Molecular structure of β-amyloid fibrils in Alzheimer’s disease brain tissue JX Lu, W Qiang, WM Yau, CD Schwieters, SC Meredith, R Tycko Cell 154 (6), 1257-1268, 2013 | 1275 | 2013 |
Structural variation in amyloid-β fibrils from Alzheimer's disease clinical subtypes W Qiang, WM Yau, JX Lu, J Collinge, R Tycko Nature 541 (7636), 217-221, 2017 | 647 | 2017 |
Antiparallel β-sheet architecture in Iowa-mutant β-amyloid fibrils W Qiang, WM Yau, Y Luo, MP Mattson, R Tycko Proceedings of the National Academy of Sciences 109 (12), 4443-4448, 2012 | 396 | 2012 |
Polymorph-specific kinetics and thermodynamics of β-amyloid fibril growth W Qiang, K Kelley, R Tycko Journal of the American Chemical Society 135 (18), 6860-6871, 2013 | 186 | 2013 |
Quaternary structure defines a large class of amyloid-β oligomers neutralized by sequestration P Liu, MN Reed, LA Kotilinek, MKO Grant, CL Forster, W Qiang, ... Cell reports 11 (11), 1760-1771, 2015 | 180 | 2015 |
A strong correlation between fusogenicity and membrane insertion depth of the HIV fusion peptide W Qiang, Y Sun, DP Weliky Proceedings of the National Academy of Sciences 106 (36), 15314-15319, 2009 | 122 | 2009 |
Modeling an in-register, parallel “iowa” aβ fibril structure using solid-state NMR data from labeled samples with rosetta NG Sgourakis, WM Yau, W Qiang Structure 23 (1), 216-227, 2015 | 120 | 2015 |
Structural evolution of Iowa mutant β-amyloid fibrils from polymorphic to homogeneous states under repeated seeded growth W Qiang, WM Yau, R Tycko Journal of the American Chemical Society 133 (11), 4018-4029, 2011 | 116 | 2011 |
HIV fusion peptide penetrates, disorders, and softens T-cell membrane mimics S Tristram-Nagle, R Chan, E Kooijman, P Uppamoochikkal, W Qiang, ... Journal of molecular biology 402 (1), 139-153, 2010 | 91 | 2010 |
Fibrillation of β amyloid peptides in the presence of phospholipid bilayers and the consequent membrane disruption W Qiang, WM Yau, J Schulte Biochimica et Biophysica Acta (BBA)-Biomembranes 1848 (1), 266-276, 2015 | 76 | 2015 |
Distinct membrane disruption pathways are induced by 40-residue β-amyloid peptides DA Delgado, K Doherty, Q Cheng, H Kim, D Xu, H Dong, C Grewer, ... Journal of Biological Chemistry 291 (23), 12233-12244, 2016 | 68 | 2016 |
HIV fusion peptide and its cross-linked oligomers: efficient syntheses, significance of the trimer in fusion activity, correlation of β strand conformation with membrane … W Qiang, DP Weliky Biochemistry 48 (2), 289-301, 2009 | 65 | 2009 |
Solid-state NMR spectroscopy of human immunodeficiency virus fusion peptides associated with host-cell-like membranes: 2D correlation spectra and distance measurements support … W Qiang, ML Bodner, DP Weliky Journal of the American Chemical Society 130 (16), 5459-5471, 2008 | 62 | 2008 |
Flexibility and solvation of amyloid-β hydrophobic core L Vugmeyster, MA Clark, IB Falconer, D Ostrovsky, D Gantz, W Qiang, ... Journal of Biological Chemistry 291 (35), 18484-18495, 2016 | 51 | 2016 |
Molecular structure of an N-terminal phosphorylated β-amyloid fibril ZW Hu, L Vugmeyster, DF Au, D Ostrovsky, Y Sun, W Qiang Proceedings of the National Academy of Sciences 116 (23), 11253-11258, 2019 | 49 | 2019 |
A general Monte Carlo/simulated annealing algorithm for resonance assignment in NMR of uniformly labeled biopolymers KN Hu, W Qiang, R Tycko Journal of biomolecular NMR 50, 267-276, 2011 | 47 | 2011 |
Fabrication and microscopic and spectroscopic characterization of cytocompatible self-assembling antimicrobial nanofibers D Xu, W Chen, YJ Tobin-Miyaji, CR Sturge, S Yang, B Elmore, A Singh, ... ACS infectious diseases 4 (9), 1327-1335, 2018 | 46 | 2018 |
Protonation‐driven membrane insertion of a pH‐low insertion peptide SZ Hanz, NS Shu, J Qian, N Christman, P Kranz, M An, C Grewer, ... Angewandte Chemie 128 (40), 12564-12569, 2016 | 46 | 2016 |
Amyloid-forming segment induces aggregation of FUS-LC domain from phase separation modulated by site-specific phosphorylation X Ding, F Sun, J Chen, L Chen, Y Tobin-Miyaji, S Xue, W Qiang, SZ Luo Journal of molecular biology 432 (2), 467-483, 2020 | 41 | 2020 |
Structural evolution and membrane interaction of the 40-residue β amyloid peptides: differences in the initial proximity between peptides and the membrane bilayer studied by … W Qiang, RD Akinlolu, M Nam, N Shu Biochemistry 53 (48), 7503-7514, 2014 | 40 | 2014 |