Insights into the unique phosphorylation of the lasso peptide paeninodin S Zhu, JD Hegemann, CD Fage, M Zimmermann, X Xie, U Linne, ... Journal of Biological Chemistry 291 (26), 13662-13678, 2016 | 136 | 2016 |
Catalytic mechanism and allosteric regulation of an oligomeric (p) ppGpp synthetase by an alarmone W Steinchen, JS Schuhmacher, F Altegoer, CD Fage, V Srinivasan, ... Proceedings of the National Academy of Sciences 112 (43), 13348-13353, 2015 | 130 | 2015 |
The structure of SpnF, a standalone enzyme that catalyzes [4+ 2] cycloaddition CD Fage, EA Isiorho, Y Liu, DT Wagner, H Liu, AT Keatinge-Clay Nature chemical biology 11 (4), 256-258, 2015 | 119 | 2015 |
Structural and mutational analysis of the nonribosomal peptide synthetase heterocyclization domain provides insight into catalysis K Bloudoff, CD Fage, MA Marahiel, TM Schmeing Proceedings of the National Academy of Sciences 114 (1), 95-100, 2017 | 79 | 2017 |
The B1 protein guides the biosynthesis of a lasso peptide S Zhu, CD Fage, JD Hegemann, A Mielcarek, D Yan, U Linne, ... Scientific reports 6 (1), 1-12, 2016 | 71 | 2016 |
Antimicrobial Peptide Resistance of Vibrio cholerae Results from an LPS Modification Pathway Related to Nonribosomal Peptide Synthetases JC Henderson, CD Fage, JR Cannon, JS Brodbelt, AT Keatinge-Clay, ... ACS chemical biology 9 (10), 2382-2392, 2014 | 66 | 2014 |
The missing linker: a dimerization motif located within polyketide synthase modules J Zheng, CD Fage, B Demeler, DW Hoffman, AT Keatinge-Clay ACS chemical biology 8 (6), 1263-1270, 2013 | 51 | 2013 |
Crystallographic study of the phosphoethanolamine transferase EptC required for polymyxin resistance and motility in Campylobacter jejuni CD Fage, DB Brown, JM Boll, AT Keatinge-Clay, MS Trent Acta Crystallographica Section D: Biological Crystallography 70 (10), 2730-2739, 2014 | 47 | 2014 |
The ring residue proline 8 is crucial for the thermal stability of the lasso peptide caulosegnin II JD Hegemann, CD Fage, S Zhu, K Harms, FS Di Leva, E Novellino, ... Molecular BioSystems 12 (4), 1106-1109, 2016 | 40 | 2016 |
Structure and mechanism of the sphingopyxin I lasso peptide isopeptidase CD Fage, JD Hegemann, AJ Nebel, RM Steinbach, S Zhu, U Linne, ... Angewandte Chemie International Edition 55 (41), 12717-12721, 2016 | 31 | 2016 |
The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl‐Acyl Carrier Protein Binding Site of FabI CD Fage, T Lathouwers, M Vanmeert, LJ Gao, K Vrancken, EM Lammens, ... Angewandte Chemie International Edition 59 (26), 10549-10556, 2020 | 29 | 2020 |
General rules of fragmentation evidencing lasso structures in CID and ETD KJD Fouque, H Lavanant, S Zirah, JD Hegemann, CD Fage, MA Marahiel, ... Analyst 143 (5), 1157-1170, 2018 | 27 | 2018 |
Crystal Structure of Bacillus subtilis Cysteine Desulfurase SufS and Its Dynamic Interaction with Frataxin and Scaffold Protein SufU B Blauenburg, A Mielcarek, F Altegoer, CD Fage, U Linne, G Bange, ... PLoS One 11 (7), e0158749, 2016 | 27 | 2016 |
Dual substrate‐controlled kinase activity leads to polyphosphorylated lasso peptides S Zhu, CD Fage, JD Hegemann, D Yan, MA Marahiel FEBS letters 590 (19), 3323-3334, 2016 | 25 | 2016 |
Communication breakdown: dissecting the COM interfaces between the subunits of nonribosomal peptide synthetases CD Fage, S Kosol, M Jenner, C Oster, A Gallo, M Kaniusaite, R Steinbach, ... ACS Catalysis 11 (17), 10802-10813, 2021 | 17 | 2021 |
Understanding the early stages of peptide formation during the biosynthesis of teicoplanin and related glycopeptide antibiotics M Kaniusaite, J Tailhades, T Kittilä, CD Fage, RJA Goode, ... The FEBS Journal 288 (2), 507-529, 2021 | 17 | 2021 |
Coenzyme A-free activity, crystal structure, and rational engineering of a promiscuous β-ketoacyl thiolase from Ralstonia eutropha CD Fage, JL Meinke, AT Keatinge-Clay Journal of Molecular Catalysis B: Enzymatic 121, 113-121, 2015 | 15 | 2015 |
Simple inhibitors of histone deacetylase activity that combine features of short-chain fatty acid and hydroxamic acid inhibitors JL Tischler, B Abuaita, SC Cuthpert, C Fage, K Murphy, A Saxe, EB Furr, ... Journal of enzyme inhibition and medicinal chemistry 23 (4), 549-555, 2008 | 15 | 2008 |
Recent advances and perspectives on expanding the chemical diversity of lasso peptides M Wang, CD Fage, Y He, J Mi, Y Yang, F Li, X An, H Fan, L Song, S Zhu, ... Frontiers in Bioengineering and Biotechnology 9, 741364, 2021 | 11 | 2021 |
Discovery and characterization of rubrinodin provide clues into the evolution of lasso peptides H Xiu, M Wang, CD Fage, Y He, X Niu, M Han, F Li, X An, H Fan, L Song, ... Biochemistry 61 (7), 595-607, 2022 | 8 | 2022 |