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New directions in ER stress-induced cell death SE Logue, P Cleary, S Saveljeva, A Samali Apoptosis 18, 537-546, 2013 | 316 | 2013 |
Stress-induced self-cannibalism: on the regulation of autophagy by endoplasmic reticulum stress S Deegan, S Saveljeva, AM Gorman, A Samali Cellular and Molecular Life Sciences 70, 2425-2441, 2013 | 312 | 2013 |
Defective ATG16L1-mediated removal of IRE1α drives Crohn’s disease–like ileitis M Tschurtschenthaler, TE Adolph, JW Ashcroft, L Niederreiter, R Bharti, ... Journal of Experimental Medicine 214 (2), 401-422, 2017 | 171 | 2017 |
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015. 1100356 DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Erratum to: Guidelines for the use and interpretation of assays for …, 2016 | 158 | 2016 |
C13orf31 (FAMIN) is a central regulator of immunometabolic function MZ Cader, K Boroviak, Q Zhang, G Assadi, SL Kempster, GW Sewell, ... Nature immunology 17 (9), 1046-1056, 2016 | 150 | 2016 |
Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells S Saveljeva, SL Mc Laughlin, P Vandenabeele, A Samali, MJM Bertrand Cell death & disease 6 (1), e1587-e1587, 2015 | 146 | 2015 |
ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING K Aden, F Tran, GO Ito, R Sheibani-Tezerji, S Lipinski, JW Kuiper, ... Journal of Experimental Medicine 215 (11), 2868-2886, 2018 | 137 | 2018 |
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells N Powell, E Pantazi, P Pavlidis, A Tsakmaki, K Li, F Yang, A Parker, C Pin, ... Gut 69 (3), 578-590, 2020 | 98 | 2020 |
Endoplasmic reticulum stress-mediated induction of SESTRIN 2 potentiates cell survival S Saveljeva, P Cleary, K Mnich, A Ayo, K Pakos-Zebrucka, JB Patterson, ... Oncotarget 7 (11), 12254, 2016 | 81 | 2016 |
GPR35 promotes glycolysis, proliferation, and oncogenic signaling by engaging with the sodium potassium pump G Schneditz, JE Elias, E Pagano, M Zaeem Cader, S Saveljeva, K Long, ... Science signaling 12 (562), eaau9048, 2019 | 76 | 2019 |
Epithelial endoplasmic reticulum stress orchestrates a protective IgA response J Grootjans, N Krupka, S Hosomi, JD Matute, T Hanley, S Saveljeva, ... Science 363 (6430), 993-998, 2019 | 57 | 2019 |
Deficiency in the mitochondrial apoptotic pathway reveals the toxic potential of autophagy under ER stress conditions S Deegan, S Saveljeva, SE Logue, K Pakos-Zebrucka, S Gupta, ... Autophagy 10 (11), 1921-1936, 2014 | 56 | 2014 |
Activation of the GPR35 pathway drives angiogenesis in the tumour microenvironment E Pagano, JE Elias, G Schneditz, S Saveljeva, LM Holland, F Borrelli, ... Gut 71 (3), 509-520, 2022 | 55 | 2022 |
FAMIN is a multifunctional purine enzyme enabling the purine nucleotide cycle MZ Cader, RP de Almeida Rodrigues, JA West, GW Sewell, ... Cell 180 (2), 278-295. e23, 2020 | 50 | 2020 |
HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis D Kennedy, K Mnich, D Oommen, R Chakravarthy, L Almeida-Souza, ... Cell Death & Disease 8 (8), e3026-e3026, 2017 | 40 | 2017 |
Impaired Autophagy in CD11b+ Dendritic Cells Expands CD4+ Regulatory T Cells and Limits Atherosclerosis in Mice M Clement, J Raffort, F Lareyre, D Tsiantoulas, S Newland, Y Lu, ... Circulation Research 125 (11), 1019-1034, 2019 | 34 | 2019 |
A purine metabolic checkpoint that prevents autoimmunity and autoinflammation S Saveljeva, GW Sewell, K Ramshorn, MZ Cader, JA West, S Clare, ... Cell metabolism 34 (1), 106-124. e10, 2022 | 27 | 2022 |
ER stress responses in the absence of apoptosome: A comparative study in CASP9 proficient vs deficient mouse embryonic fibroblasts S Deegan, S Saveljeva, S Gupta, DC MacDonald, A Samali Biochemical and biophysical research communications 451 (3), 367-373, 2014 | 5 | 2014 |
LOSS OF AUTOPHAGY IN DENDRITIC CELLS PROMOTES CD4 (+) TREG EXPANSION AND LIMITS THE DEVELOPMENT OF ATHEROSCLEROSIS IN MICE M Clement, F Lareyre, J Raffort, S Saveljeva, L Masters, S Newland, ... CARDIOVASCULAR RESEARCH 114, S1-S1, 2018 | | 2018 |