Perturbed length-dependent activation in human hypertrophic cardiomyopathy with missense sarcomeric gene mutations V Sequeira, PJM Wijnker, LLAM Nijenkamp, DWD Kuster, A Najafi, ... Circulation research 112 (11), 1491-1505, 2013 | 216 | 2013 |
Cardiac microvascular endothelial enhancement of cardiomyocyte function is impaired by inflammation and restored by empagliflozin RP Juni, DWD Kuster, M Goebel, M Helmes, RJP Musters, ... JACC: Basic to Translational Science 4 (5), 575-591, 2019 | 170 | 2019 |
Contractile dysfunction irrespective of the mutant protein in human hypertrophic cardiomyopathy with normal systolic function SJ van Dijk, ER Paalberends, A Najafi, M Michels, S Sadayappan, ... Circulation: Heart Failure 5 (1), 36-46, 2012 | 152 | 2012 |
β‐adrenergic receptor signalling and its functional consequences in the diseased heart A Najafi, V Sequeira, DWD Kuster, J van der Velden European journal of clinical investigation 46 (4), 362-374, 2016 | 125 | 2016 |
Towards standardization of echocardiography for the evaluation of left ventricular function in adult rodents: a position paper of the ESC Working Group on Myocardial Function S Zacchigna, A Paldino, I Falcão-Pires, EP Daskalopoulos, M Dal Ferro, ... Cardiovascular research 117 (1), 43-59, 2021 | 112 | 2021 |
Contribution of impaired parasympathetic activity to right ventricular dysfunction and pulmonary vascular remodeling in pulmonary arterial hypertension D da Silva Gonçalves Bós, CEE Van Der Bruggen, K Kurakula, XQ Sun, ... Circulation 137 (9), 910-924, 2018 | 105 | 2018 |
Synergistic role of ADP and Ca2+ in diastolic myocardial stiffness V Sequeira, A Najafi, M McConnell, ED Fowler, IAE Bollen, RCI Wüst, ... The Journal of physiology 593 (17), 3899-3916, 2015 | 77 | 2015 |
Proteomic and functional studies reveal detyrosinated tubulin as treatment target in sarcomere mutation-induced hypertrophic cardiomyopathy M Schuldt, J Pei, M Harakalova, LM Dorsch, S Schlossarek, M Mokry, ... Circulation: Heart Failure 14 (1), e007022, 2021 | 70 | 2021 |
Disturbed cardiac mitochondrial and cytosolic calcium handling in a metabolic risk‐related rat model of heart failure with preserved ejection fraction D Miranda‐Silva, RCI Wüst, G Conceição, P Gonçalves‐Rodrigues, ... Acta Physiologica 228 (3), e13378, 2020 | 69 | 2020 |
GSK3β phosphorylates newly identified site in the proline-alanine–rich region of cardiac myosin–binding protein C and alters cross-bridge cycling kinetics in human DWD Kuster, V Sequeira, A Najafi, NM Boontje, PJM Wijnker, ... Circulation research 112 (4), 633-639, 2013 | 65 | 2013 |
Cardiac myosin binding protein C phosphorylation in cardiac disease DWD Kuster, AC Bawazeer, R Zaremba, M Goebel, NM Boontje, ... Journal of muscle research and cell motility 33, 43-52, 2012 | 65 | 2012 |
Exercise training does not improve cardiac function in compensated or decompensated left ventricular hypertrophy induced by aortic stenosis ED van Deel, M de Boer, DW Kuster, NM Boontje, P Holemans, KR Sipido, ... Journal of molecular and cellular cardiology 50 (6), 1017-1025, 2011 | 65 | 2011 |
Hypertrophic cardiomyopathy: a vicious cycle triggered by sarcomere mutations and secondary disease hits PJM Wijnker, V Sequeira, DWD Kuster, J Velden Antioxidants & redox signaling 31 (4), 318-358, 2019 | 63 | 2019 |
Sex differences at the time of myectomy in hypertrophic cardiomyopathy LLAM Nijenkamp, IAE Bollen, HG van Velzen, JA Regan, ... Circulation: Heart Failure 11 (6), e004133, 2018 | 60 | 2018 |
MicroRNA transcriptome profiling in cardiac tissue of hypertrophic cardiomyopathy patients with MYBPC3 mutations DWD Kuster, J Mulders, FJ Ten Cate, M Michels, CG Dos Remedios, ... Journal of molecular and cellular cardiology 65, 59-66, 2013 | 60 | 2013 |
Myocardial infarction-induced N-terminal fragment of cardiac myosin-binding protein C (cMyBP-C) impairs myofilament function in human myocardium N Witayavanitkul, YA Mou, DWD Kuster, RJ Khairallah, J Sarkey, ... Journal of Biological Chemistry 289 (13), 8818-8827, 2014 | 55 | 2014 |
Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial … J van der Velden, FW Asselbergs, J Bakkers, S Batkai, L Bertrand, ... Cardiovascular research 118 (15), 3016-3051, 2022 | 50 | 2022 |
Detrimental effect of combined exercise training and eNOS overexpression on cardiac function after myocardial infarction MC de Waard, J van der Velden, NM Boontje, DHW Dekkers, ... American Journal of Physiology-Heart and Circulatory Physiology 296 (5 …, 2009 | 49 | 2009 |
Increase in cardiac myosin binding protein-C plasma levels is a sensitive and cardiac-specific biomarker of myocardial infarction S Govindan, DWD Kuster, B Lin, DJ Kahn, WP Jeske, JM Walenga, ... American journal of cardiovascular disease 3 (2), 60, 2013 | 48 | 2013 |
Empagliflozin restores chronic kidney disease–induced impairment of endothelial regulation of cardiomyocyte relaxation and contraction RP Juni, R Al-Shama, DWD Kuster, J van der Velden, HM Hamer, ... Kidney International 99 (5), 1088-1101, 2021 | 47 | 2021 |