| Structure and orientation of the mammalian antibacterial peptide cecropin P1 within phospholipid membranes E Gazit, IR Miller, PC Biggin, MSP Sansom, Y Shai Journal of molecular biology 258 (5), 860-870, 1996 | 371 | 1996 |
| A hydrophobic gating mechanism for nanopores O Beckstein, PC Biggin, MSP Sansom The Journal of Physical Chemistry B 105 (51), 12902-12905, 2001 | 336 | 2001 |
| Accurate calculation of the absolute free energy of binding for drug molecules M Aldeghi, A Heifetz, MJ Bodkin, S Knapp, PC Biggin Chemical science 7 (1), 207-218, 2016 | 312 | 2016 |
| Insect GABA receptors: splicing, editing, and targeting by antiparasitics and insecticides SD Buckingham, PC Biggin, BM Sattelle, LA Brown, DB Sattelle Molecular pharmacology 68 (4), 942-951, 2005 | 262 | 2005 |
| Simulation approaches to ion channel structure-function relationships. DP Tieleman, PC Biggin, GR Smith, MS Sansom Quaterley Reviews in Biophysics 34 (4), 473-561, 2001 | 249 | 2001 |
| Potassium channels: structures, models, simulations MSP Sansom, IH Shrivastava, JN Bright, J Tate, CE Capener, PC Biggin Biochimica et Biophysica Acta (BBA)-Biomembranes 1565 (2), 294-307, 2002 | 235 | 2002 |
| The 3-dimensional structure of a hepatitis C virus p7 ion channel by electron microscopy P Luik, C Chew, J Aittoniemi, J Chang, P Wentworth Jr, RA Dwek, ... Proceedings of the National Academy of Sciences 106 (31), 12712-12716, 2009 | 214 | 2009 |
| Rapid and accurate prediction and scoring of water molecules in protein binding sites GA Ross, GM Morris, PC Biggin PloS one 7 (3), e32036, 2012 | 209 | 2012 |
| K+ versus Na+ ions in a K channel selectivity filter: a simulation study IH Shrivastava, DP Tieleman, PC Biggin, MSP Sansom Biophysical journal 83 (2), 633-645, 2002 | 192 | 2002 |
| Edit, cut and paste in the nicotinic acetylcholine receptor gene family of Drosophila melanogaster DB Sattelle, AK Jones, BM Sattelle, K Matsuda, R Reenan, PC Biggin Bioessays 27 (4), 366-376, 2005 | 191 | 2005 |
| Water at the nanoscale MSP Sansom, PC Biggin Nature 414 (6860), 157-159, 2001 | 190 | 2001 |
| Crystal structures of a GABAA-receptor chimera reveal new endogenous neurosteroid-binding sites D Laverty, P Thomas, M Field, OJ Andersen, MG Gold, PC Biggin, ... Nature structural & molecular biology 24 (11), 977-985, 2017 | 188 | 2017 |
| Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump J Marcoux, SC Wang, A Politis, E Reading, J Ma, PC Biggin, M Zhou, ... Proceedings of the National Academy of Sciences 110 (24), 9704-9709, 2013 | 186 | 2013 |
| Simulation studies of the interaction of antimicrobial peptides and lipid bilayers P La Rocca, PC Biggin, DP Tieleman, MSP Sansom Biochimica et Biophysica Acta (BBA)-Biomembranes 1462 (1-2), 185-200, 1999 | 173 | 1999 |
| Ion channel gating: insights via molecular simulations O Beckstein, PC Biggin, P Bond, JN Bright, C Domene, A Grottesi, ... FEBS letters 555 (1), 85-90, 2003 | 161 | 2003 |
| Predictive low-glucose insulin suspension reduces duration of nocturnal hypoglycemia in children without increasing ketosis BA Buckingham, D Raghinaru, F Cameron, BW Bequette, HP Chase, ... Diabetes Care 38 (7), 1197-1204, 2015 | 157 | 2015 |
| Predictions of ligand selectivity from absolute binding free energy calculations M Aldeghi, A Heifetz, MJ Bodkin, S Knapp, PC Biggin Journal of the American Chemical Society 139 (2), 946-957, 2017 | 156 | 2017 |
| Interactions of α-helices with lipid bilayers: a review of simulation studies PC Biggin, MSP Sansom Biophysical chemistry 76 (3), 161-183, 1999 | 156 | 1999 |
| Towards understanding promiscuity in multidrug efflux pumps K Wong, J Ma, A Rothnie, PC Biggin, ID Kerr Trends in biochemical sciences 39 (1), 8-16, 2014 | 153 | 2014 |
| Biomolecular simulations: From dynamics and mechanisms to computational assays of biological activity DJ Huggins, PC Biggin, MA Dämgen, JW Essex, SA Harris, ... Wiley Interdisciplinary Reviews: Computational Molecular Science 9 (3), e1393, 2019 | 152 | 2019 |
