The molecular basis for recognition of 5′-NNNCC-3′ PAM and its methylation state by Acidothermus cellulolyticus Cas9 A Das, TH Hand, CL Smith, E Wickline, M Zawrotny, H Li Nature Communications 11 (1), 6346, 2020 | 24 | 2020 |
Structural principles of CRISPR-Cas enzymes used in nucleic acid detection A Das, HN Goswami, CT Whyms, S Sridhara, H Li Journal of structural biology 214 (1), 107838, 2022 | 18 | 2022 |
Molecular mechanism of active Cas7-11 in processing CRISPR RNA and interfering target RNA HN Goswami, J Rai, A Das, H Li Elife 11, e81678, 2022 | 15 | 2022 |
Directed evolution studies of a thermophilic Type II-C Cas9 TH Hand, A Das, H Li Methods in enzymology 616, 265-288, 2019 | 14 | 2019 |
Coupled catalytic states and the role of metal coordination in Cas9 A Das, J Rai, MO Roth, Y Shu, ML Medina, MR Barakat, H Li Nature catalysis 6 (10), 969-977, 2023 | 11 | 2023 |
Phosphate Lock Residues of Acidothermus cellulolyticus Cas9 Are Critical to Its Substrate Specificity TH Hand, A Das, MO Roth, CL Smith, UL Jean-Baptiste, H Li ACS synthetic biology 7 (12), 2908-2917, 2018 | 8 | 2018 |
Structural and Biochemical Analysis of a Methylation Sensitive Cas9 A Das Biophysical Journal 120 (3), 17a, 2021 | | 2021 |
Solvent Accessibility of CRISPR-CAS9 Target DNA is Correlated with Substrate Specificity TH Hand, A Das, E Duboy, M Roth, C Smith, U Baptist, H Li Biophysical Journal 114 (3), 252a, 2018 | | 2018 |