关注
Ayesha A Shafi
Ayesha A Shafi
Assistant Professor, Center for Prostate Disease Research (CPDR), Uniformed Services University;
在 cpdr.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
Androgen receptors in hormone-dependent and castration-resistant prostate cancer
AA Shafi, AE Yen, NL Weigel
Pharmacology & therapeutics 140 (3), 223-238, 2013
4262013
Cancer and the circadian clock
AA Shafi, KE Knudsen
Cancer research 79 (15), 3806-3814, 2019
1962019
Androgen receptor and its splice variant, AR-V7, differentially regulate FOXA1 sensitive genes in LNCaP prostate cancer cells
WC Krause, AA Shafi, M Nakka, NL Weigel
The international journal of biochemistry & cell biology 54, 49-59, 2014
992014
Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells
AA Shafi, V Putluri, JM Arnold, E Tsouko, S Maity, JM Roberts, C Coarfa, ...
Oncotarget 6 (31), 31997, 2015
932015
The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair
AA Shafi, CM McNair, JJ McCann, M Alshalalfa, A Shostak, TM Severson, ...
Nature communications 12 (1), 401, 2021
742021
Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression
S He, C Zhang, AA Shafi, M Sequeira, J Acquaviva, JC Friedland, J Sang, ...
International journal of oncology 42 (1), 35-43, 2013
742013
PARP‐1 regulates DNA repair factor availability
MJ Schiewer, AC Mandigo, N Gordon, F Huang, S Gaur, R de Leeuw, ...
EMBO molecular medicine 10 (12), e8816, 2018
672018
Androgen receptor splice variants are resistant to inhibitors of Hsp90 and FKBP52, which alter androgen receptor activity and expression
AA Shafi, MB Cox, NL Weigel
Steroids 78 (6), 548-554, 2013
662013
USP22 functions as an oncogenic driver in prostate cancer by regulating cell proliferation and DNA repair
JJ McCann, IA Vasilevskaya, N Poudel Neupane, AA Shafi, C McNair, ...
Cancer research 80 (3), 430-443, 2020
522020
RB/E2F1 as a master regulator of cancer cell metabolism in advanced disease
AC Mandigo, W Yuan, K Xu, P Gallagher, A Pang, YF Guan, AA Shafi, ...
Cancer discovery 11 (9), 2334-2353, 2021
512021
Patient-derived models reveal impact of the tumor microenvironment on therapeutic response
AA Shafi, MJ Schiewer, R de Leeuw, E Dylgjeri, PA McCue, N Shah, ...
European urology oncology 1 (4), 325-337, 2018
462018
Pleiotropic impact of DNA-PK in cancer and implications for therapeutic strategies
E Dylgjeri, C McNair, JF Goodwin, HK Raymon, PA McCue, AA Shafi, ...
Clinical Cancer Research 25 (18), 5623-5637, 2019
312019
Cistrome and transcriptome analysis identifies unique androgen receptor (AR) and AR-V7 splice variant chromatin binding and transcriptional activities
P Basil, MJ Robertson, WE Bingman III, AK Dash, WC Krause, AA Shafi, ...
Scientific reports 12 (1), 5351, 2022
172022
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes
JJ McCann, IA Vasilevskaya, C McNair, P Gallagher, NP Neupane, ...
Oncogene 41 (3), 444-458, 2022
172022
A novel role for DNA-PK in metabolism by regulating glycolysis in castration-resistant prostate cancer
E Dylgjeri, V Kothari, AA Shafi, G Semenova, PT Gallagher, YF Guan, ...
Clinical Cancer Research 28 (7), 1446-1459, 2022
162022
Novel oncogenic transcription factor cooperation in RB-deficient cancer
AC Mandigo, AA Shafi, JJ McCann, W Yuan, TS Laufer, D Bogdan, ...
Cancer Research 82 (2), 221-234, 2022
102022
Randomized Phase II Multicenter Trial of Abiraterone Acetate With or Without Cabazitaxel in the Treatment of Metastatic Castration-Resistant Prostate Cancer
SF Slovin, K Knudsen, S Halabi, R de Leeuw, A Shafi, P Kang, S Wolf, ...
Journal of Clinical Oncology 41 (32), 5015-5024, 2023
22023
Time Matters: Importance of Circadian Rhythms, Disruption, and Chronotherapy in Urologic Malignancies
ST Pence, GT Chesnut, AA Shafi
Urology 175, 6-12, 2023
22023
PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer
N Gordon, PT Gallagher, NP Neupane, AC Mandigo, JK McCann, ...
bioRxiv, 2023
12023
Circadian clock gene expression and lethal prostate cancer outcomes
SC Markt, E Ebot, I Cheng, L Wilkens, A Shafi, K Knudsen, K Penney, ...
Cancer Research 79 (13_Supplement), 1574-1574, 2019
12019
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