| The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells WJ Harris, X Huang, JT Lynch, GJ Spencer, JR Hitchin, Y Li, F Ciceri, ... Cancer cell 21 (4), 473-487, 2012 | 643 | 2012 |
| Identification of Protor as a novel Rictor-binding component of mTOR complex-2 LR Pearce, X Huang, J Boudeau, R Pawłowski, S Wullschleger, M Deak, ... Biochemical Journal 405 (3), 513-522, 2007 | 637 | 2007 |
| Important role of the LKB1–AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice X Huang, S Wullschleger, N Shpiro, VA McGuire, K Sakamoto, YL Woods, ... Biochemical Journal 412 (2), 211-221, 2008 | 484 | 2008 |
| HetR homodimer is a DNA-binding protein required for heterocyst differentiation, and the DNA-binding activity is inhibited by PatS X Huang, Y Dong, J Zhao Proceedings of the National Academy of Sciences 101 (14), 4848-4853, 2004 | 212 | 2004 |
| Neuronal polarity is regulated by glycogen synthase kinase-3 (GSK-3β) independently of Akt/PKB serine phosphorylation A Gärtner, X Huang, A Hall Journal of cell science 119 (19), 3927-3934, 2006 | 126 | 2006 |
| CcbP, a calcium-binding protein from Anabaena sp. PCC 7120, provides evidence that calcium ions regulate heterocyst differentiation Y Zhao, Y Shi, W Zhao, X Huang, D Wang, N Brown, J Brand, J Zhao Proceedings of the National Academy of Sciences 102 (16), 5744-5748, 2005 | 95 | 2005 |
| Targeting PI3K/Akt/mTOR in AML: rationale and clinical evidence S Darici, H Alkhaldi, G Horne, HG Jørgensen, S Marmiroli, X Huang Journal of Clinical Medicine 9 (9), 2934, 2020 | 93 | 2020 |
| Loci-specific phase separation of FET fusion oncoproteins promotes gene transcription L Zuo, G Zhang, M Massett, J Cheng, Z Guo, L Wang, Y Gao, R Li, ... Nature communications 12 (1), 1491, 2021 | 83 | 2021 |
| Differential Expression and Localization of Mn and Fe Superoxide Dismutases in the Heterocystous Cyanobacterium Anabaena sp. Strain PCC 7120 T Li, X Huang, R Zhou, Y Liu, B Li, C Nomura, J Zhao Journal of bacteriology 184 (18), 5096-5103, 2002 | 83 | 2002 |
| A targeted knockdown screen of genes coding for phosphoinositide modulators identifies PIP4K2A as required for acute myeloid leukemia cell proliferation and survival JG Jude, GJ Spencer, X Huang, TDD Somerville, DR Jones, N Divecha, ... Oncogene 34 (10), 1253-1262, 2015 | 82 | 2015 |
| Frequent derepression of the mesenchymal transcription factor gene FOXC1 in acute myeloid leukemia TDD Somerville, DH Wiseman, GJ Spencer, X Huang, JT Lynch, ... Cancer cell 28 (3), 329-342, 2015 | 68 | 2015 |
| The emerging role of H3K9me3 as a potential therapeutic target in acute myeloid leukemia L Monaghan, ME Massett, RP Bunschoten, A Hoose, PA Pirvan, ... Frontiers in oncology 9, 705, 2019 | 63 | 2019 |
| Identification of the Active Site of HetR Protease and Its Requirement for Heterocyst Differentiation in the Cyanobacterium Anabaena sp. Strain PCC 7120 Y Dong, X Huang, XY Wu, J Zhao Journal of Bacteriology 182 (6), 1575-1579, 2000 | 45 | 2000 |
| Expression of hetN during heterocyst differentiation and its inhibition of hetR up‐regulation in the cyanobacterium Anabaena sp. PCC 7120 B Li, X Huang, J Zhao FEBS letters 517 (1-3), 87-91, 2002 | 44 | 2002 |
| Enhancers of Polycomb EPC1 and EPC2 sustain the oncogenic potential of MLL leukemia stem cells X Huang, GJ Spencer, JT Lynch, F Ciceri, TDD Somerville, ... Leukemia 28 (5), 1081-1091, 2014 | 41 | 2014 |
| Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3 C Lipina, X Huang, D Finlay, E J McManus, D R. Alessi, C Sutherland Biochemical Journal 392 (3), 633-639, 2005 | 37 | 2005 |
| Abnormal amyloid beta metabolism in systemic abnormalities and Alzheimer’s pathology: Insights and therapeutic approaches from periphery R Ullah, TJ Park, X Huang, MO Kim Ageing Research Reviews 71, 101451, 2021 | 31 | 2021 |
| A KDM4A-PAF1-mediated epigenomic network is essential for acute myeloid leukemia cell self-renewal and survival ME Massett, L Monaghan, S Patterson, N Mannion, RP Bunschoten, ... Cell death & disease 12 (6), 573, 2021 | 26 | 2021 |
| TTC5 is required to prevent apoptosis of acute myeloid leukemia stem cells JT Lynch, TDD Somerville, GJ Spencer, X Huang, TCP Somervaille Cell death & disease 4 (4), e573-e573, 2013 | 14 | 2013 |
| Synergistic cytotoxicity of dual PI3K/mTOR and FLT3 inhibition in FLT3-ITD AML cells S Darici, M Zavatti, L Braglia, B Accordi, V Serafin, GA Horne, L Manzoli, ... Advances in Biological Regulation 82, 100830, 2021 | 11 | 2021 |
Gary SpencerCRUK Manchester Institute在 cruk.manchester.ac.uk 的电子邮件经过验证
