Anti-human CD73 monoclonal antibody inhibits metastasis formation in human breast cancer by inducing clustering and internalization of CD73 expressed on the surface of cancer cells MG Terp, KA Olesen, EC Arnspang, RR Lund, BC Lagerholm, HJ Ditzel, ... The Journal of Immunology 191 (8), 4165-4173, 2013 | 157 | 2013 |
Increased cholesterol biosynthesis is a key characteristic of breast cancer stem cells influencing patient outcome S Ehmsen, MH Pedersen, G Wang, MG Terp, A Arslanagic, BL Hood, ... Cell reports 27 (13), 3927-3938. e6, 2019 | 137 | 2019 |
Functional heterogeneity within the CD44 high human breast cancer stem cell-like compartment reveals a gene signature predictive of distant metastasis R Leth-Larsen, MG Terp, AG Christensen, D Elias, T Kühlwein, ... Molecular medicine 18, 1109-1121, 2012 | 93 | 2012 |
Selective elimination of senescent cells by mitochondrial targeting is regulated by ANT2 S Hubackova, E Davidova, K Rohlenova, J Stursa, L Werner, L Andera, ... Cell Death & Differentiation 26 (2), 276-290, 2019 | 92 | 2019 |
Neutrophil extracellular traps formed during chemotherapy confer treatment resistance via TGF-β activation A Mousset, E Lecorgne, I Bourget, P Lopez, K Jenovai, J Cherfils-Vicini, ... Cancer Cell 41 (4), 757-775. e10, 2023 | 54 | 2023 |
Selection of LNA-containing DNA aptamers against recombinant human CD73 IC Elle, KK Karlsen, MG Terp, N Larsen, R Nielsen, N Derbyshire, ... Molecular BioSystems 11 (5), 1260-1270, 2015 | 53 | 2015 |
Co-targeting CDK4/6 and AKT with endocrine therapy prevents progression in CDK4/6 inhibitor and endocrine therapy-resistant breast cancer CL Alves, S Ehmsen, MG Terp, N Portman, M Tuttolomondo, ... Nature Communications 12 (1), 5112, 2021 | 47 | 2021 |
Enapotamab vedotin, an AXL-specific antibody-drug conjugate, shows preclinical antitumor activity in non-small cell lung cancer LA Koopman, MG Terp, GG Zom, ML Janmaat, K Jacobsen, ... JCI insight 4 (21), 2019 | 47 | 2019 |
NADH-cytochrome b5 reductase 3 promotes colonization and metastasis formation and is a prognostic marker of disease-free and overall survival in estrogen receptor-negative … RR Lund, R Leth-Larsen, T Di Caterino, MG Terp, J Nissen, AV Lænkholm, ... Molecular & Cellular Proteomics 14 (11), 2988-2999, 2015 | 44 | 2015 |
Development of a specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo KA Botkjaer, HF Kwok, MG Terp, A Karatt-Vellatt, S Santamaria, ... Oncotarget 7 (13), 16773, 2016 | 42 | 2016 |
Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability KBV Greve, JN Lindgreen, MG Terp, CB Pedersen, S Schmidt, ... Molecular oncology 9 (2), 437-449, 2015 | 41 | 2015 |
Replication and ribosomal stress induced by targeting pyrimidine synthesis and cellular checkpoints suppress p53-deficient tumors S Hubackova, E Davidova, S Boukalova, J Kovarova, M Bajzikova, ... Cell Death & Disease 11 (2), 110, 2020 | 40 | 2020 |
Quantitative proteomics of primary tumors with varying metastatic capabilities using stable isotope‐labeled proteins of multiple histogenic origins RR Lund, MG Terp, AV Lænkholm, ON Jensen, R Leth‐Larsen, HJ Ditzel Proteomics 12 (13), 2139-2148, 2012 | 40 | 2012 |
KDM4B-regulated unfolded protein response as a therapeutic vulnerability in PTEN-deficient breast cancer W Wang, G Oguz, PL Lee, Y Bao, P Wang, MG Terp, HJ Ditzel, Q Yu Journal of Experimental Medicine 215 (11), 2833-2849, 2018 | 37 | 2018 |
Identification of markers associated with highly aggressive metastatic phenotypes using quantitative comparative proteomics MG Terp, RR Lund, ON Jensen, R Leth-Larsen, HJ Ditzel Cancer genomics & proteomics 9 (5), 265-273, 2012 | 34 | 2012 |
Combined FGFR and Akt pathway inhibition abrogates growth of FGFR1 overexpressing EGFR-TKI-resistant NSCLC cells MG Terp, K Jacobsen, MA Molina, N Karachaliou, HC Beck, ... NPJ Precision Oncology 5 (1), 65, 2021 | 25 | 2021 |
miR-155, identified as anti-metastatic by global miRNA profiling of a metastasis model, inhibits cancer cell extravasation and colonization in vivo and causes significant … KG Thomsen, MG Terp, RR Lund, R Søkilde, D Elias, M Bak, T Litman, ... Oncotarget 6 (30), 29224, 2015 | 23 | 2015 |
DDX56 modulates post-transcriptional Wnt signaling through miRNAs and is associated with early recurrence in squamous cell lung carcinoma Q Wu, X Luo, MG Terp, Q Li, Y Li, L Shen, Y Chen, K Jacobsen, ... Molecular cancer 20, 1-17, 2021 | 22 | 2021 |
Remodeling and destabilization of chromosome 1 pericentromeric heterochromatin by SSX proteins S Traynor, NE Møllegaard, MG Jørgensen, NH Brückmann, CB Pedersen, ... Nucleic Acids Research 47 (13), 6668-6684, 2019 | 21 | 2019 |
Co-targeting CDK2 and CDK4/6 overcomes resistance to aromatase and CDK4/6 inhibitors in ER+ breast cancer AJ Al-Qasem, CL Alves, S Ehmsen, M Tuttolomondo, MG Terp, ... NPJ Precision Oncology 6 (1), 68, 2022 | 18 | 2022 |