Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array G Mansell, TJ Gorrie-Stone, Y Bao, M Kumari, LS Schalkwyk, J Mill, ... BMC genomics 20, 1-15, 2019 | 255 | 2019 |
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ... Nature genetics 53 (9), 1311-1321, 2021 | 245 | 2021 |
SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell stem cell 29 (2), 217-231. e8, 2022 | 183 | 2022 |
Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase JA Newman, A Douangamath, S Yadzani, Y Yosaatmadja, A Aimon, ... Nature Communications 12 (1), 4848, 2021 | 161 | 2021 |
Leveraging DNA-methylation quantitative-trait loci to characterize the relationship between methylomic variation, gene expression, and complex traits E Hannon, TJ Gorrie-Stone, MC Smart, J Burrage, A Hughes, Y Bao, ... The American Journal of Human Genetics 103 (5), 654-665, 2018 | 153 | 2018 |
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE Díaz, ID Young, ... Science advances 7 (16), eabf8711, 2021 | 136 | 2021 |
Systematic underestimation of the epigenetic clock and age acceleration in older subjects LY El Khoury, T Gorrie-Stone, M Smart, A Hughes, Y Bao, A Andrayas, ... Genome biology 20, 1-10, 2019 | 92 | 2019 |
Socioeconomic position and DNA methylation age acceleration across the life course A Hughes, M Smart, T Gorrie-Stone, E Hannon, J Mill, Y Bao, J Burrage, ... American journal of epidemiology 187 (11), 2346-2354, 2018 | 83 | 2018 |
Bigmelon: tools for analysing large DNA methylation datasets TJ Gorrie-Stone, MC Smart, A Saffari, K Malki, E Hannon, J Burrage, J Mill, ... Bioinformatics 35 (6), 981-986, 2019 | 54 | 2019 |
COVID moonshot: open science discovery of SARS-CoV-2 main protease inhibitors by combining crowdsourcing, high-throughput experiments, computational simulations, and machine … H Achdout, A Aimon, E Bar-David, GM Morris BioRxiv, 2020 | 48 | 2020 |
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ... BioRxiv, 2020.10. 29.339317, 2020 | 38 | 2020 |
Achieving efficient fragment screening at XChem facility at diamond light source A Douangamath, A Powell, D Fearon, PM Collins, R Talon, T Krojer, ... JoVE (Journal of Visualized Experiments), e62414, 2021 | 33 | 2021 |
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ... Science 382 (6671), eabo7201, 2023 | 31 | 2023 |
Genomic and phenomic insights from an atlas of genetic effects on DNA methylation JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ... MedRxiv, 2020.09. 01.20180406, 2020 | 31 | 2020 |
InterpolatedXY: a two-step strategy to normalize DNA methylation microarray data avoiding sex bias Y Wang, TJ Gorrie-Stone, OA Grant, AD Andrayas, X Zhai, ... Bioinformatics 38 (16), 3950-3957, 2022 | 19 | 2022 |
DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy Y Wang, E Hannon, OA Grant, TJ Gorrie-Stone, M Kumari, J Mill, X Zhai, ... BMC genomics 22 (1), 484, 2021 | 15 | 2021 |
The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations F Åsenius, TJ Gorrie-Stone, A Brew, Y Panchbhaya, E Williamson, ... PLoS genetics 16 (10), e1009035, 2020 | 15 | 2020 |
Tyrosine intake and cardiovascular responses in a motivated performance situation. A Hase, T Gorrie-Stone, P Freeman Sport, Exercise, and Performance Psychology 8 (1), 80, 2019 | 8 | 2019 |
Uncertainty quantification of reference-based cellular deconvolution algorithms DS Vellame, G Shireby, A MacCalman, EL Dempster, J Burrage, ... Epigenetics 18 (1), 2137659, 2023 | 7 | 2023 |
Social mobility across the lifecourse and DNA methylation age acceleration in adults in the UK Y Bao, T Gorrie-Stone, E Hannon, A Hughes, A Andrayas, G Neilson, ... Scientific Reports 12 (1), 22284, 2022 | 7 | 2022 |