Bioavailability and pharmacokinetics of genistein: mechanistic studies on its ADME Z Yang, K Kulkarni, W Zhu, M Hu Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2012 | 212 | 2012 |
Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P‐glycoprotein L Ye, T Wang, L Tang, W Liu, Z Yang, J Zhou, Z Zheng, Z Cai, M Hu, Z Liu Journal of pharmaceutical sciences 100 (11), 5007-5017, 2011 | 146 | 2011 |
Extended-duration MK-8591-eluting implant as a candidate for HIV treatment and prevention SE Barrett, RS Teller, SP Forster, L Li, MA Mackey, D Skomski, Z Yang, ... Antimicrobial agents and chemotherapy 62 (10), 10.1128/aac. 01058-18, 2018 | 139 | 2018 |
Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC–MS/MS method: Application to an oral bioavailability study of … Z Yang, W Zhu, S Gao, H Xu, B Wu, K Kulkarni, R Singh, L Tang, M Hu Journal of pharmaceutical and biomedical analysis 53 (1), 81-89, 2010 | 96 | 2010 |
Temporal interplay between efflux pumps and target mutations in development of antibiotic resistance in Escherichia coli R Singh, MC Swick, KR Ledesma, Z Yang, M Hu, L Zechiedrich, VH Tam Antimicrobial agents and chemotherapy 56 (4), 1680-1685, 2012 | 93 | 2012 |
Disposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides H Xu, KH Kulkarni, R Singh, Z Yang, SWJ Wang, VH Tam, M Hu Molecular pharmaceutics 6 (6), 1703-1715, 2009 | 90 | 2009 |
Breast cancer resistance protein (ABCG2) determines distribution of genistein phase II metabolites: reevaluation of the roles of ABCG2 in the disposition of genistein Z Yang, W Zhu, S Gao, T Yin, W Jiang, M Hu Drug Metabolism and Disposition 40 (10), 1883-1893, 2012 | 86 | 2012 |
Enhancement of Skin Permeation of Bufalin by Limonene via Reservoir Type Transdermal Patch: Formulation Design and Biopharmaceutical Evaluation Z Yang, Y Teng, H Wang, H Hou International Journal of Pharmaceutics, 2013 | 83 | 2013 |
The role of efflux transporters on the transport of highly toxic aconitine, mesaconitine, hypaconitine, and their hydrolysates, as determined in cultured Caco-2 and transfected … L Ye, X Yang, Z Yang, S Gao, T Yin, W Liu, F Wang, M Hu, Z Liu Toxicology Letters 216 (2-3), 86-99, 2013 | 79 | 2013 |
Inhibition of P-glycoprotein leads to improved oral bioavailability of compound K, an anticancer metabolite of red ginseng extract produced by gut microflora Z Yang, JR Wang, T Niu, S Gao, T Yin, M You, ZH Jiang, M Hu Drug Metabolism and Disposition 40 (8), 1538-1544, 2012 | 79 | 2012 |
Enhancement of oral bioavailability of 20 (S)-ginsenoside Rh2 through improved understanding of its absorption and efflux mechanisms Z Yang, S Gao, J Wang, T Yin, Y Teng, B Wu, M You, Z Jiang, M Hu Drug Metabolism and Disposition 39 (10), 1866-1872, 2011 | 77 | 2011 |
Bioavailability challenges associated with development of saponins as therapeutic and chemopreventive agents S Gao, S Basu, Z Yang, A Deb, M Hu Current drug targets 13 (14), 1885-1899, 2012 | 75 | 2012 |
Sensitive and robust UPLC–MS/MS method to determine the gender-dependent pharmacokinetics in rats of emodin and its glucuronide W Liu, Z Zheng, X Liu, S Gao, L Ye, Z Yang, M Hu, Z Liu Journal of Pharmaceutical and Biomedical Analysis 54 (5), 1157-1162, 2011 | 64 | 2011 |
Biopharmaceutical and pharmacokinetic characterization of matrine as determined by a sensitive and robust UPLC–MS/MS method Z Yang, S Gao, T Yin, KH Kulkarni, Y Teng, M You, M Hu Journal of pharmaceutical and biomedical analysis 51 (5), 1120-1127, 2010 | 64 | 2010 |
Bioactivity and Bioavailability of Ginsenosides are Dependent on the Glycosidase Activities of the A/J Mouse Intestinal Microbiome Defined by Pyrosequencing. T Niu, DL Smith, Z Yang, S Gao, T Yin, ZH Jiang, M You, RA Gibbs, ... Pharmaceutical research, 2012 | 62 | 2012 |
Ginsenoside Rb1 Directly Scavenges Hydroxyl Radical and Hypochlorous Acid. JM Lü, S Weakley, Z Yang, M Hu, Q Yao, C Chen Current pharmaceutical design, 2012 | 52 | 2012 |
Rapid and simultaneous determination of multiple classes of abused drugs and metabolites in human urine by a robust LC‐MS/MS method–application to urine drug testing in pain … J Wang, Z Yang, J Lechago Biomedical Chromatography 27 (11), 1463-1480, 2013 | 43 | 2013 |
Preparative isolation of bufalin and cinobufagin from Chinese traditional medicine ChanSu Z Yang, H Luo, H Wang, H Hou Journal of chromatographic science 46 (1), 81-85, 2008 | 43 | 2008 |
Development of a novel oral cavity compartmental absorption and transit model for sublingual administration: illustration with zolpidem B Xia, Z Yang, H Zhou, V Lukacova, W Zhu, M Milewski, F Kesisoglou The AAPS journal 17, 631-642, 2015 | 34 | 2015 |
Validated LC–MS/MS method for the determination of maackiain and its sulfate and glucuronide in blood: Application to pharmacokinetic and disposition studies S Gao, Z Yang, T Yin, M You, M Hu Journal of pharmaceutical and biomedical analysis 55 (2), 288-293, 2011 | 28 | 2011 |