The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation L Tornatore, AK Thotakura, J Bennett, M Moretti, G Franzoso Trends in cell biology 22 (11), 557-566, 2012 | 579 | 2012 |
NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration C Mauro, SC Leow, E Anso, S Rocha, AK Thotakura, L Tornatore, ... Nature cell biology 13 (10), 1272-1279, 2011 | 411 | 2011 |
Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal L Di Marcotullio, A Greco, D Mazzà, G Canettieri, L Pietrosanti, P Infante, ... Oncogene 30 (1), 65-76, 2011 | 139 | 2011 |
Identification and characterization of KCASH2 and KCASH3, 2 novel Cullin3 adaptors suppressing histone deacetylase and Hedgehog activity in medulloblastoma E De Smaele, L Di Marcotullio, M Moretti, M Pelloni, MA Occhione, ... Neoplasia 13 (4), 374-IN23, 2011 | 99 | 2011 |
Molecular organization of the cullin E3 ligase adaptor KCTD11 S Correale, L Pirone, L Di Marcotullio, E De Smaele, A Greco, D Mazzà, ... Biochimie 93 (4), 715-724, 2011 | 68 | 2011 |
Cancer: NF-κB regulates energy metabolism M Moretti, J Bennett, L Tornatore, AK Thotakura, G Franzoso The international journal of biochemistry & cell biology 44 (12), 2238-2243, 2012 | 67 | 2012 |
An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastoma E De Smaele, C Fragomeli, E Ferretti, M Pelloni, A Po, G Canettieri, ... Neoplasia 10 (1), 89-IN36, 2008 | 63 | 2008 |
Androgens and hypertension in men and women: a unifying view C Moretti, G Lanzolla, M Moretti, L Gnessi, E Carmina Current hypertension reports 19, 1-8, 2017 | 62 | 2017 |
Blockade of EIF5A hypusination limits colorectal cancer growth by inhibiting MYC elongation S Coni, SM Serrao, ZN Yurtsever, L Di Magno, R Bordone, C Bertani, ... Cell death & disease 11 (12), 1045, 2020 | 59 | 2020 |
Phenformin inhibits hedgehog-dependent tumor growth through a complex I-independent redox/corepressor module L Di Magno, S Manni, F Di Pastena, S Coni, A Macone, S Cairoli, ... Cell reports 30 (6), 1735-1752. e7, 2020 | 56 | 2020 |
The emerging role of the KCTD proteins in cancer A Angrisani, A Di Fiore, E De Smaele, M Moretti Cell Communication and Signaling 19 (1), 56, 2021 | 51 | 2021 |
A smo/gli multitarget hedgehog pathway inhibitor impairs tumor growth L Lospinoso Severini, D Quaglio, I Basili, F Ghirga, F Bufalieri, ... Cancers 11 (10), 1518, 2019 | 46 | 2019 |
ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP F Bufalieri, P Infante, F Bernardi, M Caimano, P Romania, M Moretti, ... Nature communications 10 (1), 3304, 2019 | 42 | 2019 |
Hedgehog-GLI signalling promotes chemoresistance through the regulation of ABC transporters in colorectal cancer cells A Po, A Citarella, G Catanzaro, ZM Besharat, S Trocchianesi, F Gianno, ... Scientific Reports 10 (1), 13988, 2020 | 38 | 2020 |
Foxm1 controls a pro-stemness microRNA network in neural stem cells ZM Besharat, L Abballe, F Cicconardi, A Bhutkar, L Grassi, L Le Pera, ... Scientific reports 8 (1), 3523, 2018 | 37 | 2018 |
Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma P Infante, A Malfanti, D Quaglio, S Balducci, S De Martin, F Bufalieri, ... Cancer letters 499, 220-231, 2021 | 29 | 2021 |
A combination of PARP and CHK1 inhibitors efficiently antagonizes MYCN-driven tumors S Di Giulio, V Colicchia, F Pastorino, F Pedretti, F Fabretti, ... Oncogene 40 (43), 6143-6152, 2021 | 23 | 2021 |
KCTD15 inhibits the Hedgehog pathway in Medulloblastoma cells by increasing protein levels of the oncosuppressor KCASH2 E Spiombi, A Angrisani, S Fonte, G De Feudis, F Fabretti, D Cucchi, ... Oncogenesis 8 (11), 64, 2019 | 23 | 2019 |
Numb isoforms deregulation in medulloblastoma and role of p66 isoform in cancer and neural stem cells L Abballe, A Mastronuzzi, E Miele, A Carai, ZM Besharat, M Moretti, ... Frontiers in Pediatrics 6, 315, 2018 | 12 | 2018 |
Microbiological profiles of dental implants in metabolic syndrome patients: A case-control study B Di Murro, M Moretti, E De Smaele, C Letizia, C Lubrano, PC Passarelli, ... Antibiotics 10 (4), 452, 2021 | 11 | 2021 |