Androgen receptors in hormone-dependent and castration-resistant prostate cancer AA Shafi, AE Yen, NL Weigel Pharmacology & therapeutics 140 (3), 223-238, 2013 | 426 | 2013 |
Cancer and the circadian clock AA Shafi, KE Knudsen Cancer research 79 (15), 3806-3814, 2019 | 196 | 2019 |
Androgen receptor and its splice variant, AR-V7, differentially regulate FOXA1 sensitive genes in LNCaP prostate cancer cells WC Krause, AA Shafi, M Nakka, NL Weigel The international journal of biochemistry & cell biology 54, 49-59, 2014 | 99 | 2014 |
Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells AA Shafi, V Putluri, JM Arnold, E Tsouko, S Maity, JM Roberts, C Coarfa, ... Oncotarget 6 (31), 31997, 2015 | 93 | 2015 |
The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair AA Shafi, CM McNair, JJ McCann, M Alshalalfa, A Shostak, TM Severson, ... Nature communications 12 (1), 401, 2021 | 74 | 2021 |
Potent activity of the Hsp90 inhibitor ganetespib in prostate cancer cells irrespective of androgen receptor status or variant receptor expression S He, C Zhang, AA Shafi, M Sequeira, J Acquaviva, JC Friedland, J Sang, ... International journal of oncology 42 (1), 35-43, 2013 | 74 | 2013 |
PARP‐1 regulates DNA repair factor availability MJ Schiewer, AC Mandigo, N Gordon, F Huang, S Gaur, R de Leeuw, ... EMBO molecular medicine 10 (12), e8816, 2018 | 67 | 2018 |
Androgen receptor splice variants are resistant to inhibitors of Hsp90 and FKBP52, which alter androgen receptor activity and expression AA Shafi, MB Cox, NL Weigel Steroids 78 (6), 548-554, 2013 | 66 | 2013 |
USP22 functions as an oncogenic driver in prostate cancer by regulating cell proliferation and DNA repair JJ McCann, IA Vasilevskaya, N Poudel Neupane, AA Shafi, C McNair, ... Cancer research 80 (3), 430-443, 2020 | 52 | 2020 |
RB/E2F1 as a master regulator of cancer cell metabolism in advanced disease AC Mandigo, W Yuan, K Xu, P Gallagher, A Pang, YF Guan, AA Shafi, ... Cancer discovery 11 (9), 2334-2353, 2021 | 51 | 2021 |
Patient-derived models reveal impact of the tumor microenvironment on therapeutic response AA Shafi, MJ Schiewer, R de Leeuw, E Dylgjeri, PA McCue, N Shah, ... European urology oncology 1 (4), 325-337, 2018 | 46 | 2018 |
Pleiotropic impact of DNA-PK in cancer and implications for therapeutic strategies E Dylgjeri, C McNair, JF Goodwin, HK Raymon, PA McCue, AA Shafi, ... Clinical Cancer Research 25 (18), 5623-5637, 2019 | 31 | 2019 |
Cistrome and transcriptome analysis identifies unique androgen receptor (AR) and AR-V7 splice variant chromatin binding and transcriptional activities P Basil, MJ Robertson, WE Bingman III, AK Dash, WC Krause, AA Shafi, ... Scientific reports 12 (1), 5351, 2022 | 17 | 2022 |
Mutant p53 elicits context-dependent pro-tumorigenic phenotypes JJ McCann, IA Vasilevskaya, C McNair, P Gallagher, NP Neupane, ... Oncogene 41 (3), 444-458, 2022 | 17 | 2022 |
A novel role for DNA-PK in metabolism by regulating glycolysis in castration-resistant prostate cancer E Dylgjeri, V Kothari, AA Shafi, G Semenova, PT Gallagher, YF Guan, ... Clinical Cancer Research 28 (7), 1446-1459, 2022 | 16 | 2022 |
Novel oncogenic transcription factor cooperation in RB-deficient cancer AC Mandigo, AA Shafi, JJ McCann, W Yuan, TS Laufer, D Bogdan, ... Cancer Research 82 (2), 221-234, 2022 | 10 | 2022 |
Randomized Phase II Multicenter Trial of Abiraterone Acetate With or Without Cabazitaxel in the Treatment of Metastatic Castration-Resistant Prostate Cancer SF Slovin, K Knudsen, S Halabi, R de Leeuw, A Shafi, P Kang, S Wolf, ... Journal of Clinical Oncology 41 (32), 5015-5024, 2023 | 2 | 2023 |
Time Matters: Importance of Circadian Rhythms, Disruption, and Chronotherapy in Urologic Malignancies ST Pence, GT Chesnut, AA Shafi Urology 175, 6-12, 2023 | 2 | 2023 |
PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer N Gordon, PT Gallagher, NP Neupane, AC Mandigo, JK McCann, ... bioRxiv, 2023 | 1 | 2023 |
Circadian clock gene expression and lethal prostate cancer outcomes SC Markt, E Ebot, I Cheng, L Wilkens, A Shafi, K Knudsen, K Penney, ... Cancer Research 79 (13_Supplement), 1574-1574, 2019 | 1 | 2019 |