Role of biomechanics in intervertebral disc degeneration and regenerative therapies: what needs repairing in the disc and what are promising biomaterials for its repair? JC Iatridis, SB Nicoll, AJ Michalek, BA Walter, MS Gupta The Spine Journal 13 (3), 243-262, 2013 | 348 | 2013 |
Complex loading affects intervertebral disc mechanics and biology BA Walter, CL Korecki, D Purmessur, PJ Roughley, AJ Michalek, ... Osteoarthritis and cartilage 19 (8), 1011-1018, 2011 | 235 | 2011 |
Genipin-crosslinked fibrin hydrogels as a potential adhesive to augment intervertebral disc annulus repair RM Schek, AJ Michalek, JC Iatridis European cells & materials 21, 373, 2011 | 180 | 2011 |
Measurement of local strains in intervertebral disc anulus fibrosus tissue under dynamic shear: contributions of matrix fiber orientation and elastin content AJ Michalek, MR Buckley, LJ Bonassar, I Cohen, JC Iatridis Journal of biomechanics 42 (14), 2279-2285, 2009 | 135 | 2009 |
The effects of needle puncture injury on microscale shear strain in the intervertebral disc annulus fibrosus AJ Michalek, MR Buckley, LJ Bonassar, I Cohen, JC Iatridis The Spine Journal 10 (12), 1098-1105, 2010 | 119 | 2010 |
Needle puncture injury of the rat intervertebral disc affects torsional and compressive biomechanics differently AJ Michalek, KL Funabashi, JC Iatridis European Spine Journal 19, 2110-2116, 2010 | 109 | 2010 |
Phosphorylation and calcium antagonistically tune myosin-binding protein C’s structure and function MJ Previs, JY Mun, AJ Michalek, SB Previs, J Gulick, J Robbins, ... Proceedings of the National Academy of Sciences 113 (12), 3239-3244, 2016 | 106 | 2016 |
Localized intervertebral disc injury leads to organ level changes in structure, cellularity, and biosynthesis JC Iatridis, AJ Michalek, D Purmessur, CL Korecki Cellular and molecular bioengineering 2, 437-447, 2009 | 102 | 2009 |
Height and torsional stiffness are most sensitive to annular injury in large animal intervertebral discs AJ Michalek, JC Iatridis The Spine Journal 12 (5), 425-432, 2012 | 89 | 2012 |
Effects of enzymatic digestion on compressive properties of rat intervertebral discs A Barbir, AJ Michalek, RD Abbott, JC Iatridis Journal of biomechanics 43 (6), 1067-1073, 2010 | 88 | 2010 |
Analysis of quantitative magnetic resonance imaging and biomechanical parameters on human discs with different grades of degeneration J Antoniou, LM Epure, AJ Michalek, MP Grant, JC Iatridis, F Mwale Journal of Magnetic Resonance Imaging 38 (6), 1402-1414, 2013 | 86 | 2013 |
Effects of torsion on intervertebral disc gene expression and biomechanics, using a rat tail model A Barbir, KE Godburn, AJ Michalek, A Lai, RD Monsey, JC Iatridis Spine 36 (8), 607-614, 2011 | 84 | 2011 |
Different effects of static versus cyclic compressive loading on rat intervertebral disc height and water loss in vitro K Masuoka, AJ Michalek, JJ MacLean, IAF Stokes, JC Iatridis Spine 32 (18), 1974-1979, 2007 | 77 | 2007 |
Large residual strains are present in the intervertebral disc annulus fibrosus in the unloaded state AJ Michalek, MG Gardner-Morse, JC Iatridis Journal of biomechanics 45 (7), 1227-1231, 2012 | 72 | 2012 |
Evaluation of quantitative magnetic resonance imaging, biochemical and mechanical properties of trypsin‐treated intervertebral discs under physiological compression loading F Mwale, CN Demers, AJ Michalek, G Beaudoin, T Goswami, L Beckman, ... Journal of Magnetic Resonance Imaging: An Official Journal of the …, 2008 | 62 | 2008 |
Phosphorylation modulates the mechanical stability of the cardiac myosin-binding protein C motif AJ Michalek, JW Howarth, J Gulick, MJ Previs, J Robbins, PR Rosevear, ... Biophysical journal 104 (2), 442-452, 2013 | 34 | 2013 |
Penetrating annulus fibrosus injuries affect dynamic compressive behaviors of the intervertebral disc via altered fluid flow: an analytical interpretation AJ Michalek, JC Iatridis | 33 | 2011 |
Residual strains in the intervertebral disc annulus fibrosus suggest complex tissue remodeling in response to in-vivo loading SE Duclos, AJ Michalek Journal of the mechanical behavior of biomedical materials 68, 232-238, 2017 | 31 | 2017 |
Molecular modulation of actomyosin function by cardiac myosin-binding protein C MJ Previs, AJ Michalek, DM Warshaw Pflügers Archiv-European Journal of Physiology 466, 439-444, 2014 | 31 | 2014 |
A numerical study to determine pericellular matrix modulus and evaluate its effects on the micromechanical environment of chondrocytes AJ Michalek, JC Iatridis Journal of biomechanics 40 (6), 1405-1409, 2007 | 31 | 2007 |