Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade A Samson, KJ Scott, D Taggart, EJ West, E Wilson, GJ Nuovo, S Thomson, ... Science translational medicine 10 (422), eaam7577, 2018 | 395 | 2018 |
Neural crest stem cell maintenance by combinatorial Wnt and BMP signaling M Kléber, HY Lee, H Wurdak, J Buchstaller, MM Riccomagno, LM Ittner, ... The Journal of cell biology 169 (2), 309-320, 2005 | 238 | 2005 |
A small molecule primes embryonic stem cells for differentiation S Zhu, H Wurdak, J Wang, CA Lyssiotis, EC Peters, CY Cho, X Wu, ... Cell stem cell 4 (5), 416-426, 2009 | 207 | 2009 |
An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation H Wurdak, S Zhu, A Romero, M Lorger, J Watson, C Chiang, J Zhang, ... Cell stem cell 6 (1), 37-47, 2010 | 186 | 2010 |
Inactivation of TGFβ signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome H Wurdak, LM Ittner, KS Lang, P Leveen, U Suter, JA Fischer, S Karlsson, ... Genes & development 19 (5), 530-535, 2005 | 179 | 2005 |
Compound developmental eye disorders following inactivation of TGFβ signaling in neural-crest stem cells LM Ittner, H Wurdak, K Schwerdtfeger, T Kunz, F Ille, P Leveen, TA Hjalt, ... Journal of biology 4, 1-16, 2005 | 170 | 2005 |
Brain area-specific effect of TGF-β signaling on Wnt-dependent neural stem cell expansion S Falk, H Wurdak, LM Ittner, F Ille, G Sumara, MT Schmid, K Draganova, ... Cell stem cell 2 (5), 472-483, 2008 | 161 | 2008 |
Chemical control of stem cell fate and developmental potential CA Lyssiotis, LL Lairson, AE Boitano, H Wurdak, S Zhu, PG Schultz Angewandte Chemie International Edition 50 (1), 200-242, 2011 | 154 | 2011 |
Wnt/BMP signal integration regulates the balance between proliferation and differentiation of neuroepithelial cells in the dorsal spinal cord F Ille, S Atanasoski, S Falk, LM Ittner, D Märki, S Büchmann-Møller, ... Developmental biology 304 (1), 394-408, 2007 | 148 | 2007 |
RAD51 is a selective DNA repair target to radiosensitize glioma stem cells HO King, T Brend, HL Payne, A Wright, TA Ward, K Patel, T Egnuni, ... Stem cell reports 8 (1), 125-139, 2017 | 141 | 2017 |
Brainstem blood brain barrier disruption using focused ultrasound: A demonstration of feasibility and enhanced doxorubicin delivery S Alli, CA Figueiredo, B Golbourn, N Sabha, MY Wu, A Bondoc, A Luck, ... Journal of controlled release 281, 29-41, 2018 | 133 | 2018 |
A small molecule accelerates neuronal differentiation in the adult rat H Wurdak, S Zhu, KH Min, L Aimone, LL Lairson, J Watson, G Chopiuk, ... Proceedings of the National Academy of Sciences 107 (38), 16542-16547, 2010 | 133 | 2010 |
A genomic screen identifies TYRO3 as a MITF regulator in melanoma S Zhu, H Wurdak, Y Wang, A Galkin, H Tao, J Li, CA Lyssiotis, F Yan, ... Proceedings of the National Academy of Sciences 106 (40), 17025-17030, 2009 | 112 | 2009 |
Spontaneous glioblastoma spheroid infiltration of early-stage cerebral organoids models brain tumor invasion B da Silva, RK Mathew, ES Polson, J Williams, H Wurdak SLAS DISCOVERY: Advancing Life Sciences R&D 23 (8), 862-868, 2018 | 104 | 2018 |
TGF-β promotes microtube formation in glioblastoma through thrombospondin 1 JV Joseph, CR Magaut, S Storevik, LH Geraldo, T Mathivet, MA Latif, ... Neuro-oncology 24 (4), 541-553, 2022 | 70 | 2022 |
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ... Science translational medicine 10 (454), eaar2718, 2018 | 70 | 2018 |
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma HJ Close, LF Stead, J Nsengimana, KA Reilly, A Droop, H Wurdak, ... Clinical & Experimental Immunology 200 (1), 33-44, 2020 | 69 | 2020 |
DiGeorge syndrome and pharyngeal apparatus development H Wurdak, LM Ittner, L Sommer Bioessays 28 (11), 1078-1086, 2006 | 67 | 2006 |
Metastatic site-specific polarization of macrophages in intracranial breast cancer metastases N Rippaus, D Taggart, J Williams, T Andreou, H Wurdak, K Wronski, ... Oncotarget 7 (27), 41473, 2016 | 46 | 2016 |
Regulating the ARNT/TACC3 axis: multiple approaches to manipulating protein/protein interactions with small molecules Y Guo, CL Partch, J Key, PB Card, V Pashkov, A Patel, RK Bruick, ... ACS chemical biology 8 (3), 626-635, 2013 | 41 | 2013 |