X-ray screening identifies active site and allosteric inhibitors of SARS-CoV-2 main protease S Günther, PYA Reinke, Y Fernández-García, J Lieske, TJ Lane, HM Ginn, ... Science 372 (6542), 642-646, 2021 | 284 | 2021 |
Structural basis of IL-1 family cytokine signaling JK Fields, S Günther, EJ Sundberg Frontiers in immunology 10, 1412, 2019 | 256 | 2019 |
A xenon‐129 biosensor for monitoring MHC–peptide interactions A Schlundt, W Kilian, M Beyermann, J Sticht, S Günther, S Höpner, K Falk, ... Angewandte Chemie 121 (23), 4206-4209, 2009 | 109 | 2009 |
Molecular determinants of agonist and antagonist signaling through the IL-36 receptor S Günther, EJ Sundberg The Journal of Immunology 193 (2), 921-930, 2014 | 96 | 2014 |
Bidirectional binding of invariant chain peptides to an MHC class II molecule S Günther, A Schlundt, J Sticht, Y Roske, U Heinemann, KH Wiesmüller, ... Proceedings of the National Academy of Sciences 107 (51), 22219-22224, 2010 | 88 | 2010 |
Crystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodies B Trastoy, JV Lomino, BG Pierce, LG Carter, S Günther, JP Giddens, ... Proceedings of the National Academy of Sciences 111 (18), 6714-6719, 2014 | 71 | 2014 |
IL-1 family cytokines use distinct molecular mechanisms to signal through their shared co-receptor S Günther, D Deredge, AL Bowers, A Luchini, DA Bonsor, R Beadenkopf, ... Immunity 47 (3), 510-523. e4, 2017 | 63 | 2017 |
A novel loop domain in superantigens extends their T cell receptor recognition site S Günther, AK Varma, B Moza, KJ Kasper, AW Wyatt, P Zhu, ... Journal of molecular biology 371 (1), 210-221, 2007 | 63 | 2007 |
On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies J Lieske, M Cerv, S Kreida, D Komadina, J Fischer, M Barthelmess, ... IUCrJ 6 (4), 714-728, 2019 | 55 | 2019 |
Crystal structure of the streptococcal superantigen SpeI and functional role of a novel loop domain in T cell activation by group V superantigens JNP Brouillard, S Günther, AK Varma, I Gryski, CA Herfst, AKMN Rahman, ... Journal of molecular biology 367 (4), 925-934, 2007 | 53 | 2007 |
Structure of Clostridium difficile PilJ exhibits unprecedented divergence from known type IV pilins KH Piepenbrink, GA Maldarelli, CFM De La Peña, GL Mulvey, GA Snyder, ... Journal of Biological Chemistry 289 (7), 4334-4345, 2014 | 48 | 2014 |
MHC class II complexes sample intermediate states along the peptide exchange pathway M Wieczorek, J Sticht, S Stolzenberg, S Günther, C Wehmeyer, Z El Habre, ... Nature Communications 7 (1), 13224, 2016 | 47 | 2016 |
Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules S Gupta, S Höpner, B Rupp, S Günther, K Dickhaut, N Agarwal, ... PloS one 3 (3), e1814, 2008 | 46 | 2008 |
Diverse oligomeric states of CEACAM IgV domains DA Bonsor, S Günther, R Beadenkopf, D Beckett, EJ Sundberg Proceedings of the National Academy of Sciences 112 (44), 13561-13566, 2015 | 43 | 2015 |
Structure and dynamics of FosA-mediated fosfomycin resistance in Klebsiella pneumoniae and Escherichia coli EH Klontz, AD Tomich, S Günther, JA Lemkul, D Deredge, Z Silverstein, ... Antimicrobial agents and chemotherapy 61 (11), 10.1128/aac. 01572-17, 2017 | 41 | 2017 |
Characterization of structural features controlling the receptiveness of empty class II MHC molecules B Rupp, S Günther, T Makhmoor, A Schlundt, K Dickhaut, S Gupta, ... PloS one 6 (4), e18662, 2011 | 35 | 2011 |
Molecular Basis of Broad Spectrum N-Glycan Specificity and Processing of Therapeutic IgG Monoclonal Antibodies by Endoglycosidase S2 EH Klontz, B Trastoy, D Deredge, JK Fields, C Li, J Orwenyo, A Marina, ... ACS Central Science 5 (3), 524-538, 2019 | 33 | 2019 |
Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease V Srinivasan, H Brognaro, PR Prabhu, EE de Souza, S Günther, ... Communications biology 5 (1), 805, 2022 | 21 | 2022 |
Peptide linkage to the α-subunit of MHCII creates a stably inverted antigen presentation complex A Schlundt, S Günther, J Sticht, M Wieczorek, Y Roske, U Heinemann, ... Journal of molecular biology 423 (3), 294-302, 2012 | 21 | 2012 |
Molecular basis of selective cytokine signaling inhibition by antibodies targeting a shared receptor JK Fields, K Kihn, GS Birkedal, EH Klontz, K Sjöström, S Günther, ... Frontiers in Immunology 12, 779100, 2021 | 14 | 2021 |