Design, synthesis and evaluation of new quinazolin-4-one derivatives as apoptotic enhancers and autophagy inhibitors with potent antitumor activity HSA ElZahabi, MS Nafie, D Osman, NH Elghazawy, DH Soliman, ... European Journal of Medicinal Chemistry 222, 113609, 2021 | 41 | 2021 |
Discovery of a novel dibromoquinoline compound exhibiting potent antifungal and antivirulence activity that targets metal ion homeostasis H Mohammad, NH Elghazawy, HE Eldesouky, YA Hegazy, W Younis, ... ACS infectious Diseases 4 (3), 403-414, 2018 | 31 | 2018 |
Design and synthesis of novel tamoxifen analogues that avoid CYP2D6 metabolism NS Ahmed, NH Elghazawy, AK ElHady, M Engel, RW Hartmann, ... European Journal of Medicinal Chemistry 112, 171-179, 2016 | 29 | 2016 |
Control of ER-positive breast cancer by ERα expression inhibition, apoptosis induction, cell cycle arrest using semisynthetic isoeugenol derivatives MS Nafie, NH Elghazawy, SM Owf, K Arafa, MA Abdel-Rahman, RK Arafa Chemico-Biological Interactions 351, 109753, 2022 | 22 | 2022 |
Computer-aided design, synthesis and biological characterization of novel inhibitors for PKMYT1 A Najjar, C Platzer, A Luft, CA Aßmann, NH Elghazawy, F Erdmann, ... European Journal of Medicinal Chemistry 161, 479-492, 2019 | 18 | 2019 |
Translational molecular imaging and drug development in Parkinson’s disease A Haider, NH Elghazawy, A Dawoud, C Gebhard, T Wichmann, W Sippl, ... Molecular neurodegeneration 18 (1), 11, 2023 | 17 | 2023 |
Discovery of new 1, 3, 4-oxadiazoles with dual activity targeting the cholinergic pathway as effective anti-Alzheimer agents NH Elghazawy, D Zaafar, RR Hassan, MY Mahmoud, L Bedda, AF Bakr, ... ACS Chemical Neuroscience 13 (8), 1187-1205, 2022 | 13 | 2022 |
Preparation and nanoformulation of new quinolone scaffold-based anticancer agents: Enhancing solubility for better cellular delivery NH Elghazawy, A Hefnawy, NK Sedky, IM El-Sherbiny, RK Arafa European Journal of Pharmaceutical Sciences 105, 203-211, 2017 | 12 | 2017 |
Design and synthesis of novel flexible ester-containing analogs of tamoxifen and their evaluation as anticancer agents NH Elghazawy, M Engel, RW Hartmann, MM Hamed, NS Ahmed, ... Future medicinal chemistry 8 (3), 249-256, 2016 | 11 | 2016 |
Synthesis, molecular modeling and NAD (P) H: quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives MM Ghorab, MS Alsaid, M Higgins, AT Dinkova-Kostova, AA Shahat, ... Journal of Enzyme Inhibition and Medicinal Chemistry 31 (6), 1612-1618, 2016 | 7 | 2016 |
Personalized Medicine and Resurrected Hopes for the Management of Alzheimer’s Disease: A Modular Approach Based on GSK-3β Inhibitors RK Arafa, NH Elghazawy Personalised Medicine: Lessons from Neurodegeneration to Cancer, 199-224, 2017 | 6 | 2017 |
NAD (P) H: quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives MM Ghorab, MS Alsaid, M Higgins, AT Dinkova-Kostova, AA Shahat, ... Drug design, development and therapy, 2515-2524, 2016 | 6 | 2016 |
Imaging Cholinergic Receptors in the Brain by Positron Emission Tomography JJ Zhang, H Fu, R Lin, J Zhou, A Haider, W Fang, NH Elghazawy, J Rong, ... Journal of Medicinal Chemistry 66 (16), 10889-10916, 2023 | 4 | 2023 |
Development and Validation of [3H]OF-NB1 for Preclinical Assessment of GluN1/2B Candidate Drugs H Ahmed, L Gisler, NH Elghazawy, C Keller, W Sippl, SH Liang, A Haider, ... Pharmaceuticals 15 (8), 960, 2022 | 4 | 2022 |
Evaluation of [18F]RoSMA-18-d6 as a CB2 PET Radioligand in Nonhuman Primates A Haider, L Wang, L Gobbi, Y Li, A Chaudhary, X Zhou, J Chen, C Zhao, ... ACS chemical neuroscience 14 (20), 3752-3760, 2023 | 3 | 2023 |
Optical chemosensors for environmental monitoring of toxic metals related to Alzheimer's disease IM El-Sewify, A Radwan, NH Elghazawy, W Fritzsche, HME Azzazy RSC advances 12 (50), 32744-32755, 2022 | 3 | 2022 |
A one-step facile process for extraction of cellulose from rice husk and its use for mechanical reinforcement of dental glass ionomer cement SED Al-Mofty, NH Elghazawy, HME Azzazy RSC Sustainability 1 (7), 1743-1750, 2023 | 2 | 2023 |
Synthesis and Biological Evaluation of Enantiomerically Pure (R)- and (S)-[18F]OF-NB1 for Imaging the GluN2B Subunit-Containing NMDA Receptors M Korff, A Chaudhary, Y Li, X Zhou, C Zhao, J Rong, J Chen, Z Xiao, ... Journal of Medicinal Chemistry 66 (23), 16018-16031, 2023 | 1 | 2023 |
Unleashing new MTDL AChE and BuChE inhibitors as potential anti-AD therapeutic agents: In vitro, in vivo and in silico studies D Zaafar, NH Elghazawy, A Hassan, MY Mahmoud, AF Bakr, RK Arafa International Journal of Biological Macromolecules 268, 131740, 2024 | | 2024 |
Characterization of (R)-and (S)-[18F] OF-NB1 in Rodents as Positron Emission Tomography Probes for Imaging GluN2B Subunit-Containing N-Methyl-d-Aspartate Receptors H Ahmed, R Wallimann, L Gisler, NH Elghazawy, S Gruber, C Keller, ... ACS Chemical Neuroscience 14 (24), 4323-4334, 2023 | | 2023 |