关注
Nicolas Wieder
Nicolas Wieder
未知所在单位机构
在 broadinstitute.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models
Y Zhou, P Castonguay, EH Sidhom, AR Clark, M Dvela-Levitt, S Kim, ...
Science 358 (6368), 1332-1336, 2017
1452017
Small molecule targets TMED9 and promotes lysosomal degradation to reverse proteinopathy
M Dvela-Levitt, M Kost-Alimova, M Emani, E Kohnert, R Thompson, ...
Cell 178 (3), 521-535. e23, 2019
1442019
Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies
N Wieder, A Greka
Pediatric Nephrology 31, 1047-1054, 2016
542016
Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease
EH Sidhom, C Kim, M Kost-Alimova, MT Ting, K Keller, J Avila-Pacheco, ...
The Journal of clinical investigation 131 (5), 2021
312021
Exact stochastic simulation of a calcium microdomain reveals the impact of Ca2+ fluctuations on IP3R gating
N Wieder, R Fink, F von Wegner
Biophysical journal 108 (3), 557-567, 2015
252015
GDC-0879, a BRAFV600E inhibitor, protects kidney podocytes from death
J Sieber, N Wieder, A Clark, M Reitberger, S Matan, J Schoenfelder, ...
Cell chemical biology 25 (2), 175-184. e4, 2018
212018
Lysine trimethylation regulates 78-kDa glucose-regulated protein proteostasis during endoplasmic reticulum stress
J Sieber, N Wieder, M Ostrosky-Frid, M Dvela-Levitt, O Aygün, ND Udeshi, ...
Journal of Biological Chemistry 292 (46), 18878-18885, 2017
132017
Microdomain calcium fluctuations as a colored noise process
F von Wegner, N Wieder, RHA Fink
Frontiers in genetics 5, 111517, 2014
112014
Exact and approximate stochastic simulation of intracellular calcium dynamics
N Wieder, RHA Fink, F von Wegner
BioMed Research International 2011, 2011
112011
Simulation strategies for calcium microdomains and calcium-regulated calcium channels
F von Wegner, N Wieder, RHA Fink
Calcium Signaling, 553-567, 2012
62012
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity
N Wieder, JC Fried, C Kim, EH Sidhom, MR Brown, JL Marshall, ...
Cell metabolism 35 (5), 887-905. e11, 2023
52023
Simulation strategies for calcium microdomains and calcium noise
N Wieder, RHA Fink, F von Wegner
Calcium Signaling, 771-797, 2020
42020
Pearls & Oy-sters: A cause of intractable vomiting
LLL Yeo, N Wieder, AS Wang, E Ting, R Rathakrishnan, D Soon
Neurology 83 (15), e141-e144, 2014
12014
Compositions, methods and uses for free fatty acid screening of cells at scale
A Greka, N Wieder, J Coraor
US Patent App. 17/641,683, 2022
2022
Fully Stochastic Simulation of Calcium Microdomains
NW Wieder
2016
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