Inhibiting microcephaly genes as alternative to microtubule targeting agents to treat brain tumors G Iegiani, F Di Cunto, G Pallavicini Cell Death & Disease 12 (11), 1-11, 2021 | 18 | 2021 |
CENPE inhibition leads to mitotic catastrophe and DNA damage in medulloblastoma cells G Iegiani, M Gai, F Di Cunto, G Pallavicini Cancers 13 (5), 1028, 2021 | 18 | 2021 |
CITK loss inhibits growth of group 3 and group 4 medulloblastoma cells and sensitizes them to DNA-damaging agents G Pallavicini, G Iegiani, GE Berto, E Calamia, E Trevisiol, A Veltri, S Allis, ... Cancers 12 (3), 542, 2020 | 16 | 2020 |
The impact of TP53 activation and apoptosis in primary hereditary microcephaly G Iegiani, A Ferraro, G Pallavicini, F Di Cunto Frontiers in Neuroscience 17, 1220010, 2023 | 6 | 2023 |
Potential Therapeutic Effects of the Neural Stem Cell-Targeting Antibody Nilo1 in Patient-Derived Glioblastoma Stem Cells G Rackov, G Iegiani, D Uribe, C Quezada, C Belda-Iniesta, ... Frontiers in oncology 10, 1665, 2020 | 3 | 2020 |
Goldberg–Shprintzen syndrome protein KIF1BP is a CITK interactor implicated in cytokinesis G Pallavicini, M Gai, G Iegiani, GE Berto, A Adrait, Y Couté, F Di Cunto Journal of cell science 134 (11), jcs250902, 2021 | 2 | 2021 |
CITK loss leads to DNA damage accumulation impairing homologous recombination by BRCA1 mislocalization in medulloblastoma G Iegiani, G Pallavicini, M Gai, FD Cunto Brain Tumor Research and Treatment 10 (Suppl), 2022 | 1 | 2022 |
Modeling primary microcephaly with human brain organoids reveals fundamental roles of CIT kinase activity G Pallavicini, A Moccia, G Iegiani, R Parolisi, ER Peirent, GE Berto, ... The Journal of Clinical Investigation, 2024 | | 2024 |
Lestaurtinib inhibits Citron kinase activity and medulloblastoma growth through induction of DNA damage, apoptosis and cytokinesis failure G Pallavicini, G Iegiani, R Parolisi, A Ferraro, F Garello, V Bitonto, ... Frontiers in Oncology 13, 1202585, 2023 | | 2023 |