari, E Sanchez-Lopez, J Offenberger, J Onyuru, H Sampath, ... Immunity 55 (8), 1370-1385. e8, 2022 | 343 | 2022 |
| Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation H Xian, Y Liu, AR Nilsson, R Gatchalian, TR Crother, WG Tourtellotte, ... Immunity 54 (7), 1463-1477. e11, 2021 | 272 | 2021 |
| Reactive oxygen species trigger Parkin/PINK1 pathway–dependent mitophagy by inducing mitochondrial recruitment of Parkin B Xiao, JY Goh, L Xiao, H Xian, KL Lim, YC Liou Journal of Biological Chemistry 292 (40), 16697-16708, 2017 | 228 | 2017 |
| STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism H Xian, Q Yang, L Xiao, HM Shen, YC Liou Nature communications 10 (1), 2059, 2019 | 123 | 2019 |
| Functions of outer mitochondrial membrane proteins: mediating the crosstalk between mitochondrial dynamics and mitophagy H Xian, YC Liou Cell Death & Differentiation 28 (3), 827-842, 2021 | 98 | 2021 |
| Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy H Xian, YC Liou Autophagy 15 (12), 2107-2125, 2019 | 52 | 2019 |
| Death-associated protein 3 regulates mitochondrial-encoded protein synthesis and mitochondrial dynamics L Xiao, H Xian, KY Lee, B Xiao, H Wang, F Yu, HM Shen, YC Liou Journal of Biological Chemistry 290 (41), 24961-24974, 2015 | 45 | 2015 |
| Oxidized mitochondrial DNA: a protective signal gone awry H Xian, M Karin Trends in Immunology 44 (3), 188-200, 2023 | 29 | 2023 |
| IRF1 regulates self-renewal and stress responsiveness to support hematopoietic stem cell maintenance AJS Rundberg Nilsson, H Xian, S Shalapour, J Cammenga, M Karin Science Advances 9 (43), eadg5391, 2023 | 6 | 2023 |
| Author Correction: STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism H Xian, Q Yang, L Xiao, HM Shen, YC Liou Nature communications 12, 2021 | 4 | 2021 |
| Short term metformin intervention inhibits il-6 and il-1β secretion and prevents acute respiratory distress syndrome-implications for Covid-19 H Xian, Y Liu, A Rundberg Nilsson, TR Crother, RA Porrit, ... | 1 | 2020 |
| Mitochondrial DNA oxidation propagates autoimmunity by enabling plasmacytoid dendritic cells induce Tfh differentiation M Karin, H Xian, M Ohira, K Watari, J Brito, J Onyuru, E Zuniga, H Hoffman | | 2024 |
| 3166–IRF1 REGULATES SELF-RENEWAL AND STRESS-RESPONSIVENESS TO SUPPORT HEMATOPOIETIC STEM CELL MAINTENANCE AR Nilsson, H Xian, S Shalapour, J Cammenga, M Karin Experimental Hematology 124, S132, 2023 | | 2023 |
| Author Correction: STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism (Nature Communications,(2019), 10, 1,(2059), 10.1038/s41467 … H Xian, Q Yang, L Xiao, HM Shen, YC Liou Nature Communications 10, 1, 2021 | | 2021 |
| STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism (vol 10, 2059, 2019) H Xian, Q Yang, L Xiao, HM Shen, YC Liou NATURE COMMUNICATIONS 12 (1), 2021 | | 2021 |
| FEN1-Generated Oxidized DNA Fragments Escape Mitochondria via mPTP-and VDAC-Dependent Channels to License NLRP3 Inflammasome and STING Activation H Xian, K Watari, E Sanchez-Lopez, GS Shadel, M Karin Available at SSRN 4022698, 0 | | |
