Knockout rats via embryo microinjection of zinc-finger nucleases AM Geurts, GJ Cost, Y Freyvert, B Zeitler, JC Miller, VM Choi, SS Jenkins, ... Science 325 (5939), 433-433, 2009 | 1209 | 2009 |
Gene transfer into genomes of human cells by the sleeping beauty transposon system AM Geurts, Y Yang, KJ Clark, G Liu, Z Cui, AJ Dupuy, JB Bell, ... Molecular Therapy 8 (1), 108-117, 2003 | 442 | 2003 |
Harnessing a high cargo-capacity transposon for genetic applications in vertebrates D Balciunas, KJ Wangensteen, A Wilber, J Bell, A Geurts, S Sivasubbu, ... PLoS genetics 2 (11), e169, 2006 | 361 | 2006 |
Progress and prospects in rat genetics: a community view TJ Aitman, JK Critser, E Cuppen, A Dominiczak, XM Fernandez-Suarez, ... Nature genetics 40 (5), 516-522, 2008 | 353 | 2008 |
Structure–function analysis of the inverted terminal repeats of the Sleeping Beauty transposon Z Cui, AM Geurts, G Liu, CD Kaufman, PB Hackett Journal of molecular biology 318 (5), 1221-1235, 2002 | 290 | 2002 |
Efficient CRISPR/Cas9-mediated genome editing in mice by zygote electroporation of nuclease W Qin, SL Dion, PM Kutny, Y Zhang, AW Cheng, NL Jillette, A Malhotra, ... Genetics 200 (2), 423-430, 2015 | 285 | 2015 |
Genetic mutation of recombination activating gene 1 in Dahl salt-sensitive rats attenuates hypertension and renal damage DL Mattson, H Lund, C Guo, N Rudemiller, AM Geurts, H Jacob American Journal of Physiology-Regulatory, Integrative and Comparative …, 2013 | 201 | 2013 |
Genome editing in rats using zinc-finger nucleases X Cui, AM Geurts, F Urnov US Patent App. 12/592,852, 2010 | 171 | 2010 |
Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling F Moehring, AM Cowie, AD Menzel, AD Weyer, M Grzybowski, T Arzua, ... Elife 7, e31684, 2018 | 165 | 2018 |
Target-site preferences of Sleeping Beauty transposons G Liu, AM Geurts, K Yae, AR Srinivasan, SC Fahrenkrug, ... Journal of molecular biology 346 (1), 161-173, 2005 | 158 | 2005 |
CD247 modulates blood pressure by altering T-lymphocyte infiltration in the kidney N Rudemiller, H Lund, HJ Jacob, AM Geurts, DL Mattson Hypertension 63 (3), 559-564, 2014 | 156 | 2014 |
Gene targeting in the rat: advances and opportunities HJ Jacob, J Lazar, MR Dwinell, C Moreno, AM Geurts Trends in Genetics 26 (12), 510-518, 2010 | 156 | 2010 |
Increased expression of NAD (P) H oxidase subunit p67phox in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension D Feng, C Yang, AM Geurts, T Kurth, M Liang, J Lazar, DL Mattson, ... Cell metabolism 15 (2), 201-208, 2012 | 149 | 2012 |
Generation of gene-specific mutated rats using zinc-finger nucleases AM Geurts, GJ Cost, S Rémy, X Cui, L Tesson, C Usal, S Ménoret, ... Rat Genomics: Methods and Protocols, 211-225, 2010 | 131 | 2010 |
Identifying multiple causative genes at a single GWAS locus MJ Flister, SW Tsaih, CC O'Meara, B Endres, MJ Hoffman, AM Geurts, ... Genome research 23 (12), 1996-2002, 2013 | 126 | 2013 |
A NOX4/TRPC6 pathway in podocyte calcium regulation and renal damage in diabetic kidney disease DV Ilatovskaya, G Blass, O Palygin, V Levchenko, TS Pavlov, ... Journal of the American Society of Nephrology 29 (7), 1917-1927, 2018 | 121 | 2018 |
Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers AM Geurts, LS Collier, JL Geurts, LL Oseth, ML Bell, D Mu, R Lucito, ... PLoS genetics 2 (9), e156, 2006 | 111 | 2006 |
Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits K Katter, AM Geurts, O Hoffmann, L Mátés, V Landa, L Hiripi, C Moreno, ... The FASEB Journal 27 (3), 930, 2013 | 108 | 2013 |
Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons Z Ivics, W Garrels, L Mátés, TY Yau, S Bashir, V Zidek, V Landa, A Geurts, ... Nature protocols 9 (4), 810-827, 2014 | 107 | 2014 |
Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system B Lu, AM Geurts, C Poirier, DC Petit, W Harrison, PA Overbeek, ... Mammalian Genome 18, 338-346, 2007 | 99 | 2007 |