New Thiazolyl-Pyrazoline derivatives as potential dual EGFR/HER2 inhibitors: design, synthesis, anticancer activity evaluation and in silico study MM Fakhry, AA Mattar, M Alsulaimany, EM Al-Olayan, ST Al-Rashood, ... Molecules 28 (21), 7455, 2023 | 13 | 2023 |
Modulation of NRF2/KEAP1-mediated oxidative stress for cancer treatment by natural products using pharmacophore-based screening, molecular docking, and molecular dynamics studies AA Alzain, RM Mukhtar, N Abdelmoniem, TH Shoaib, W Osman, ... Molecules 28 (16), 6003, 2023 | 10 | 2023 |
Iodoquinazoline-derived VEGFR-2 and EGFRT790M dual inhibitors: Design, synthesis, molecular docking and anticancer evaluations AA Mohamed, SSA El-Hddad, AKB Aljohani, F Khedr, OM Alatawi, ... Bioorganic Chemistry 143, 107062, 2024 | 7 | 2024 |
Introducing of novel class of pyrano[2,3-c]pyrazole-5-carbonitrile analogs with potent antimicrobial activity, DNA gyrase inhibition, and prominent pharmacokinetic … M Almaghrabi, A Musa, AKB Aljohani, HEA Ahmed, M Alsulaimany, ... Journal of Biomolecular Structure and Dynamics 42 (18), 9529-9546, 2024 | 6 | 2024 |
Design, synthesis, docking, ADMET and anticancer evaluations of N-alkyl substituted iodoquinazoline derivatives as dual VEGFR-2 and EGFR inhibitors M Alsulaimany, K El-Adl, AKB Aljohani, HY Alharbi, OM Alatawi, ... RSC advances 13 (51), 36301-36321, 2023 | 5 | 2023 |
Anticancer evaluations of iodoquinazoline substituted with allyl and/or benzyl as dual inhibitors of EGFR WT and EGFR T790M: design, synthesis, ADMET and molecular docking AKB Aljohani, K El-Adl, B Almohaywi, OM Alatawi, M Alsulaimany, ... RSC advances 14 (12), 7964-7980, 2024 | 3 | 2024 |
Development of Novel Class of Phenylpyrazolo[3,4-d]pyrimidine-Based Analogs with Potent Anticancer Activity and Multitarget Enzyme Inhibition Supported by … AKB Aljohani, WAZ El Zaloa, M Alswah, MA Seleem, MM Elsebaei, ... International journal of molecular sciences 24 (19), 15026, 2023 | 2 | 2023 |
Design of new Mcl-1 inhibitors for cancer using fragments hybridization, molecular docking, and molecular dynamics studies AA Alzain, FA Elbadwi, RM Mukhtar, TH Shoaib, N Abdelmoniem, ... Journal of Biomolecular Structure and Dynamics 43 (1), 386-398, 2025 | 1 | 2025 |
Exploration of cytotoxicity of iodoquinazoline derivatives as inhibitors of both VEGFR‐2 and EGFRT790M: Molecular docking, ADMET, design, and syntheses M Alsulaimany, SSA El‐Hddad, ZSM Akrim, AKB Aljohani, B Almohaywi, ... Archiv der Pharmazie 357 (11), e2400389, 2024 | 1 | 2024 |
Dual VEGFR-2 and EGFRT790M inhibitors of phenyldiazenes: anticancer evaluations, ADMET, docking, design and synthesis M Alsulaimany, AKB Aljohani, NEA Abd El-Sattar, SA Almadani, ... Future Medicinal Chemistry, 1-14, 2025 | | 2025 |
Sulfonamide-Pyrazole derivatives as next-generation Cyclooxygenase-2 enzyme inhibitors: From molecular design to in vivo efficacy MK Elgohary, MS Elkotamy, MA Alkabbani, MA El Hassab, ... International Journal of Biological Macromolecules, 139170, 2024 | | 2024 |
Utilization of azamacrocyclic ionophores as recognition elements for the potentiometric determination of gallic acid in various matrices NA Abdallah, RA Al-Haidari, M Alsulaimany, C Simons Microchemical Journal 207, 111804, 2024 | | 2024 |
Rational design and synthesis of novel phenyltriazole derivatives targeting MRSA cell wall biosynthesis MM Elsebaei, HG Ezzat, AM Helal, MH El-Shershaby, MS Abdulrahman, ... RSC advances 14 (54), 39977-39994, 2024 | | 2024 |
Design and synthesis of novel CYP51 inhibitors as therapeutics for candida albicans infections MN Alsulaimany Cardiff University, 2022 | | 2022 |
Study of the Chemo‐sensitizing Effects of Thymoquinone, the Active Constituent of Negilla Sativa (Black Seed), to Nitrogen Mustards, Chlorambucil and … M Alsulaimany, SG Kerr The FASEB Journal 32, 679.2-679.2, 2018 | | 2018 |