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Hanns-Christian Mahler
Hanns-Christian Mahler
apl Prof, Pharmazeutische Technologie, Universität Frankfurt/M
在 lonza.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Protein aggregation: pathways, induction factors and analysis
HC Mahler, W Friess, U Grauschopf, S Kiese
Journal of pharmaceutical sciences 98 (9), 2909-2934, 2009
10022009
Shaken, not stirred: mechanical stress testing of an IgG1 antibody
S Kiese, A Papppenberger, W Friess, HC Mahler
Journal of pharmaceutical sciences 97 (10), 4347-4366, 2008
4582008
An industry perspective on the monitoring of subvisible particles as a quality attribute for protein therapeutics
SK Singh, N Afonina, M Awwad, K Bechtold-Peters, JT Blue, D Chou, ...
Journal of pharmaceutical sciences 99 (8), 3302-3321, 2010
3532010
Induction and analysis of aggregates in a liquid IgG1-antibody formulation
HC Mahler, R Müller, W Frieβ, A Delille, S Matheus
European journal of pharmaceutics and biopharmaceutics 59 (3), 407-417, 2005
3452005
Degradation of polysorbates 20 and 80: studies on thermal autoxidation and hydrolysis
RSK Kishore, A Pappenberger, IB Dauphin, A Ross, B Buergi, A Staempfli, ...
Journal of pharmaceutical sciences 100 (2), 721-731, 2011
2992011
The degradation of polysorbates 20 and 80 and its potential impact on the stability of biotherapeutics
RSK Kishore, S Kiese, S Fischer, A Pappenberger, U Grauschopf, ...
Pharmaceutical research 28, 1194-1210, 2011
2892011
Forced degradation of therapeutic proteins
A Hawe, M Wiggenhorn, M van de Weert, JHO Garbe, H Mahler, ...
Journal of pharmaceutical sciences 101 (3), 895-913, 2012
2772012
Key interactions of surfactants in therapeutic protein formulations: a review
TA Khan, HC Mahler, RSK Kishore
European journal of pharmaceutics and biopharmaceutics 97, 60-67, 2015
2442015
Assessment of net charge and protein–protein interactions of different monoclonal antibodies
C Lehermayr, HC Mahler, K Mäder, S Fischer
Journal of pharmaceutical sciences 100 (7), 2551-2562, 2011
2162011
FTIR and nDSC as analytical tools for high-concentration protein formulations
S Matheus, W Friess, HC Mahler
Pharmaceutical research 23, 1350-1363, 2006
1502006
Freeze drying of human serum albumin (HSA) nanoparticles with different excipients
MG Anhorn, HC Mahler, K Langer
International journal of pharmaceutics 363 (1-2), 162-169, 2008
1452008
Subcutaneous injection volume of biopharmaceuticals—pushing the boundaries
R Mathaes, A Koulov, S Joerg, HC Mahler
Journal of pharmaceutical sciences 105 (8), 2255-2259, 2016
1392016
Glycation during storage and administration of monoclonal antibody formulations
S Fischer, J Hoernschemeyer, HC Mahler
European Journal of Pharmaceutics and Biopharmaceutics 70 (1), 42-50, 2008
1292008
Rheological characterization and injection forces of concentrated protein formulations: an alternative predictive model for non-Newtonian solutions
A Allmendinger, S Fischer, J Huwyler, HC Mahler, E Schwarb, IE Zarraga, ...
European journal of pharmaceutics and biopharmaceutics 87 (2), 318-328, 2014
1112014
Surface activity of a monoclonal antibody
HC Mahler, F Senner, K Maeder, R Mueller
Journal of pharmaceutical sciences 98 (12), 4525-4533, 2009
1112009
Highly Concentrated Pharmaceutical Formulations
M Adler, HC Mahler, OB Stauch
US Patent App. 12/879,486, 2011
1092011
Oxidative DNA damage and mutations induced by a polar photosensitizer, Ro19-8022
O Will, E Gocke, I Eckert, I Schulz, M Pflaum, HC Mahler, B Epe
Mutation Research/DNA Repair 435 (1), 89-101, 1999
1091999
Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic I g G 1 Molecule
E Folzer, K Diepold, K Bomans, C Finkler, R Schmidt, P Bulau, ...
Journal of pharmaceutical sciences 104 (9), 2824-2831, 2015
1052015
Mouse models for assessing protein immunogenicity: lessons and challenges
W Jiskoot, G Kijanka, TW Randolph, JF Carpenter, AV Koulov, HC Mahler, ...
Journal of pharmaceutical sciences 105 (5), 1567-1575, 2016
1042016
Adsorption behavior of a surfactant and a monoclonal antibody to sterilizing-grade filters
HC Mahler, F Huber, RSK Kishore, J Reindl, P Rückert, R Müller
Journal of pharmaceutical sciences 99 (6), 2620-2627, 2010
982010
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