Mechanical regulation of cardiac fibroblast profibrotic phenotypes KM Herum, J Choppe, A Kumar, AJ Engler, AD McCulloch Molecular biology of the cell 28 (14), 1871-1882, 2017 | 208 | 2017 |
The soft-and hard-heartedness of cardiac fibroblasts: mechanotransduction signaling pathways in fibrosis of the heart KM Herum, IG Lunde, AD McCulloch, G Christensen Journal of clinical medicine 6 (5), 53, 2017 | 178 | 2017 |
Cancer-associated fibroblasts: how do they contribute to metastasis? MQ Kwa, KM Herum, C Brakebusch Clinical & experimental metastasis 36, 71-86, 2019 | 151 | 2019 |
Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress KM Herum, IG Lunde, B Skrbic, G Florholmen, D Behmen, I Sjaastad, ... Journal of molecular and cellular cardiology 54, 73-81, 2013 | 143 | 2013 |
Sweet, yet underappreciated: proteoglycans and extracellular matrix remodeling in heart disease G Christensen, KM Herum, IG Lunde Matrix Biology 75, 286-299, 2019 | 96 | 2019 |
Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan‐4 in cardiac fibroblasts and myocytes, affecting inflammation in the … ME Strand, KM Herum, ZA Rana, B Skrbic, ET Askevold, CP Dahl, ... The FEBS journal 280 (10), 2228-2247, 2013 | 90 | 2013 |
Syndecan-4 is a key determinant of collagen cross-linking and passive myocardial stiffness in the pressure-overloaded heart KM Herum, IG Lunde, B Skrbic, WE Louch, A Hasic, S Boye, A Unger, ... Cardiovascular research 106 (2), 217-226, 2015 | 86 | 2015 |
Syndecans in heart fibrosis IG Lunde, KM Herum, CC Carlson, G Christensen Cell and tissue research 365, 539-552, 2016 | 76 | 2016 |
Lack of collagen VIII reduces fibrosis and promotes early mortality and cardiac dilatation in pressure overload in mice B Skrbic, KVT Engebretsen, ME Strand, IG Lunde, KM Herum, ... Cardiovascular research 106 (1), 32-42, 2015 | 75 | 2015 |
Histamine induces postprandial tachycardia through a direct effect on cardiac H2-receptors in pythons N Skovgaard, K Møller, H Gesser, T Wang American Journal of Physiology-Regulatory, Integrative and Comparative …, 2009 | 65 | 2009 |
Syndecan‐4 protects the heart from the profibrotic effects of thrombin‐cleaved osteopontin KM Herum, A Romaine, A Wang, AO Melleby, ME Strand, J Pacheco, ... Journal of the American Heart Association 9 (3), e013518, 2020 | 42 | 2020 |
Maintaining resting cardiac fibroblasts in vitro by disrupting mechanotransduction G Gilles, AD McCulloch, CH Brakebusch, KM Herum PLoS One 15 (10), e0241390, 2020 | 30 | 2020 |
Overexpression of integrin α11 induces cardiac fibrosis in mice A Romaine, IW Sørensen, C Zeltz, N Lu, PM Erusappan, AO Melleby, ... Acta Physiologica 222 (2), e12932, 2018 | 28 | 2018 |
The heparan sulfate proteoglycan glypican-6 is upregulated in the failing heart, and regulates cardiomyocyte growth through ERK1/2 signaling AO Melleby, ME Strand, A Romaine, KM Herum, B Skrbic, CP Dahl, ... PloS one 11 (10), e0165079, 2016 | 28 | 2016 |
Downregulation of L-type Ca2+ channel in rat mesenteric arteries leads to loss of smooth muscle contractile phenotype and inward hypertrophic remodeling O Kudryavtseva, KM Herum, VS Dam, MS Straarup, D Kamaev, ... American Journal of Physiology-Heart and Circulatory Physiology 306 (9 …, 2014 | 28 | 2014 |
Array atomic force microscopy for real-time multiparametric analysis Q Yang, Q Ma, KM Herum, C Wang, N Patel, J Lee, S Wang, TM Yen, ... Proceedings of the National Academy of Sciences 116 (13), 5872-5877, 2019 | 17 | 2019 |
Fibrotic signaling in cardiac fibroblasts and vascular smooth muscle cells: the dual roles of fibrosis in HFpEF and CAD JC Bachmann, SJ Baumgart, AK Uryga, MH Bosteen, G Borghetti, ... Cells 11 (10), 1657, 2022 | 10 | 2022 |
Cardiac fibroblast sub-types in vitro reflect pathological cardiac remodeling in vivo KM Herum, G Weng, K Kahnert, R Waikel, G Milburn, A Conger, P Anaya, ... Matrix Biology Plus 15, 100113, 2022 | 7 | 2022 |
Histamine induces postprandial tachycardia and mimics the postprandial cardiovascular changes in pythons N Skovgaard, K Møller, H Gesser, T Wang Am J Physiol 296, R774-R785, 2009 | 6 | 2009 |
Integrin α11β1 and syndecan-4 dual receptor ablation attenuate cardiac hypertrophy in the pressure overloaded heart A Romaine, AO Melleby, J Alam, VH Lobert, N Lu, FE Lockwood, A Hasic, ... American Journal of Physiology-Heart and Circulatory Physiology 322 (6 …, 2022 | 5 | 2022 |