Role of bile acids and bile acid receptors in metabolic regulation P Lefebvre, B Cariou, F Lien, F Kuipers, B Staels Physiological Reviews 89 (1), 147-191, 2009 | 1851 | 2009 |
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease M Pawlak, P Lefebvre, B Staels Journal of Hepatology 62 (3), 720-733, 2015 | 1286 | 2015 |
Sorting out the roles of PPARalpha in energy metabolism and vascular homeostasis P Lefebvre, G Chinetti, J Fruchart, B Staels The Journal of Clinical Investigation 116 (3), 571, 2006 | 1187 | 2006 |
Bile Acid Control of Metabolism and Inflammation in Obesity, Type 2 Diabetes, Dyslipidemia, and Nonalcoholic Fatty Liver Disease O Chávez-Talavera, A Tailleux, P Lefebvre, B Staels Gastroenterology 152 (7), 1679-1694. e3, 2017 | 805 | 2017 |
Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-γ C Rousseaux, B Lefebvre, L Dubuquoy, P Lefebvre, O Romano, J Auwerx, ... The Journal of Experimental Medicine 201 (8), 1205, 2005 | 641 | 2005 |
PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD B Gross,B., Pawlak,M., Lefebvre,P., Staels Nature Rev. Endocrino. 13 (1), 36-49, 2016 | 613* | 2016 |
Transcription factor loading on the MMTV promoter: a bimodal mechanism for promoter activation TK Archer, P Lefebvre, RG Wolford, GL Hager Science 255 (5051), 1573-1576, 1992 | 513 | 1992 |
Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy. E Woldt, Y Sebti, LA Solt, C Duhem, S Lancel, J Eeckhoute, MK Hesselink, ... Nature Medicine 19, 1039–1046, 2013 | 455 | 2013 |
Candida albicans phospholipomannan is sensed through toll-like receptors T Jouault, S Ibata-Ombetta, O Takeuchi, PA Trinel, P Sacchetti, P Lefebvre, ... Journal of Infectious Diseases 188 (1), 165-172, 2003 | 385 | 2003 |
Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells MS Trabelsi, M Daoudi, J Prawitt, S Ducastel, V Touche, SI Sayin, ... Nat. Comm. 6, 7629, 2015 | 365 | 2015 |
PPARα gene expression correlates with severity and histological treatment response in patients with Non-alcoholic Steatohepatitis. SB Francque S, Verrijken A, Caron S, Prawitt J, Paumelle R, Derudas B ... J Hepatol. 63 (1), 164-173, 2015 | 356 | 2015 |
Distinct but complementary contributions of PPAR isotypes to energy homeostasis. V Dubois, J Eeckhoute, P Lefebvre, B Staels J Clin Invest. 127 (4), 1202-1214, 2017 | 330 | 2017 |
Retinoid X receptors: common heterodimerization partners with distinct functions P Lefebvre, Y Benomar, B Staels Trends in Endocrinology & Metabolism 21 (11), 676-683, 2010 | 318 | 2010 |
Daytime variation of perioperative myocardial injury in cardiac surgery and its prevention by Rev-Erbα antagonism: a single-centre propensity-matched cohort study and a … D Montaigne, X Marechal, T Modine, A Coisne, S Mouton, G Fayad, ... The Lancet 391, 59, 2017 | 306 | 2017 |
Myocardial Contractile Dysfunction is Associated with Impaired Mitochondrial Function and Dynamics in Type 2 Diabetic but not in Obese Patients B Montaigne,D, Marechal, X.,.Coisne, A., Debry, N., Modine, T., Fayad, G ... Circulation 130, 554–564, 2014 | 304 | 2014 |
MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids X Fu, B Dong, Y Tian, P Lefebvre, Z Meng, X Wang, F Pattou, W Han, ... The Journal of Clinical Investigation 125 (6), 2497-509, 2015 | 236 | 2015 |
Dynamic hydroxymethylation of deoxyribonucleic acid marks differentiation-associated enhancers AA Sérandour, S Avner, F Oger, M Bizot, F Percevault, ... Nucleic Acids Research 40 (17), 8255-8265, 2012 | 206 | 2012 |
General Molecular Biology and Architecture of Nuclear Receptors M Pawlak, P Lefebvre, B Staels Current Topics in Medicinal Chemistry 12 (6), 486-504, 2012 | 195 | 2012 |
Demonstration of a day-night rhythm in human skeletal muscle oxidative capacity D van Moorsel, J Hansen, B Havekes, FAJL Scheer, JA Jörgensen, ... Mol. Metab. 5 (8), 635-645, 2016 | 193 | 2016 |
Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk F Lien, A Berthier, E Bouchaert, C Gheeraert, J Alexandre, G Porez, ... Journal of Clinical Investigation 124 (3), 1037-1051, 2014 | 180 | 2014 |