Selvamicin, an atypical antifungal polyene from two alternative genomic contexts EB Van Arnam, AC Ruzzini, CS Sit, H Horn, AA Pinto-Tomás, CR Currie, ... Proceedings of the National Academy of Sciences 113 (46), 12940-12945, 2016 | 126 | 2016 |
Variable genetic architectures produce virtually identical molecules in bacterial symbionts of fungus-growing ants CS Sit, AC Ruzzini, EB Van Arnam, TR Ramadhar, CR Currie, J Clardy Proceedings of the National Academy of Sciences 112 (43), 13150-13154, 2015 | 109 | 2015 |
Pyrazines from bacteria and ants: convergent chemistry within an ecological niche EA Silva-Junior, AC Ruzzini, CR Paludo, FS Nascimento, CR Currie, ... Scientific reports 8 (1), 2595, 2018 | 74 | 2018 |
A rebeccamycin analog provides plasmid-encoded niche defense EB Van Arnam, AC Ruzzini, CS Sit, CR Currie, J Clardy Journal of the American Chemical Society 137 (45), 14272-14274, 2015 | 57 | 2015 |
Tryptorubin A: A polycyclic peptide from a fungus-derived streptomycete TP Wyche, AC Ruzzini, L Schwab, CR Currie, J Clardy Journal of the American Chemical Society 139 (37), 12899-12902, 2017 | 48 | 2017 |
Identification of an Acyl-Enzyme Intermediate in a meta-Cleavage Product Hydrolase Reveals the Versatility of the Catalytic Triad AC Ruzzini, S Ghosh, GP Horsman, LJ Foster, JT Bolin, LD Eltis Journal of the American Chemical Society 134 (10), 4615-4624, 2012 | 39 | 2012 |
Linear peptides are the major products of a biosynthetic pathway that encodes for cyclic depsipeptides TP Wyche, AC Ruzzini, C Beemelmanns, KH Kim, JL Klassen, S Cao, ... Organic letters 19 (7), 1772-1775, 2017 | 38 | 2017 |
The impact of nitric oxide toxicity on the evolution of the glutathione transferase superfamily: a proposal for an evolutionary driving force A Bocedi, R Fabrini, A Farrotti, L Stella, AJ Ketterman, JZ Pedersen, ... Journal of Biological Chemistry 288 (34), 24936-24947, 2013 | 34 | 2013 |
Gene flow and molecular innovation in bacteria AC Ruzzini, J Clardy Current Biology 26 (18), R859-R864, 2016 | 31 | 2016 |
A P450 fusion library of heme domains from Rhodococcus jostii RHA1 and its evaluation for the biotransformation of drug molecules JK Kulig, C Spandolf, R Hyde, AC Ruzzini, LD Eltis, G Grönberg, ... Bioorganic & medicinal chemistry 23 (17), 5603-5609, 2015 | 26 | 2015 |
Investigation of Macrolide Resistance Genotypes in Mycoplasma bovis Isolates from Canadian Feedlot Cattle A Kinnear, TA McAllister, R Zaheer, M Waldner, AC Ruzzini, ... Pathogens 9 (8), 622, 2020 | 22 | 2020 |
Metabolites Involved in Immune Evasion by Batrachochytrium dendrobatidis Include the Polyamine Spermidine LA Rollins-Smith, AC Ruzzini, JS Fites, LK Reinert, EM Hall, BA Joosse, ... Infection and immunity 87 (5), 10.1128/iai. 00035-19, 2019 | 22 | 2019 |
The Catalytic Serine of meta-Cleavage Product Hydrolases Is Activated Differently for C–O Bond Cleavage Than for C–C Bond Cleavage AC Ruzzini, GP Horsman, LD Eltis Biochemistry 51 (29), 5831-5840, 2012 | 21 | 2012 |
Evaluating approved and alternative treatments against an oxytetracycline-resistant bacterium responsible for European foulbrood disease in honey bees F Masood, JM Thebeau, A Cloet, IV Kozii, MW Zabrodski, S Biganski, ... Scientific Reports 12 (1), 5906, 2022 | 17 | 2022 |
A substrate-assisted mechanism of nucleophile activation in a Ser–His–Asp containing C–C bond hydrolase AC Ruzzini, S Bhowmik, S Ghosh, KC Yam, JT Bolin, LD Eltis Biochemistry 52 (42), 7428-7438, 2013 | 17 | 2013 |
Whole-Genome Sequence of Bacillus sp. SDLI1, Isolated from the Social Bee Scaptotrigona depilis CR Paludo, AC Ruzzini, EA Silva-Junior, G Pishchany, CR Currie, ... Genome announcements 4 (2), 10.1128/genomea. 00174-16, 2016 | 16 | 2016 |
Evaluation of drugs and stationary growth on the cell cycle of Giardia intestinalis C Reaume, B Moore, P Hernández, A Ruzzini, M Chlebus, M Wasserman, ... Molecular and biochemical parasitology 187 (1), 72-76, 2013 | 15 | 2013 |
Study of bicyclomycin biosynthesis in Streptomyces cinnamoneus by genetic and biochemical approaches J Witwinowski, M Moutiez, M Coupet, I Correia, P Belin, A Ruzzini, ... Scientific Reports 9 (1), 20226, 2019 | 13 | 2019 |
Biogeography and Microscale Diversity Shape the Biosynthetic Potential of Fungus-growing Ant-associated Pseudonocardia BR McDonald, MG Chevrette, JL Klassen, HA Horn, EJ Caldera, ... BioRxiv, 545640, 2019 | 13 | 2019 |
The lid domain of the MCP hydrolase DxnB2 contributes to the reactivity toward recalcitrant PCB metabolites AC Ruzzini, S Bhowmik, KC Yam, S Ghosh, JT Bolin, LD Eltis Biochemistry 52 (33), 5685-5695, 2013 | 13 | 2013 |