Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites PN Cockerill, WT Garrard Cell 44 (2), 273-282, 1986 | 1136 | 1986 |
Tumor necrosis factor-α induces adhesion molecule expression through the sphingosine kinase pathway P Xia, JR Gamble, KA Rye, L Wang, CST Hii, P Cockerill, Y Khew-Goodall, ... Proceedings of the National Academy of Sciences 95 (24), 14196-14201, 1998 | 530 | 1998 |
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma B Lamprecht, K Walter, S Kreher, R Kumar, M Hummel, D Lenze, ... Nature medicine 16 (5), 571-579, 2010 | 399 | 2010 |
The enhancer of the immunoglobulin heavy chain locus is flanked by presumptive chromosomal loop anchorage elements. PN Cockerill, MH Yuen, WT Garrard Journal of Biological Chemistry 262 (11), 5394-5397, 1987 | 308 | 1987 |
Wellington: a novel method for the accurate identification of digital genomic footprints from DNase-seq data J Piper, MC Elze, P Cauchy, PN Cockerill, C Bonifer, S Ott Nucleic acids research 41 (21), e201-e201, 2013 | 245 | 2013 |
The granulocyte-macrophage colony-stimulating factor/interleukin 3 locus is regulated by an inducible cyclosporin A-sensitive enhancer. PN Cockerill, MF Shannon, AG Bert, GR Ryan, MA Vadas Proceedings of the National Academy of Sciences 90 (6), 2466-2470, 1993 | 228 | 1993 |
Depletion of RUNX1/ETO in t (8; 21) AML cells leads to genome-wide changes in chromatin structure and transcription factor binding A Ptasinska, SA Assi, D Mannari, SR James, D Williamson, J Dunne, ... Leukemia 26 (8), 1829-1841, 2012 | 206 | 2012 |
A simplified method for quantitation of the relative amounts of type I and type III collagen in small tissue samples GJ Laurent, P Cockerill, RJ McAnulty, JRB Hastings Analytical biochemistry 113 (2), 301-312, 1981 | 188 | 1981 |
The LPS-induced transcriptional upregulation of the chicken lysozyme locus involves CTCF eviction and noncoding RNA transcription P Lefevre, J Witham, CE Lacroix, PN Cockerill, C Bonifer Molecular cell 32 (1), 129-139, 2008 | 179 | 2008 |
Subtype-specific regulatory network rewiring in acute myeloid leukemia SA Assi, MR Imperato, DJL Coleman, A Pickin, S Potluri, A Ptasinska, ... Nature genetics 51 (1), 151-162, 2019 | 175 | 2019 |
Structure and function of active chromatin and DNase I hypersensitive sites PN Cockerill The FEBS journal 278 (13), 2182-2210, 2011 | 153 | 2011 |
Chromosomal loop anchorage sites appear to be evolutionarily conserved PN Cockerill, WT Garrard FEBS letters 204 (1), 5-7, 1986 | 150 | 1986 |
Identification of a dynamic core transcriptional network in t (8; 21) AML that regulates differentiation block and self-renewal A Ptasinska, SA Assi, N Martinez-Soria, MR Imperato, J Piper, P Cauchy, ... Cell reports 8 (6), 1974-1988, 2014 | 145 | 2014 |
Human granulocyte-macrophage colony-stimulating factor enhancer function is associated with cooperative interactions between AP-1 and NFATp/c PN Cockerill, AG Bert, F Jenkins, GR Ryan, MF Shannon, MA Vadas Molecular and cellular biology, 1995 | 143 | 1995 |
Regulation of granulocyte-macrophage colony-stimulating factor and E-selectin expression in endothelial cells by cyclosporin A and the T-cell transcription factor NFAT GW Cockerill, AG Bert, GR Ryan, JR Gamble, MA Vadas, PN Cockerill | 127 | 1995 |
Inducible chromatin priming is associated with the establishment of immunological memory in T cells SL Bevington, P Cauchy, J Piper, E Bertrand, N Lalli, RC Jarvis, ... The EMBO journal 35 (5), 515-535, 2016 | 108 | 2016 |
AT cell–specific enhancer in the interleukin-3 locus is activated cooperatively by Oct and NFAT elements within a DNase I–hypersensitive site KN Duncliffe, AG Bert, MA Vadas, PN Cockerill Immunity 6 (2), 175-185, 1997 | 103 | 1997 |
The oncogenic transcription factor RUNX1/ETO corrupts cell cycle regulation to drive leukemic transformation N Martinez-Soria, L McKenzie, J Draper, A Ptasinska, H Issa, S Potluri, ... Cancer Cell 34 (4), 626-642. e8, 2018 | 100 | 2018 |
Prospective isolation and characterization of genetically and functionally distinct AML subclones B de Boer, J Prick, MG Pruis, P Keane, MR Imperato, J Jaques, ... Cancer cell 34 (4), 674-689. e8, 2018 | 100 | 2018 |
Signals for activation of the GM-CSF promoter and enhancer in T cells MF Shannon, LS Coles, MA Vadas, PN Cockerill Critical Reviews™ in Immunology 17 (3-4), 1997 | 99 | 1997 |